Music Therapy Proves Noninferior to Cognitive Behavioral Therapy for Managing Anxiety in Cancer Survivors: Results from a Randomized Trial
Posted inHematology-Oncology news Oncology Psychiatry

Music Therapy Proves Noninferior to Cognitive Behavioral Therapy for Managing Anxiety in Cancer Survivors: Results from a Randomized Trial

A randomized clinical trial demonstrates that telehealth-delivered music therapy is noninferior to cognitive behavioral therapy for reducing anxiety in cancer survivors, providing durable, clinically meaningful improvements and a viable alternative to traditional psychological interventions.
The Hidden Burden of Heart and Brain Health: ASCVD Linked to Significantly Elevated Suicide Risk
Posted inCardiology news Psychiatry

The Hidden Burden of Heart and Brain Health: ASCVD Linked to Significantly Elevated Suicide Risk

A large-scale nationwide study reveals that individuals with atherosclerotic cardiovascular disease (ASCVD), including myocardial infarction and stroke, face a 43% higher risk of suicide. The risk nearly doubles for those suffering from both conditions, highlighting an urgent need for mental health integration in cardiovascular care.
Beyond Picky Eating: Large-Scale Study Reveals the Genetic Architecture and Developmental Impact of ARFI Phenotypes
Posted innews Pediatrics Psychiatry

Beyond Picky Eating: Large-Scale Study Reveals the Genetic Architecture and Developmental Impact of ARFI Phenotypes

This large-scale study of 35,751 children characterizes ARFI phenotypes, revealing a 6.3% clinical prevalence and significant genetic heritability. Findings link ARFI to the ADCY3 locus and long-term neurodevelopmental difficulties, emphasizing the need for early identification and broad support interventions.
Neuropsychiatric Interaction with Vascular Health: Deciphering the Moderating Role of PTSD in Hormonal Contraceptive-Associated Cardiovascular Risk
Posted inClinical Updates Neurology news Psychiatry

Neuropsychiatric Interaction with Vascular Health: Deciphering the Moderating Role of PTSD in Hormonal Contraceptive-Associated Cardiovascular Risk

A large-scale cohort study demonstrates that while hormonal contraceptives are generally associated with lower cardiovascular risk in women, this protective effect is lost in those with PTSD, highlighting a critical intersection between psychiatric health and reproductive medicine.
Digital Phenotyping in Insomnia: Real-Time Smartphone Assessment Detects Daytime Benefits of Suvorexant Missed by Traditional Scales
Posted inNeurology news Psychiatry

Digital Phenotyping in Insomnia: Real-Time Smartphone Assessment Detects Daytime Benefits of Suvorexant Missed by Traditional Scales

A randomized clinical trial demonstrates that smartphone-based ecological momentary assessment (EMA) is significantly more sensitive than retrospective questionnaires in detecting the daytime clinical benefits of suvorexant, particularly regarding fatigue and subjective cognition in older adults with chronic insomnia.
The Limits of Collaborative Care: Why the CLARO Trial Found No Added Benefit for OUD and Comorbid Mental Illness
Posted inInternal Medicine news Psychiatry

The Limits of Collaborative Care: Why the CLARO Trial Found No Added Benefit for OUD and Comorbid Mental Illness

The CLARO randomized clinical trial investigated whether a collaborative care model could improve outcomes for patients with opioid use disorder and co-occurring depression or PTSD. The study found no statistically significant advantages over enhanced usual care, suggesting challenges in implementing these models for complex, low-resource populations.
Lifespan Management of ADHD: Landmark Umbrella Review Identifies Optimal Interventions and Critical Evidence Gaps
Posted innews Pediatrics Psychiatry

Lifespan Management of ADHD: Landmark Umbrella Review Identifies Optimal Interventions and Critical Evidence Gaps

A comprehensive BMJ umbrella review synthesizes evidence for ADHD interventions across the lifespan, confirming the efficacy of stimulants and non-stimulants in the short term while revealing a critical lack of high-certainty long-term data and introducing a new digital platform for shared clinical decision-making.
Unlocking the Sleeper Effect: Can Mechanism-Based Psychological Interventions Transform IBS and UC Outcomes?
Posted inGastroenterology news Psychiatry

Unlocking the Sleeper Effect: Can Mechanism-Based Psychological Interventions Transform IBS and UC Outcomes?

The SOMA.GUT-RCT investigated a targeted psychological intervention for IBS and UC. While the primary 3-month endpoint showed no significant symptom reduction compared to standard care, exploratory data revealed significant psychological improvements and a delayed clinical benefit at 12 months, highlighting the potential for integrated care.
Antiviral Therapy Fails to Slow Alzheimer’s: The VALAD Trial Reveals Unexpected Cognitive Worsening with Valacyclovir
Posted inNeurology news Psychiatry

Antiviral Therapy Fails to Slow Alzheimer’s: The VALAD Trial Reveals Unexpected Cognitive Worsening with Valacyclovir

The VALAD randomized clinical trial found that valacyclovir did not improve outcomes in patients with early symptomatic Alzheimer’s and HSV seropositivity. Instead, patients receiving the antiviral showed significantly greater cognitive decline compared to placebo over 78 weeks, cautioning against off-label use.