Amyloid PET Centiloid Predicts Lifetime and 10‑Year Risk of MCI and Dementia in Cognitively Unimpaired Adults
A large Mayo Clinic Study of Aging analysis shows lifetime and 10‑year absolute risk of MCI and dementia rise monotonically with amyloid PET centiloid values, modified by age, sex, and APOE ε4 status; out‑of‑study ascertainment substantially affects estimates.