Deciphering Prenatal Risks: Why Maternal Health, Not Medication, Often Drives Neurodevelopmental Outcomes

Deciphering Prenatal Risks: Why Maternal Health, Not Medication, Often Drives Neurodevelopmental Outcomes

Recent large-scale cohort studies suggest that previously observed links between prenatal exposure to acid-suppressants or antipsychotics and neurodevelopmental disorders are largely due to familial confounding. Conversely, active maternal eating disorders remain a significant risk factor, highlighting the critical role of maternal health optimization.
ACT-Based Parenting Interventions Significantly Reduce Caregiver Stress and Improve Child Outcomes in Autism Spectrum Disorder

ACT-Based Parenting Interventions Significantly Reduce Caregiver Stress and Improve Child Outcomes in Autism Spectrum Disorder

A randomized clinical trial demonstrates that an 8-week Acceptance and Commitment Therapy (ACT) program significantly reduces parental stress and improves psychological flexibility and parenting competence, while also yielding positive secondary benefits for children's emotional and behavioral health over a 6-month period.
Scalable Success: Electronic Patient-Managed Interventions Significantly Drive Benzodiazepine Cessation

Scalable Success: Electronic Patient-Managed Interventions Significantly Drive Benzodiazepine Cessation

The EMPOWER-ED randomized clinical trial demonstrates that an electronic, patient-centered intervention significantly increases the odds of complete benzodiazepine cessation among long-term users, providing a scalable, low-cost solution for health systems to address benzodiazepine dependence without increasing clinician burden.
Music Therapy Proves Noninferior to Cognitive Behavioral Therapy for Managing Anxiety in Cancer Survivors: Results from a Randomized Trial

Music Therapy Proves Noninferior to Cognitive Behavioral Therapy for Managing Anxiety in Cancer Survivors: Results from a Randomized Trial

A randomized clinical trial demonstrates that telehealth-delivered music therapy is noninferior to cognitive behavioral therapy for reducing anxiety in cancer survivors, providing durable, clinically meaningful improvements and a viable alternative to traditional psychological interventions.
The Hidden Burden of Heart and Brain Health: ASCVD Linked to Significantly Elevated Suicide Risk

The Hidden Burden of Heart and Brain Health: ASCVD Linked to Significantly Elevated Suicide Risk

A large-scale nationwide study reveals that individuals with atherosclerotic cardiovascular disease (ASCVD), including myocardial infarction and stroke, face a 43% higher risk of suicide. The risk nearly doubles for those suffering from both conditions, highlighting an urgent need for mental health integration in cardiovascular care.
Beyond Picky Eating: Large-Scale Study Reveals the Genetic Architecture and Developmental Impact of ARFI Phenotypes

Beyond Picky Eating: Large-Scale Study Reveals the Genetic Architecture and Developmental Impact of ARFI Phenotypes

This large-scale study of 35,751 children characterizes ARFI phenotypes, revealing a 6.3% clinical prevalence and significant genetic heritability. Findings link ARFI to the ADCY3 locus and long-term neurodevelopmental difficulties, emphasizing the need for early identification and broad support interventions.
Neuropsychiatric Interaction with Vascular Health: Deciphering the Moderating Role of PTSD in Hormonal Contraceptive-Associated Cardiovascular Risk

Neuropsychiatric Interaction with Vascular Health: Deciphering the Moderating Role of PTSD in Hormonal Contraceptive-Associated Cardiovascular Risk

A large-scale cohort study demonstrates that while hormonal contraceptives are generally associated with lower cardiovascular risk in women, this protective effect is lost in those with PTSD, highlighting a critical intersection between psychiatric health and reproductive medicine.
Digital Phenotyping in Insomnia: Real-Time Smartphone Assessment Detects Daytime Benefits of Suvorexant Missed by Traditional Scales

Digital Phenotyping in Insomnia: Real-Time Smartphone Assessment Detects Daytime Benefits of Suvorexant Missed by Traditional Scales

A randomized clinical trial demonstrates that smartphone-based ecological momentary assessment (EMA) is significantly more sensitive than retrospective questionnaires in detecting the daytime clinical benefits of suvorexant, particularly regarding fatigue and subjective cognition in older adults with chronic insomnia.