elderly – Medxy AI

Bivalent RSV Prefusion F Protein Vaccine: A Potential Strategy to Reduce Cardiovascular Hospitalizations in Older Adults

By MedXY 09/01/2025

The DAN-RSV trial demonstrates that RSV vaccination significantly lowers all-cause cardiorespiratory hospitalizations among older adults, suggesting vaccines may reduce infection-triggered cardiovascular complications and benefit chronic disease management.

Clinical Updates Wellness & Lifestyle

Reevaluating Antihypertensive Therapy in Frail Elderly Nursing Home Residents: Insights from the RETREAT-FRAIL Trial

By MedXY 08/30/2025

The RETREAT-FRAIL trial found no survival benefit from progressively reducing antihypertensive medications in frail nursing home residents aged ≥80 with controlled blood pressure, supporting individualized treatment strategies.

Clinical Updates Wellness & Lifestyle

No Added Survival Benefit from Adjuvant Chemotherapy in Older Women with Genomically High-Risk Hormone Receptor-Positive Breast Cancer: Results from the ASTER 70s Trial

By MedXY 08/07/2025

The ASTER 70s trial found that adding chemotherapy to hormonotherapy did not improve survival but increased toxicity in women aged 70+ with high-risk ER+/HER2- breast cancer.

Clinical Updates Wellness & Lifestyle

High-Dose and Adjuvanted Flu Vaccines Offer Equivalent Protection for Older US Adults

By MedXY 07/31/2025

A large US study finds adjuvanted and high-dose quadrivalent influenza vaccines provide comparable protection against lab-confirmed flu in seniors, supporting current immunization guidelines.

Clinical Updates Wellness & Lifestyle

Inconsistent Bone Health Management in Older Women With Breast Cancer: Insights From the Age Gap Study

By MedXY 07/31/2025

Significant variation exists in bone health management for older women receiving endocrine therapy for breast cancer, highlighting the need for standardized care.

Clinical Updates Wellness & Lifestyle

GLP-1 Receptor Agonists and Dementia Risk in Older Adults With Type 2 Diabetes: Insights From a Target Trial Emulation

By MedXY 07/31/2025

A large-scale emulated trial found no clear overall reduction in dementia risk with GLP-1 receptor agonists versus DPP-4 inhibitors in older adults with type 2 diabetes, though age-specific effects warrant further investigation.