Dementia – Medxy AI

Elevated Risk of Alzheimer’s Disease and Related Dementias in Transfeminine Adults: Insights from a Large Cohort Study

By MedXY 08/02/2025

Recent data reveal that transfeminine adults experience significantly higher prevalence of Alzheimer's disease and related dementias compared to matched cisgender peers, independent of gender-affirming hormone therapy, highlighting urgent needs for targeted research and care strategies.

Clinical Updates Wellness & Lifestyle

GLP-1 Receptor Agonists and Dementia Risk in Older Adults With Type 2 Diabetes: Insights From a Target Trial Emulation

By MedXY 07/31/2025

A large-scale emulated trial found no clear overall reduction in dementia risk with GLP-1 receptor agonists versus DPP-4 inhibitors in older adults with type 2 diabetes, though age-specific effects warrant further investigation.

Clinical Updates Medical News

Structured Lifestyle Interventions Deliver Superior Cognitive Benefits over Self-Guided Approaches in At-Risk Older Adults

By MedXY 07/29/2025

A large phase 3 trial reveals that structured, multidomain lifestyle interventions significantly improve cognition in older adults at risk for cognitive decline, outperforming self-guided strategies.