Cardiology – Medxy AI

Long-Term Stroke Risk in Healthy Women: The Predictive Role of hsCRP, LDL Cholesterol, and Lipoprotein(a)

By MedXY 10/22/2025

A 30-year prospective study reveals that elevated hsCRP, LDL cholesterol, and lipoprotein(a) levels independently and collectively increase the risk of ischaemic stroke in healthy women, advocating for early biomarker screening in stroke prevention.

Cardiology Family Medicine & Nutrition Specialties

Optimizing Food Insecurity Interventions to Lower Blood Pressure: Insights from the Healthy Food First Trial

By MedXY 10/21/2025

A factorial RCT in food-insecure adults with hypertension found that healthy food subsidies modestly reduced blood pressure compared with delivered food boxes, while lifestyle counseling and longer duration showed no added benefit.

Cardiology news Public Health

Active Monitoring for Atrial Fibrillation (AMALFI): Advancing Long-Term Remote Screening to Reduce Stroke Risk

By MedXY 10/21/2025

The AMALFI trial evaluates remote screening for asymptomatic atrial fibrillation in older adults to improve detection, anticoagulation use, and reduce stroke risk, with findings pending follow-up at 2.5 and 5 years.

Cardiology news Public Health

Remote ECG Patch Screening for Asymptomatic Atrial Fibrillation: Insights from the AMALFI Trial

By MedXY 10/21/2025

The AMALFI trial demonstrates that remote, mail-based 14-day ECG patch screening modestly increases long-term atrial fibrillation detection and anticoagulation use in older adults at stroke risk, with no observed reduction in stroke at 2.5 years.

Cardiology Pediatrics Specialties Transplantation

Everolimus and Low-Dose Tacrolimus Therapy After Pediatric Heart Transplant: Insights from a Multicenter Randomized Clinical Trial

By MedXY 10/21/2025

This randomized trial evaluates the safety and efficacy of everolimus combined with low-dose tacrolimus versus standard immunosuppression in children 6 months post-heart transplant, highlighting comparable rejection rates, improved kidney function, and reduced CMV infection risk.

Cardiology Neurology news Specialties

Obicetrapib’s Role in Modulating Alzheimer’s Disease Biomarkers in Patients with Cardiovascular Disease: A Landmark Clinical Study

By MedXY 10/21/2025

Obicetrapib, a CETP inhibitor, lowers Alzheimer’s biomarkers like p-tau217 in ASCVD patients, especially ApoE4 carriers, suggesting a potential preventive strategy for high-risk individuals.

Cardiology Family Medicine & Nutrition news Specialties

Dietary Patterns and Intracranial Atherosclerosis Risk in Elderly Patients With Hypertension or Myocardial Infarction: An Evidence-Based Review

By MedXY 10/21/2025

Healthy dietary patterns may reduce intracranial atherosclerosis severity in older adults with hypertension or prior myocardial infarction, suggesting diet's conditional protective role in vascular brain disease.

Cardiology Nephrology Specialties

Statin Therapy in Older Adults with Chronic Kidney Disease: Primary Prevention of Cardiovascular Disease and Safety Profile in Hypercholesterolemic Patients

By MedXY 10/20/2025

This study demonstrates that statin therapy effectively reduces cardiovascular risk and all-cause mortality in older adults with chronic kidney disease and hypercholesterolemia, without increasing major adverse events, even in very elderly patients.

Cardiology news Oncology

Impacts of Plant-Based Diets on Multimorbidity Risk in Cancer and Cardiometabolic Diseases Across Age Groups

By MedXY 10/20/2025

This analysis of EPIC and UK Biobank cohorts reveals that healthy plant-based diets reduce multimorbidity risk of cancer and cardiometabolic diseases, especially in middle-aged adults, underscoring diet's role in chronic disease prevention and management.

Cardiology Nephrology news

Integrating Triglyceride-Glucose Indices with Obesity Measures Enhances Cardiovascular and Mortality Risk Prediction in CKM Syndrome

By MedXY 10/19/2025

This study demonstrates that triglyceride-glucose-related indices combined with obesity measures significantly predict cardiovascular outcomes and mortality in individuals with cardiovascular-kidney-metabolic syndrome stages 0-3, offering improved prognostic utility.

Cardiology Diabetes & Endocrinology news

Impact of Diabetes on the Triglyceride-Glucose Index and Cardiovascular Outcomes in Coronary Heart Disease: A Comprehensive Meta-Analysis

By MedXY 10/19/2025

This meta-analysis of 36 cohort studies shows that higher triglyceride-glucose index levels predict increased risk of major adverse cardiovascular events in coronary heart disease patients, with differential effects observed by diabetes status.

Cardiology Diabetes & Endocrinology Specialties

Triglyceride Glucose-Waist Height Ratio Index as a Predictor of Cardiometabolic Multimorbidity in Chinese Middle-Aged and Older Adults: Insights from a National Prospective Cohort Study

By MedXY 10/19/2025

This study demonstrates that the triglyceride glucose-waist height ratio (TyG-WHtR) index independently predicts cardiometabolic multimorbidity risk in Chinese adults aged ≥45, showing a linear dose-response relationship and improved predictive performance over traditional metrics.

Cardiology Diabetes & Endocrinology news

Joint Impact of TyG-Related Indices and eGDR on Cardiometabolic Multimorbidity Risk in Chinese Adults: Insights from a Nationwide Cohort

By MedXY 10/19/2025

This study elucidates that high triglyceride glucose (TyG) related indices combined with low estimated glucose disposal rate (eGDR) synergistically elevate cardiometabolic multimorbidity (CMM) risk in middle-aged and older Chinese adults, enhancing early risk stratification and prevention strategies.

Cardiology Diabetes & Endocrinology Nephrology news

Insulin Resistance Indices as Predictors of Cardio-Renal-Metabolic Multimorbidity: Insights from the UK Biobank

By MedXY 10/19/2025

This study demonstrates that insulin resistance indices, particularly TyG-WC, TyG-WHtR, and METS-IR, robustly predict the risk and progression of cardio-renal-metabolic multimorbidity, with inflammation and kidney function mediating these associations.

Cardiology Specialties

Enhanced GRACE 3.0 Score for Personalized Management of Non-ST-Elevation Acute Coronary Syndrome: Insights from a Multinational Validation Study

By MedXY 10/19/2025

The updated GRACE 3.0 scoring system improves mortality prediction and personalizes early invasive treatment decisions in non-ST-elevation acute coronary syndrome across ten countries, demonstrating excellent validation and clinical utility.

Cardiology Hematology-Oncology news

Clonal Hematopoiesis in Older Adults: Implications for Cardiovascular Risk, Bleeding, and Aspirin Use

By MedXY 10/15/2025

This study reveals that clonal hematopoiesis of indeterminate potential (CHIP) in adults aged 70+ does not increase cardiovascular risk but is associated with heightened bleeding risk. Aspirin showed no additional benefits or harms for those with CHIP in primary prevention of cardiovascular events.

Cardiology news

Dual Versus Single Antiplatelet Therapy After Valve-in-Valve TAVI: Balancing Stroke Prevention and Bleeding Risk

By MedXY 10/14/2025

This study compares dual and single antiplatelet therapy after valve-in-valve transcatheter aortic valve implantation, finding dual therapy reduces stroke risk without increasing bleeding or valve deterioration at one year.

Cardiology Specialties

CDKL1 Variants and Their Role in Thoracic Aortic Aneurysm and Dissection: Illuminating Cilia-Linked Pathogenesis

By MedXY 10/14/2025

This study identifies CDKL1 gene variants impairing ciliary function as novel genetic contributors to thoracic aortic aneurysm and dissection, highlighting an emerging pathogenic link between cilia biology and vascular disease.

Cardiology Family Medicine & Nutrition news Public Health

Harnessing Flavan-3-ols for Cardiovascular Health: Impacts on Blood Pressure and Endothelial Function

By MedXY 10/12/2025

This systematic review and meta-analysis demonstrates that flavan-3-ol-rich foods significantly lower blood pressure and improve endothelial function, supporting their role in cardiovascular prevention, especially in individuals with elevated or hypertensive baseline blood pressure.

Cardiology news

Long-Term Outcomes of Transcatheter Versus Surgical Aortic Valve Replacement: A Meta-Analysis of Time-to-Event Data

By MedXY 10/12/2025

This meta-analysis evaluates 5-year outcomes comparing TAVI and SAVR across risk profiles, revealing early advantages with TAVI that level off long-term, with no significant difference at 5 years.