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TP53-Mutated Clonal Hematopoiesis Drives Pro-Inflammatory Phenotype and Predicts Poor Outcomes After CAR T-Cell Therapy
Posted inHematology-Oncology news

TP53-Mutated Clonal Hematopoiesis Drives Pro-Inflammatory Phenotype and Predicts Poor Outcomes After CAR T-Cell Therapy

Posted by By MedXY 08/26/2026
TP53-mutant clonal hematopoiesis in CAR T-cell recipients is linked to a pro-inflammatory state, cytopenias, and worse survival, highlighting the importance of tailored monitoring strategies in this high-risk group.
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Pre-diagnostic Clonal Hematopoiesis Raises Risk of Second Cancers in Patients With Primary Cancer
Posted inHematology-Oncology news Oncology

Pre-diagnostic Clonal Hematopoiesis Raises Risk of Second Cancers in Patients With Primary Cancer

Posted by By MedXY 06/08/2026
Patients with primary cancer who had pre-diagnostic CHIP faced a higher risk of second cancers, especially blood cancers. The findings suggest CHIP may help identify survivors who need closer long-term monitoring.
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Navigating Childhood Insurance in the US: Insights into Medicaid, CHIP, and Uninsurance Dynamics
Posted innews Pediatrics Public Health Specialties

Navigating Childhood Insurance in the US: Insights into Medicaid, CHIP, and Uninsurance Dynamics

Posted by By MedXY 09/28/2025
A simulation study reveals that 75% of US children experience publicly subsidized insurance or uninsurance periods by age 18, highlighting the impact of state Medicaid policies on pediatric coverage gaps.
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  • Clinical Utility of a 30% Reduction in VCTE-Derived Liver Stiffness Measurement for Identifying Histologic Improvement in Metabolic Dysfunction-Associated Steatohepatitis
  • Reevaluating Colorectal Cancer Surveillance in Inflammatory Bowel Disease: The Role of Family History Beyond Early-Onset Cases
  • Ticagrelor-Aspirin Dual Therapy After Thrombolysis in Moderate Ischemic Stroke: Insights from Infarct Patterns in the TAPIS Trial
  • Cilostazol Therapy in Intracerebral Hemorrhage: Enhancing Dural Lymphatic Function for Neuroprotection
  • CSF Biomarkers as Indicators of Disease Severity in Probable Cerebral Amyloid Angiopathy: Insights Beyond MRI
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