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Understanding the Safe and Fertile Periods in a Woman’s Menstrual Cycle
Posted innews OB/GYN & Women's Health Specialties

Understanding the Safe and Fertile Periods in a Woman’s Menstrual Cycle

Posted by By MedXY 08/07/2025
This article explains the timing of safe and fertile periods in the menstrual cycle to aid women in contraception and pregnancy planning.
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Understanding Reddish-Brown Discharge After Orgasm: Causes and Care
Posted innews OB/GYN & Women's Health Specialties

Understanding Reddish-Brown Discharge After Orgasm: Causes and Care

Posted by By MedXY 08/07/2025
Explore the physiological and pathological reasons behind reddish-brown discharge after orgasm and learn practical steps for maintaining reproductive health.
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The Impact of Female Orgasm on Ovarian Health: Insights into Early Ovarian Aging
Posted innews OB/GYN & Women's Health Specialties

The Impact of Female Orgasm on Ovarian Health: Insights into Early Ovarian Aging

Posted by By MedXY 08/07/2025
Exploring the potential connection between female orgasms and ovarian health, this article delves into the role of hormonal balance, circulation, and overall well-being in preventing early ovarian aging.
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Understanding Safe Periods: How to Calculate and Navigate Them Effectively
Posted innews OB/GYN & Women's Health Specialties

Understanding Safe Periods: How to Calculate and Navigate Them Effectively

Posted by By MedXY 08/07/2025
Learn the science behind calculating safe periods based on the menstrual cycle, common misconceptions, and practical steps for effective family planning.
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When Do Thyroid Nodules Require Surgery? Clear Answers Here
Posted inGeneral Surgery news Specialties

When Do Thyroid Nodules Require Surgery? Clear Answers Here

Posted by By MedXY 08/07/2025
Thyroid nodules larger than 4 cm often require surgery due to potential compression of surrounding tissues, but smaller nodules with signs of malignancy or symptoms may also need surgical intervention. This article explains the criteria in detail.
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Understanding the Differences Between Breast Hyperplasia and Breast Nodules
Posted inMedical News news OB/GYN & Women's Health Specialties

Understanding the Differences Between Breast Hyperplasia and Breast Nodules

Posted by By MedXY 08/07/2025
This article provides an in-depth comparison of breast hyperplasia and breast nodules, highlighting their definitions, symptoms, causes, diagnostic methods, and treatment options.
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Understanding Ovulation Bleeding: Normal or a Sign of Disease?
Posted inMedical News news OB/GYN & Women's Health Specialties

Understanding Ovulation Bleeding: Normal or a Sign of Disease?

Posted by By MedXY 08/07/2025
Explore the causes, symptoms, and implications of ovulation bleeding, distinguishing between normal physiological occurrences and potential health concerns.
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Three Diseases to Watch for When Experiencing Shoulder Pain: Don’t Mistake These Pain Locations for Frozen Shoulder
Posted innews Orthopedics Specialties

Three Diseases to Watch for When Experiencing Shoulder Pain: Don’t Mistake These Pain Locations for Frozen Shoulder

Posted by By MedXY 08/07/2025
Shoulder pain is often attributed to frozen shoulder, but cervical spondylosis, cholecystitis, and heart disease can also cause shoulder pain. Correct diagnosis is crucial to avoid treatment delays and complications.
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Understanding Brown Discharge After Intimacy: Causes and When to Seek Help
Posted innews Orthopedics Specialties

Understanding Brown Discharge After Intimacy: Causes and When to Seek Help

Posted by By MedXY 08/07/2025
Explore the causes of brown vaginal discharge after sexual activity, distinguishing between normal physiological responses and potential health concerns.
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White Clumpy Vaginal Discharge? It Could Be These 3 Common Gynecological Issues!
Posted innews OB/GYN & Women's Health Specialties

White Clumpy Vaginal Discharge? It Could Be These 3 Common Gynecological Issues!

Posted by By MedXY 08/07/2025
White clumpy vaginal discharge can signal common gynecological conditions like yeast infections, bacterial vaginosis, or normal physiological changes. Understanding symptoms and seeking appropriate care is crucial for women's health.
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Daratumumab Plus VTd Induction and Maintenance: Transforming Outcomes in Newly Diagnosed Multiple Myeloma—Long-Term MRD and PFS Insights from CASSIOPEIA
Posted inClinical Updates Hematology-Oncology news Specialties

Daratumumab Plus VTd Induction and Maintenance: Transforming Outcomes in Newly Diagnosed Multiple Myeloma—Long-Term MRD and PFS Insights from CASSIOPEIA

Posted by By MedXY 08/07/2025
Long-term CASSIOPEIA results confirm daratumumab plus VTd induction/consolidation and daratumumab maintenance deliver deepest MRD negativity and superior PFS in transplant-eligible, newly diagnosed myeloma.
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Venetoclax in Relapsed/Refractory Multiple Myeloma: Balancing Disease Control and Survival—Final Results from the BELLINI Phase 3 Trial
Posted inClinical Updates Hematology-Oncology news Specialties

Venetoclax in Relapsed/Refractory Multiple Myeloma: Balancing Disease Control and Survival—Final Results from the BELLINI Phase 3 Trial

Posted by By MedXY 08/07/2025
Final BELLINI trial results show improved progression-free survival with venetoclax in relapsed/refractory multiple myeloma, but increased early mortality negates overall survival benefit, prompting caution for general use.
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Olverembatinib Plus Venetoclax and Reduced-Intensity Chemotherapy: A Promising New Frontier for Adult Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia
Posted inClinical Updates Hematology-Oncology news Specialties

Olverembatinib Plus Venetoclax and Reduced-Intensity Chemotherapy: A Promising New Frontier for Adult Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

Posted by By MedXY 08/07/2025
A phase 2 trial shows that olverembatinib combined with venetoclax and reduced-intensity chemotherapy achieves high molecular response and survival rates in newly diagnosed Ph+ ALL patients, offering a less intensive alternative.
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Surgery or Radiofrequency Ablation for Small Hepatocellular Carcinoma: Insights from the SURF Trials
Posted inClinical Updates General Surgery news Oncology Radiology Specialties

Surgery or Radiofrequency Ablation for Small Hepatocellular Carcinoma: Insights from the SURF Trials

Posted by By MedXY 08/07/2025
The SURF trials found no significant difference in survival or recurrence-free outcomes between surgery and radiofrequency ablation for small hepatocellular carcinoma, supporting RFA as a less invasive, equally effective option.
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First-Line Camizestrant for ESR1-Mutated Advanced Breast Cancer: Redefining Endocrine Therapy Resistance
Posted inClinical Updates news OB/GYN & Women's Health Oncology Specialties

First-Line Camizestrant for ESR1-Mutated Advanced Breast Cancer: Redefining Endocrine Therapy Resistance

Posted by By MedXY 08/07/2025
Next-generation SERD camizestrant significantly prolongs progression-free survival over aromatase inhibitors or fulvestrant in ESR1-mutated, ER-positive, HER2-negative advanced breast cancer, with favorable safety and quality-of-life profiles.
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Vepdegestrant: A Next-Generation Oral PROTAC ER Degrader for Advanced ER+/HER2– Breast Cancer—VERITAC-2 Results and Clinical Implications
Posted inClinical Updates news OB/GYN & Women's Health Oncology Specialties

Vepdegestrant: A Next-Generation Oral PROTAC ER Degrader for Advanced ER+/HER2– Breast Cancer—VERITAC-2 Results and Clinical Implications

Posted by By MedXY 08/07/2025
Vepdegestrant, an oral PROTAC estrogen receptor degrader, significantly prolongs progression-free survival compared to fulvestrant in ESR1-mutant advanced breast cancer, but not in the overall ER+/HER2– population.
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Reduced Elective Radiotherapy Dose in Head and Neck Cancer: New Evidence from the UPGRADE-RT Trial
Posted inClinical Updates news Oncology Radiology Specialties

Reduced Elective Radiotherapy Dose in Head and Neck Cancer: New Evidence from the UPGRADE-RT Trial

Posted by By MedXY 08/07/2025
The UPGRADE-RT multicenter trial confirms that lowering elective neck irradiation dose in definitive radiotherapy for head and neck cancer maintains disease control and improves quality of life, reducing toxicity without increasing recurrence risk.
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Timing Matters: Sequential Pembrolizumab Plus Chemoradiation Outperforms Concurrent Approach in Locally Advanced Head and Neck Cancer
Posted inClinical Updates news Oncology Specialties

Timing Matters: Sequential Pembrolizumab Plus Chemoradiation Outperforms Concurrent Approach in Locally Advanced Head and Neck Cancer

Posted by By MedXY 08/07/2025
A Phase II trial finds sequential pembrolizumab after chemoradiation achieves superior locoregional control compared to concurrent administration in locally advanced head and neck squamous cell carcinoma.
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Long-Term Outcomes of Transoral Surgery with Risk-Adapted Adjuvant Therapy in HPV-Positive Oropharyngeal Cancer: Results from the E3311 Trial
Posted inClinical Updates General Surgery news Oncology Specialties

Long-Term Outcomes of Transoral Surgery with Risk-Adapted Adjuvant Therapy in HPV-Positive Oropharyngeal Cancer: Results from the E3311 Trial

Posted by By MedXY 08/07/2025
The E3311 phase II trial shows excellent long-term survival with deintensified postoperative management after transoral surgery in HPV-associated oropharyngeal cancer, with most patients spared from high-dose radiation and chemotherapy.
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Triplet Therapy Advances: Azacitidine, Venetoclax, and Revumenib in Newly Diagnosed NPM1-Mutated or KMT2A-Rearranged AML
Posted inClinical Updates Hematology-Oncology news Specialties

Triplet Therapy Advances: Azacitidine, Venetoclax, and Revumenib in Newly Diagnosed NPM1-Mutated or KMT2A-Rearranged AML

Posted by By MedXY 08/07/2025
A phase I trial demonstrates high remission rates and manageable safety for azacitidine, venetoclax, and revumenib in older adults with newly diagnosed NPM1-mutated or KMT2A-rearranged AML, offering new hope for these high-risk patients.
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  • AL-ISS: A New Staging System Identifies an Ultra‑Poor‑Risk Stage (IIIC) in Contemporary AL Amyloidosis
  • Pirtobrutinib Matches and May Surpass Ibrutinib in BTKi‑Naïve CLL/SLL: First Randomized Head‑to‑Head Results with Improved Cardiac Safety
  • Postoperative ctDNA Identifies Stage III Colon Cancer Patients Who May Benefit from Adjuvant Celecoxib
  • No Net Benefit from Adding Antiplatelet Therapy to Anticoagulation After Ischemic Stroke With Atrial Fibrillation and Atherosclerosis — Higher Bleeding Risk
  • Lower Posttreatment Amyloid Predicts Slower Clinical Decline and Reduced Tau/Glial Biomarkers After Donanemab: Secondary Analysis of TRAILBLAZER‑ALZ 2
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