Butyrate-Producing Clostridium butyricum: A Direct Interactor with Colorectal Cancer Cells that Reverses Immune Suppression and Enhances Checkpoint Inhibitor Efficacy
Posted inClinical Updates Family Medicine & Nutrition Gastroenterology news Oncology Specialties

Butyrate-Producing Clostridium butyricum: A Direct Interactor with Colorectal Cancer Cells that Reverses Immune Suppression and Enhances Checkpoint Inhibitor Efficacy

Recent research uncovers that the probiotic Clostridium butyricum directly interacts with colorectal cancer cells to inhibit immune suppression via the secD-GRP78 axis, restoring CD8+ T cell antitumor function and enhancing PD-1 inhibitor therapy.
Long-term Ambient Air Pollution Exposure and Asthma Exacerbation Risk in Women: Evidence from the Nurses’ Health Study II
Posted inAllergy & Immunology Family Medicine & Nutrition news Respiratory Specialties

Long-term Ambient Air Pollution Exposure and Asthma Exacerbation Risk in Women: Evidence from the Nurses’ Health Study II

Long-term exposure to ambient air pollutants, notably nitrogen dioxide, is linked to increased asthma exacerbations in women, independent of plant-based diet adherence, underscoring the need for stricter air quality standards and targeted resilience strategies.
Clinical Therapeutic Value of Curcumin Supplementation in Cardiovascular Disease, Diabetes, Cognitive Function, Aging, and Neurodegenerative Disorders: A Synthesis of Recent Evidence
Posted inCardiology Diabetes & Endocrinology Family Medicine & Nutrition Neurology news Specialties

Clinical Therapeutic Value of Curcumin Supplementation in Cardiovascular Disease, Diabetes, Cognitive Function, Aging, and Neurodegenerative Disorders: A Synthesis of Recent Evidence

Current evidence supports curcumin supplementation for reducing cardiovascular risk factors and preventing type 2 diabetes progression, with emerging potential in cognitive decline and aging-related degenerative diseases.
Protective Effects of High-Intensity Interval Training on Cardiovascular, Neurological, and Metabolic Health: An Evidence-Based Review
Posted inCardiology Diabetes & Endocrinology Family Medicine & Nutrition Neurology Specialties

Protective Effects of High-Intensity Interval Training on Cardiovascular, Neurological, and Metabolic Health: An Evidence-Based Review

This review synthesizes recent evidence demonstrating that high-intensity interval training (HIIT) confers cardiometabolic benefits, modulates microvascular and neural function, enhances insulin sensitivity, and improves mental health outcomes, underscoring its potential as a multifaceted therapeutic strategy.