Congenital CMV in Australia: Reported Cases Are a Small Fraction of Estimated Burden — Implications for Screening, Treatment, and Public Health
Posted inInfectious Diseases news Pediatrics

Congenital CMV in Australia: Reported Cases Are a Small Fraction of Estimated Burden — Implications for Screening, Treatment, and Public Health

National APSU surveillance (1999–2024) found 479 definite congenital CMV cases and dramatic under-ascertainment versus expected prevalence; symptomatic infants increasingly receive antivirals. Expanded surveillance, newborn screening, and clear treatment pathways are needed.
Higher Early IV Fluid Rates Tied to More SIRS but Lower BUN Rise in Acute Pancreatitis: Findings From an International Cohort Presented at ACG 2025
Posted inCritical Care Gastroenterology news

Higher Early IV Fluid Rates Tied to More SIRS but Lower BUN Rise in Acute Pancreatitis: Findings From an International Cohort Presented at ACG 2025

An international prospective cohort found that higher early IV fluid rates were associated with lower odds of BUN rise but higher odds of new or persistent SIRS at 6 and 24 hours after presentation, highlighting confounding issues and the need to individualize resuscitation.
Unilateral Pediatric Chronic Otitis Media with Effusion Impairs Binaural Hearing and Raises Tinnitus Risk: Evidence Challenging Conservative Management
Posted innews Otorhinolaryngology Pediatrics

Unilateral Pediatric Chronic Otitis Media with Effusion Impairs Binaural Hearing and Raises Tinnitus Risk: Evidence Challenging Conservative Management

A prospective cross-sectional study finds unilateral chronic otitis media with effusion (COME) in children is associated with poorer spatial release from masking and high tinnitus prevalence, suggesting potential central auditory consequences that may warrant reappraisal of conservative treatment recommendations.
Obesity Alters Symptom Trajectory and Inflammatory Signatures after Sport-Related Concussion: the NCAA‑DoD CARE Consortium
Posted inDiabetes & Endocrinology Neurology news

Obesity Alters Symptom Trajectory and Inflammatory Signatures after Sport-Related Concussion: the NCAA‑DoD CARE Consortium

In a large prospective cohort, obese BMI (≥30) was associated with worse post-concussion neurocognitive outcomes and a persistently proinflammatory blood biomarker profile, despite fewer baseline symptoms. Findings suggest obesity modifies clinical recovery and biological response after sport-related concussion.
Red Blood Cell Metabolism Modulates Muscle Oxygenation and Limits Exercise Capacity: Insights from a Randomized Double‑Blind Crossover Study
Posted inInternal Medicine news

Red Blood Cell Metabolism Modulates Muscle Oxygenation and Limits Exercise Capacity: Insights from a Randomized Double‑Blind Crossover Study

A randomized crossover study in 20 men shows exercise‑induced oxidative stress alters erythrocyte redox and glycolytic metabolism, reduces 2,3‑BPG/ATP generation, and modestly impairs muscle oxygen extraction and arm exercise VO2peak, suggesting erythrocyte metabolism can influence exercise performance.
Ankle and Knee Dominance, Female Vulnerability, and Game-Time Risk: Contemporary Injury Incidence in Basketball Players
Posted innews Orthopedics Public Health

Ankle and Knee Dominance, Female Vulnerability, and Game-Time Risk: Contemporary Injury Incidence in Basketball Players

Systematic review and meta-analysis of 22 studies finds player contact and non-contact mechanisms dominate; ankle (25.8%) and knee (15.5%) injuries account for 41% of injuries. Females have higher rates of knee, concussion, and ball-contact injuries; injury rates are higher in games and at collegiate level.
Neuromuscular Training Substantially Improves Athletes’ Balance: A Meta-Analysis with Practical Takeaways
Posted inNeurology news Orthopedics Public Health

Neuromuscular Training Substantially Improves Athletes’ Balance: A Meta-Analysis with Practical Takeaways

A 2025 meta-analysis of 13 trials found neuromuscular training produced large improvements in athletes' balance (overall SMD 1.47), with benefits for both static and dynamic domains. Results support incorporating targeted neuromuscular programs into conditioning, while highlighting heterogeneity and research gaps.
Urolithin A in Elite Distance Runners: Improves Recovery and Perceived Effort but Not Race Performance in 4-Week Altitude Training
Posted inInternal Medicine news Public Health

Urolithin A in Elite Distance Runners: Improves Recovery and Perceived Effort but Not Race Performance in 4-Week Altitude Training

A randomized, placebo-controlled trial in highly trained male distance runners found 4 weeks of 1000 mg/day urolithin A reduced markers of muscle damage and perceived exertion and upregulated mitochondrial proteomic pathways, but did not produce statistically significant performance gains in a 3000 m time trial.
Hearing Aids Improve Some Aspects of Socio-Emotional Well‑being — But Not All: Insights from the WHAM Longitudinal Study
Posted innews Otorhinolaryngology

Hearing Aids Improve Some Aspects of Socio-Emotional Well‑being — But Not All: Insights from the WHAM Longitudinal Study

The WHAM longitudinal study finds modest psychosocial benefits from hearing‑aid uptake—reduced depression in people without tinnitus and lower loneliness in older adults—while showing limited mediation by self-perceived hearing disability and minimal effects of use duration or daily wearing hours.