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Revisiting Pharmacotherapy in Nonobstructive Hypertrophic Cardiomyopathy: Insights from a Randomized Triple-Crossover Trial of Bisoprolol vs. Verapamil
A pivotal triple-crossover RCT reveals that while bisoprolol reduces exercise capacity and worsens diastolic markers in nonobstructive HCM, verapamil maintains exercise performance and improves myocardial strain.