Specialties – Page 73

Impact of Antibiotics, Steroids, and PPIs on Survival in Advanced NSCLC Patients Treated with First-Line Pembrolizumab

By MedXY 09/24/2025

This nationwide cohort study reveals that certain antibiotics, higher-dose steroids, and proton pump inhibitors are associated with reduced overall survival in advanced NSCLC patients receiving first-line pembrolizumab, underscoring the importance of careful comedication monitoring during immunotherapy.

Clinical Updates Neurology Pediatrics Specialties

Modifiable Parental Factors Influence Adolescent Sleep

By MedXY 09/24/2025

This prospective cohort study identifies modifiable parental factors linked to adolescent sleep outcomes over 4 years, highlighting the mediating roles of screen use and emotional regulation and sex-specific effects, with implications for interventions targeting adolescent sleep health.

Clinical Updates news Pediatrics Psychiatry Specialties

Childhood Loneliness: A Lasting Risk Factor for Cognitive Decline and Dementia in Later Life

By MedXY 09/24/2025

Childhood loneliness significantly increases the risk of cognitive decline and dementia in middle-aged and older adults, independent of adult loneliness, highlighting the importance of early psychosocial interventions.

Allergy & Immunology Clinical Updates OB/GYN & Women's Health

Pregnancy and Disease Outcomes in Women with Moderate to Severe Multiple Sclerosis Disability

By MedXY 09/24/2025

This study evaluates how pregnancy affects relapse rates and long-term disability in women with moderate to severe multiple sclerosis (MS), showing pregnancy reduces relapse during gestation without worsening long-term disability progression.

news OB/GYN & Women's Health Oncology Specialties

Impact of Treatment Recommendation and Receipt on Survival in Older Women with Early-Stage Cervical Cancer

By MedXY 09/24/2025

This study reveals that among women aged 65 and older with early-stage cervical cancer, those who receive recommended treatment—surgery and/or radiotherapy—exhibit significantly higher survival rates, emphasizing the need to overcome treatment barriers in this population.

Clinical Updates Neurology news OB/GYN & Women's Health Specialties

Sleep Disorders in Pregnancy: Unveiling Their Impact on Ischemic Placental Disease and Severe Morbidity

By MedXY 09/24/2025

Pregnant individuals with insomnia or obstructive sleep apnea face significantly increased risks of ischemic placental disease, severe maternal morbidity, and preterm birth, highlighting the critical need for early detection and intervention.

General Surgery news Oncology Specialties

Optimizing Treatment Selection for Hepatocellular Carcinoma: Machine Learning Guidance in Choosing Liver Transplantation versus Surgical Resection

By MedXY 09/23/2025

A machine learning model accurately stratifies patients with hepatocellular carcinoma to guide individualized selection between liver transplantation and surgical resection, improving survival outcomes while addressing donor scarcity and patient heterogeneity.

Family Medicine & Nutrition news Specialties

The Curious Scent of Feces: The Dual Identity and Health Secrets of Skatole

By MedXY 09/23/2025

Explore skatole, a compound with a paradoxical aroma found in feces and perfumes, its role in gut health, disease indicators, and diverse applications from medicine to agriculture.

Neurology news Specialties

Long-Term Outcomes in Critically Ill Adults With Acute Encephalitis: Insights From a Multicenter French Cohort

By MedXY 09/23/2025

A prospective study of 310 ICU patients with acute encephalitis reveals that half suffer moderate to severe disability or death at 3 months. Autoimmune encephalitis patients show notable recovery over one year, highlighting the need for tailored long-term support.

news Pediatrics Psychiatry Specialties

Brain Connectome Modulates the Impact of Adverse Childhood Experiences on Mental Health in Preadolescents

By MedXY 09/23/2025

This cohort study reveals that whole-brain functional connectivity alters the link between adverse childhood experiences and psychiatric disorders in children, particularly for threat-related exposures and females, suggesting a neurobiological basis of resilience in youth.

Medical News news Psychiatry Specialties

Linking Alcohol Consumption Per Capita to Suicide Mortality: Insights from a Meta-Analysis

By MedXY 09/23/2025

A meta-analysis found a population-level association between increased per capita alcohol consumption and higher suicide mortality, without sex differences, suggesting alcohol reduction as a vital component in suicide prevention.

Family Medicine & Nutrition Medical News Public Health Specialties

Consumer Misinterpretation of Dietary Supplement Labels: Implications for Public Health and Regulation

By MedXY 09/23/2025

Consumers frequently misconstrue dietary supplement labels with structure/function claims as implying disease prevention or treatment benefits, underscoring the need for clearer regulatory standards to prevent misinformation.

Clinical Updates Psychiatry Public Health Specialties

Unveiling the Burden and Trajectories of Perinatal Anxiety and Depression in a Major Urban Medical Center

By MedXY 09/23/2025

A retrospective study identifies critical gaps in screening and treatment of perinatal anxiety and depression, revealing prevalence rates, symptom trajectories, and the impact of mental health services in 3051 women.

Clinical Updates OB/GYN & Women's Health

Influence of Physician Peer Networks on the Adoption of Opportunistic Salpingectomy for Ovarian Cancer Prevention

By MedXY 09/23/2025

Physician peer influence significantly increases the adoption of opportunistic salpingectomy during postpartum and interval tubal sterilizations, enhancing ovarian cancer prevention.

Anesthesiology Clinical Updates Critical Care news

Clotting Factor Concentrates vs Frozen Plasma in Severe Trauma Resuscitation: Insights from the FiiRST-2 Randomized Trial

By MedXY 09/23/2025

The FiiRST-2 trial found no superiority of clotting factor concentrates over frozen plasma for initial resuscitation in severely bleeding trauma patients, with similar transfusion needs and safety outcomes.

Medical News Public Health

The Silent Threat of Chagas Disease: Understanding the ‘Kissing Bug’ Epidemic in the U.S.

By MedXY 09/23/2025

Chagas disease, spread by the 'kissing bug,' is emerging as a hidden health threat in the U.S. Understanding its transmission, symptoms, and prevention is key to curbing this neglected tropical disease's growing impact.

Clinical Updates news Psychiatry

Ammoxetine Shows Promise as Effective and Well-Tolerated Treatment for Major Depressive Disorder: Insights from a Phase 2 Randomized Trial

By MedXY 09/23/2025

A phase 2 trial in adults with major depressive disorder demonstrated that ammoxetine at 40 mg/d and 60 mg/d significantly improved depressive symptoms compared to placebo and was generally well tolerated, offering a novel treatment option with potentially fewer adverse effects.

Family Medicine & Nutrition Internal Medicine news Specialties

Challenges and Insights in Sustaining Weight Loss: Evaluating Adaptive vs Static Support

By MedXY 09/23/2025

A recent trial comparing adaptive, algorithm-driven telephone support with static monthly coaching found no significant difference in long-term weight loss maintenance, highlighting complexities in obesity treatment and the need for refined, patient-centered interventions.

Clinical Updates news Psychiatry

Evaluating the Patient Health Questionnaire-15 and Somatic Symptom Scale-8: Insights from a Systematic Review and Meta-Analysis

By MedXY 09/23/2025

This article critically reviews measurement properties of the PHQ-15 and SSS-8, two key instruments assessing somatic symptom burden, highlighting reliability, validity, and clinical applicability based on meta-analyzed evidence from over 300 studies.

Cardiology Clinical Updates

Evaluating Aspirin-Free Therapy Versus Dual Antiplatelet Treatment Post-Coronary Stenting: Insights from the STOPDAPT-3 Trial

By MedXY 09/23/2025

The STOPDAPT-3 randomized trial compared aspirin-free low-dose prasugrel monotherapy with standard dual antiplatelet therapy, revealing noninferior cardiovascular outcomes but no reduction in major bleeding after PCI, with signals of increased coronary events in the aspirin-free group.