Distinct Neuroimaging Signatures: Atrial Fibrillation and Atherosclerosis Drive Divergent Vascular Brain Lesion Patterns

Distinct Neuroimaging Signatures: Atrial Fibrillation and Atherosclerosis Drive Divergent Vascular Brain Lesion Patterns

A large-scale comparative study of 3,508 patients reveals that atrial fibrillation and atherosclerosis produce significantly different vascular brain lesions on MRI, with AF favoring non-lacunar infarcts and periventricular white matter changes, while atherosclerosis is linked to lacunar infarcts and micro-bleeds.
Elevated Blood Pressure in Adolescence Predicts Dose‑Dependent Coronary Atherosclerosis in Middle Age: Implications for Early Detection and Prevention

Elevated Blood Pressure in Adolescence Predicts Dose‑Dependent Coronary Atherosclerosis in Middle Age: Implications for Early Detection and Prevention

A Swedish cohort study of 10,222 men linked adolescent blood pressure to coronary atherosclerosis by CCTA ~40 years later; higher systolic BP in adolescence, even in the ‘elevated’ range, was associated with greater odds of severe (>50%) coronary stenosis in middle age.