Dementia – Medxy AI

Women Face Higher Dementia Risk from Combined Vascular and Genetic Factors: Insights from the ARIC Study

By MedXY 01/29/2026

A longitudinal study of 12,268 participants reveals that women are more susceptible to cognitive decline and dementia when burdened by high blood pressure and the APOE ε4 allele compared to men.

Neurology news Psychiatry

Reevaluating the Efficacy of Music Interventions in Dementia-Related Depression: Critical Insights from the MIDDEL Multinational Trial

By Zhang Paul 01/13/2026

Highlights The MIDDEL trial found that neither group music therapy nor recreational choir singing significantly…

Emergency Medicine Internal Medicine Neurology news

One in Three Older Emergency Admissions Face Cognitive Morbidity: Insights from the ORCHARD-EPR Study

By MedXY 12/29/2025

A large-scale cross-sectional study of 51,202 admissions reveals that 35.6% of patients aged 70 and older experience cognitive morbidity, predominantly delirium. The findings underscore the urgent necessity for hospital-wide screening and multidisciplinary geriatric support across nearly all medical and surgical specialties.

Cardiology Neurology news

Lipoprotein(a) and Dementia: Large Cohorts Show No Clear Link — But Small Apo(a) Isoforms May Raise Alzheimer’s Risk

By MedXY 11/28/2025

A pooled analysis of three large cohorts found no consistent association between circulating lipoprotein(a) and Alzheimer’s disease or vascular dementia, but genetic evidence for very small apo(a) isoforms suggests a modest increase in Alzheimer’s risk.

Neurology news Specialties

APOE ε4 Allele as an Independent Predictor of Survival in Parkinson’s Disease Patients

By MedXY 10/21/2025

The APOE ε4 allele significantly reduces survival in Parkinson's disease patients independently of dementia, linked to mitochondrial dysfunction and ER stress in PD models.

Family Medicine & Nutrition Neurology news Specialties

APOE ε4 Allele: A Key Driver of Cognitive Decline and Neurodegeneration in Older Adults from the Democratic Republic of the Congo

By MedXY 10/21/2025

This study reveals that the APOE ε4 allele is linked to increased dementia prevalence, cognitive deficits, brain atrophy, and plasma biomarkers of neurodegeneration in older adults in the DRC, emphasizing its critical role in African populations.

Neurology news Public Health

Evolving Landscape of Modifiable Dementia Risk Factors in Australia: Socioeconomic and Sex Disparities Over 15 Years

By MedXY 10/20/2025

This analysis reveals stable dementia risk fractions despite changing risk profiles over 15 years in Australia, highlighting greater modifiable risk among low-income groups and males, with depression emerging as a leading factor in mid-life, especially in women and disadvantaged populations.

Family Medicine & Nutrition Neurology Specialties

Dietary Patterns and Dementia Risk: Insights from a Large UK Biobank Cohort Study

By MedXY 10/20/2025

Higher adherence to Mediterranean, MIND, and Recommended Food Score diets is linked to reduced risk of all-cause dementia and Alzheimer disease, highlighting diet as a modifiable factor in dementia prevention.

Internal Medicine Neurology news

Aspirin Use in Older Adults: Insights from the ASPREE-XT Study on Healthy Lifespan

By MedXY 10/07/2025

Extended follow-up from the ASPREE-XT study shows low-dose aspirin does not improve healthy lifespan—defined as survival free of dementia, persistent disability, or death—in healthy older adults, and its risks include increased major hemorrhagic events.

Diabetes & Endocrinology Neurology news Specialties

Metabolic Syndrome: The Hidden Highway to Dementia in Older Adults

By MedXY 08/26/2025

Metabolic syndrome—characterized by five key metabolic risk factors—significantly increases the risk of dementia, especially vascular dementia, among older adults. Early detection and lifestyle interventions are crucial to protect brain health.

Family Medicine & Nutrition Neurology news Specialties

13 Brain-Boosting Foods to Help Fight Dementia: Are You Eating These?

By MedXY 08/26/2025

Discover 13 scientifically-supported foods that can help protect and enhance cognitive function, potentially reducing dementia risk as you age.

Clinical Updates Emergency Medicine Internal Medicine news Specialties

Delirium in Acute General Medicine: A Decade-Long Study on Occurrence, Risk Factors, and Long-Term Outcomes

By MedXY 08/16/2025

This 10-year study from England details delirium's prevalence, associated factors like dementia and frailty, and its lasting impact on mortality and care needs in acute general medicine patients, supporting targeted screening and intervention.

Clinical Updates Neurology news Specialties

Culturally Adapted Dementia Caregiver Support in Vietnam: New Evidence from the REACH VN Clinical Trial

By MedXY 08/08/2025

A culturally adapted, multicomponent caregiver intervention (REACH VN) reduced psychological distress and stress among Vietnamese dementia caregivers at 3 months, though most benefits were not sustained at 6 months, highlighting both promise and challenges for scalable dementia care support in low-resource settings.

Neurology news Specialties

Subtle Signs of Dementia: Understanding Early Symptoms and Prevention

By MedXY 08/06/2025

Explore ten often-overlooked early signs of dementia, their implications, and evidence-based prevention strategies.

Medical News Neurology news Specialties

Why Does Dementia Diagnosis Take So Long? Insights from a Major Meta-Analysis

By MedXY 08/05/2025

A new meta-analysis finds that the average time from dementia symptom onset to diagnosis is 3.5 years, with even longer delays in younger patients and those with frontotemporal dementia.

Family Medicine & Nutrition Medical News Neurology news Specialties

Can Preventing Herpes Reduce Dementia Risk? New Science Links Cold Sores, Shingles, and Alzheimer’s Disease

By MedXY 08/04/2025

Emerging research reveals a compelling connection between common herpes viruses and dementia risk, with vaccination and antiviral treatments showing promise for prevention.

Medical News Neurology news Specialties

Can Preventing Herpes Reduce Dementia Risk? New Science Links Cold Sores, Shingles, and Alzheimer’s Disease

By MedXY 08/04/2025

Emerging research reveals a compelling connection between common herpes viruses and dementia risk, with vaccination and antiviral treatments showing promise for prevention.

Neurology news Specialties

Understanding and Managing Alzheimer’s Disease: A Comprehensive Guide

By MedXY 08/03/2025

An in-depth overview of Alzheimer's disease, covering its causes, symptoms, diagnosis, treatment options, and caregiving strategies.

Clinical Updates Neurology news Specialties

Elevated Risk of Alzheimer’s Disease and Related Dementias in Transfeminine Adults: Insights from a Large Cohort Study

By MedXY 08/02/2025

Recent data reveal that transfeminine adults experience significantly higher prevalence of Alzheimer's disease and related dementias compared to matched cisgender peers, independent of gender-affirming hormone therapy, highlighting urgent needs for targeted research and care strategies.

Clinical Updates Diabetes & Endocrinology news Specialties

GLP-1 Receptor Agonists and Dementia Risk in Older Adults With Type 2 Diabetes: Insights From a Target Trial Emulation

By MedXY 07/31/2025

A large-scale emulated trial found no clear overall reduction in dementia risk with GLP-1 receptor agonists versus DPP-4 inhibitors in older adults with type 2 diabetes, though age-specific effects warrant further investigation.