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Diacerein

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Diacerein Fails to Outperform Placebo in Patients with Inflammatory Phenotype Knee Osteoarthritis
Posted innews Orthopedics Rheumatology

Diacerein Fails to Outperform Placebo in Patients with Inflammatory Phenotype Knee Osteoarthritis

Posted by MedXY By MedXY 03/02/2026
A multicenter randomized trial shows diacerein provides no clinical benefit over placebo for knee pain in patients with MRI-confirmed inflammation, despite its theoretical role as an IL-1β blocker.
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