Posted inCardiology news Oncology
The BMPR2 Nexus: How Breast Cancer Acts as a Second Hit for Pulmonary Hypertension
Emerging evidence identifies a bidirectional link between breast cancer and pulmonary arterial hypertension (PAH) driven by BMPR2 signaling and IL-1β-mediated inflammation. This study suggests breast cancer may serve as a critical second hit, unmasking latent vascular susceptibility in at-risk populations.