Specialties – Page 59

Global Health Landscape 1990-2023: Insights from the Global Burden of Disease Study 2023

By MedXY 10/19/2025

This systematic analysis of the GBD 2023 presents global trends in disease burden, risk factors, and healthy life expectancy across 204 countries, elucidating shifts in NCDs, CMNN diseases, injuries, and underlying risk drivers crucial for guiding future health policy.

Gastroenterology Internal Medicine Specialties

Comparative Risks of MASLD and MetALD: Insights from a Comprehensive Meta-Analysis on Hepatic and Extrahepatic Outcomes

By MedXY 10/19/2025

This meta-analysis reveals that MetALD confers higher risks of liver-related events, hepatocellular carcinoma, and extrahepatic cancers compared to MASLD, while mortality and cardiovascular risks are similar, emphasizing tailored clinical approaches.

Diabetes & Endocrinology news Public Health Specialties

Bridging the Gaps in Global Diabetes Care: Insights from Two Decades of the Global Burden of Disease Study

By MedXY 10/19/2025

A comprehensive analysis reveals ongoing challenges in diabetes diagnosis, treatment, and glycaemic control worldwide, highlighting the urgent need for enhanced care strategies, especially in low- and middle-income regions.

Diabetes & Endocrinology Specialties

Enhanced Weight Reduction with Once-Weekly Semaglutide 7.2 mg in Obesity Management: Insights from the STEP UP Phase 3b Trial

By MedXY 10/18/2025

The STEP UP trial demonstrates that once-weekly semaglutide 7.2 mg significantly improves weight loss outcomes versus 2.4 mg and placebo in adults with obesity, with a manageable safety profile.

Infectious Diseases Neurology news

Emerging Threat: Active West Nile Virus Transmission in Brazil Reveals Critical Public Health Challenge

By MedXY 10/18/2025

Recent evidence confirms active West Nile virus transmission across Brazil with significant neurological impact and fatalities, emphasizing the need for enhanced surveillance and public health action in South America.

Hematology-Oncology OB/GYN & Women's Health Specialties

Ki-67 Dynamics During Neoadjuvant Chemotherapy: A Key to Better Breast Cancer Prognosis

By MedXY 10/18/2025

This study highlights the prognostic significance of tumor Ki-67 changes during neoadjuvant treatment, offering potential for improved risk stratification and personalized therapy in breast cancer patients.

Internal Medicine Oncology Specialties

Real-World Insights into HER2-Positive Metastatic Breast Cancer Treatments: Comparing T-DXd, T-DM1, and Tucatinib

By MedXY 10/18/2025

This study uses real-world data to compare the effectiveness and safety of trastuzumab deruxtecan versus trastuzumab emtansine and tucatinib in HER2-positive metastatic breast cancer, confirming their clinical value.

Psychiatry Public Health Specialties

Early Adolescent Mental Well-Being as a Predictor of Long-Term Health Outcomes

By MedXY 10/18/2025

This study highlights how poor mental well-being during adolescence predicts increased risks of mental illness, risky behaviors, and mortality in young adulthood, emphasizing the urgency for early identification and intervention.

Gastroenterology Infectious Diseases news

Evaluating the Necessity of Live Microbes in Fecal Microbiota Transplantation for C. difficile Recurrence: Insights from a Non-Inferiority Trial

By MedXY 10/18/2025

This study investigates whether sterile lyophilised fecal filtrate is as effective as traditional donor stool in preventing recurrent C. difficile infection, highlighting the importance of live microbes in treatment efficacy.

Oncology Pediatrics Specialties

Long-Term Sequelae in Survivors of High-Risk Neuroblastoma: Insights from the Children’s Oncology Group Study

By MedXY 10/18/2025

This study reveals significant late effects in childhood neuroblastoma survivors, emphasizing the need for targeted long-term follow-up care based on treatment exposures.

General Surgery Infectious Diseases Specialties

Evaluating the Impact of a Perioperative Care Bundle on Surgical Site Infection Prevention After Abdominal Surgery: Insights from the EPO2CH Trial

By MedXY 10/18/2025

This comprehensive review explores the EPO2CH trial, which assessed a multi-component care bundle's effectiveness in reducing surgical site infections after abdominal surgery, highlighting key findings, limitations, and clinical implications.

Diabetes & Endocrinology Internal Medicine Specialties

Monlunabant Shows Promise for Weight Loss in Obesity and Metabolic Syndrome: A Phase 2A Trial Review

By MedXY 10/18/2025

This phase 2a trial demonstrates that monlunabant induces significant weight loss across various doses in obese adults with metabolic syndrome, with dose-dependent adverse events highlighting the need for further safety evaluation.

Internal Medicine Psychiatry Specialties

Comparative Effectiveness of Long-Acting Injectable Versus Oral Antipsychotics in Older Adults with Schizophrenia: Insights from Hong Kong’s Population-Based Study

By MedXY 10/18/2025

This study compares long-acting injectable to oral antipsychotics in older schizophrenia patients, highlighting benefits in relapse prevention and mortality reduction, with specific considerations for adverse effects.

Hematology-Oncology Specialties

Restrictive Treatment Criteria Improve Prognosis Prediction in Chronic Lymphocytic Leukemia: Insights from the Brazilian Registry

By MedXY 10/18/2025

A restrictive treatment initiation approach in CLL, endorsed by the Brazilian Group of CLL, identifies patients with higher risk more accurately and spares low-risk patients from unnecessary therapy, showing superior prognostic stratification compared to international guidelines.

OB/GYN & Women's Health Psychiatry Specialties

Evaluating the Effectiveness of Circle of Security-Parenting for Perinatal Mental Health: Insights from a Large-Scale RCT

By MedXY 10/18/2025

This study finds no significant benefit of the Circle of Security-Parenting intervention added to usual care for improving mental health and bonding among new parents in NHS settings.

Psychiatry Public Health Specialties

Rising Trends in Non-Lethal Self-Harm and Suicide in Spain (2018-2023): A Nationwide Registry Analysis with a Focus on Age and Gender

By MedXY 10/18/2025

A nationwide study in Spain from 2018 to 2023 reveals increasing rates of non-lethal intentional self-harm and suicide, particularly among young women, underscoring the need for targeted mental health interventions.

OB/GYN & Women's Health Oncology Specialties

Assessing the Nationwide Prevalence and Outcomes of Breast Cancer Patients Eligible for Adjuvant CDK4/6 Inhibitors

By MedXY 10/18/2025

This study offers insights into the prevalence, characteristics, and long-term survival of breast cancer patients eligible for adjuvant CDK4/6 inhibitors, highlighting real-world outcomes compared to clinical trial populations.

OB/GYN & Women's Health Psychiatry Specialties

Hyperemesis Gravidarum and Depression: Unveiling the Bidirectional Link

By MedXY 10/18/2025

This comprehensive review examines the recent Finnish study highlighting the complex relationship between hyperemesis gravidarum and depression, emphasizing clinical implications for integrated mental health screening during reproductive care.

Infectious Diseases Internal Medicine news

Deciphering the Impact of Resistance Genes on Antibiotic Efficacy in E. coli: Insights from a Comprehensive Study

By MedXY 10/18/2025

This study quantifies how specific resistance genes influence minimum inhibitory concentrations in E. coli, enhancing prediction accuracy for antibiotic resistance.

Oncology Respiratory

Advancing First-Line Treatment in Metastatic NSCLC: The Promise of Retifanlimab Combined with Chemotherapy

By MedXY 10/17/2025

This article reviews the phase 3 POD1UM-304 trial demonstrating that adding retifanlimab to platinum-based chemotherapy improves overall survival in first-line metastatic NSCLC, highlighting its potential as a new standard of care.