Medxy AI

Enhanced Therapeutic Outcomes in Overweight/Obese Women with PCOS: Combining Metformin and Semaglutide

By MedXY 09/16/2025

Combination therapy with metformin and semaglutide improves weight loss, metabolic parameters, menstrual function, and natural pregnancy rates in overweight/obese women with PCOS compared to metformin alone.

$Phase Ib Trial of Metformin Combined with Nivolumab in Refractory Solid Tumors: Safety, Dosage, and Preliminary Efficacy$

Clinical Updates Wellness & Lifestyle

Phase Ib Trial of Metformin Combined with Nivolumab in Refractory Solid Tumors: Safety, Dosage, and Preliminary Efficacy

By MedXY 09/15/2025

A phase Ib study evaluated the safety, optimal dosing, pharmacokinetics, and preliminary efficacy of metformin with nivolumab in refractory solid tumors, showing good tolerability and promising responses in a subset of patients.

Clinical Updates Wellness & Lifestyle

Oral Metformin in Non-Muscle-Invasive Bladder Cancer: Insights from a Phase II Marker Lesion Study

By MedXY 09/15/2025

A phase II trial assessing oral metformin for low-grade non-muscle-invasive bladder cancer (NMIBC) found minimal antitumor activity and no significant mechanistic changes, challenging metformin’s role as an intravesical therapeutic agent in this context.

Clinical Updates Wellness & Lifestyle

Optimizing Anesthesia in Elderly NSCLC Patients: Impact of Midazolam and Dexmedetomidine Co-Administration on Hemodynamics and Stress Response

By MedXY 09/15/2025

Co-administering midazolam with dexmedetomidine in elderly NSCLC patients undergoing lobectomy enhances hemodynamic stability and reduces perioperative stress response, potentially improving recovery outcomes without increasing adverse events.

Medical News Wellness & Lifestyle

Why Do Chimpanzees Rarely Get Cancer? Unveiling a Key Evolutionary Difference That Could Revolutionize Immunotherapy

By MedXY 09/14/2025

New research reveals that a protein called plasmin weakens human immune response against cancer compared to chimpanzees, offering promising strategies to enhance cancer immunotherapy.

Medical News Wellness & Lifestyle

How Micronutrients Have Shaped Human DNA: Insights from Global Genetic Adaptations

By MedXY 09/14/2025

A recent study reveals how essential micronutrients like iron, calcium, and zinc influenced human evolution by driving genetic adaptations to environmental nutrient availability across populations worldwide.

Medical News Wellness & Lifestyle

Sudden Death Is Not So Sudden: Understanding, Preventing, and Responding to Cardiac Arrest

By MedXY 09/14/2025

Sudden death, often caused by heart conditions, is typically the culmination of gradual damage. This article explores warning signs, emergency response, and crucial prevention strategies to protect your heart and save lives.

Medical News Wellness & Lifestyle

The Ginger Miracle? Exploring the Anti-Aging Potential of Ginger and What the Science Really Says

By MedXY 09/14/2025

Recent studies suggest a compound in ginger may clear half of aging cells in two days, but practical benefits and safety concerns warrant cautious optimism. Here's a science-based look at ginger and aging.

Medical News Wellness & Lifestyle

Citrate: The New Molecular Key to Reversing Vascular Aging and Combating Cardiovascular Disease

By MedXY 09/14/2025

Recent research reveals that citrate, a natural compound found in citrus fruits, may significantly reverse vascular aging and reduce the risk of cardiovascular diseases by restoring mitochondrial function and vascular elasticity.

Clinical Updates Wellness & Lifestyle

Enhanced Gait Rehabilitation in Chronic Stroke: Combining High-Intensity Interval Training with Robot-Assisted Gait Therapy

By MedXY 09/14/2025

A randomized controlled trial demonstrates that combining high-intensity interval training with robot-assisted gait therapy significantly improves gait speed, balance, and lower limb function in patients with chronic stroke compared to treadmill therapy alone.

Clinical Updates Wellness & Lifestyle

Enhanced Adenoma Detection in Water Exchange Colonoscopy Using AI: Insights from a Two-Center Randomized Trial

By MedXY 09/14/2025

A multicenter trial demonstrated that integrating AI-based computer-aided detection with water exchange colonoscopy significantly increases adenomas per colonoscopy without prolonging procedure time or increasing non-neoplastic lesion detection.

Clinical Updates Wellness & Lifestyle

Advancing Clinical Care with AI Agents: Systematic Review of Performance and Integration in Medicine

By MedXY 09/14/2025

This review evaluates AI agent systems built on large language models in healthcare, demonstrating improved clinical task accuracy over base models, especially in complex scenarios. Multi-agent architectures show promise but require further real-world validation.

Medical News Wellness & Lifestyle

Do Active People Really Live Longer? Twin Study Reveals the Complex Truth About Exercise, Aging, and Longevity

By MedXY 09/14/2025

A decades-long twin study reveals that while exercise is linked to longevity, genetics and baseline health play a crucial role, and the relationship between exercise and aging follows a U-shaped curve.

Clinical Updates Wellness & Lifestyle

Evaluating AI-Enhanced EMG Reporting: Insights from a Randomized Controlled Trial

By MedXY 09/14/2025

An RCT evaluated an AI-assisted framework for electrodiagnostic report interpretation, finding no significant improvement over standard physician reporting but highlighting potential workflow benefits for routine cases.

Clinical Updates Wellness & Lifestyle

Harnessing AI for Personalized Depression Treatment: Insights from the AID-ME Cluster Randomized Trial

By MedXY 09/14/2025

The AID-ME trial demonstrates that an AI-powered clinical decision support system significantly improves remission rates and accelerates symptom improvement in moderate to severe major depressive disorder.

Clinical Updates Wellness & Lifestyle

Unraveling the Complexity of Lung Cancer Screening: Comparative Insights from Two Landmark Trials

By MedXY 09/14/2025

Lung cancer screening reduces mortality but varies by risk factors, sex, and cancer histology. Analysis of NELSON and NLST trials highlights histology-driven heterogeneity and suggests broader screening criteria may improve outcomes.

Clinical Updates Wellness & Lifestyle

Evaluating Diagnocat AI: Accuracy in Detecting Periapical Radiolucencies on CBCT Scans of Molars

By MedXY 09/14/2025

A study assessing the AI-based platform Diagnocat reveals high sensitivity but moderate specificity in detecting periapical radiolucencies on CBCT scans of non-root-filled molars, with decreased accuracy post-root treatment, underscoring the need for clinician oversight.

Clinical Updates Wellness & Lifestyle

Harnessing AI in Surgical Education: Deep Language Learning Model-Based Simulation Enhances Undergraduate History-Taking Skills

By MedXY 09/14/2025

A randomized controlled trial demonstrates that integrating deep language learning model (DLM) simulations into surgical training significantly improves history-taking skills and communication confidence among senior medical students.

Clinical Updates Wellness & Lifestyle

Enhancing Dental Diagnostics: The Role of AI Assistance in Detecting Periapical Radiolucencies

By MedXY 09/14/2025

A randomized controlled trial demonstrates that AI assistance moderately improves dentists' accuracy in diagnosing periapical radiolucencies, mainly by reducing false positives, with significant benefits for junior clinicians and a shift towards conservative treatment decisions.

Clinical Updates Wellness & Lifestyle

Enhancing Surgical History-Taking Skills in Medical Students Using AI-Driven Simulated Patients: A Randomized Controlled Trial

By MedXY 09/14/2025

This randomized trial shows that using a deep language learning model as a simulated patient significantly improves surgical history-taking skills and student confidence in senior medical students during clinical rotations.

Enhanced Therapeutic Outcomes in Overweight/Obese Women with PCOS: Combining Metformin and Semaglutide

Phase Ib Trial of Metformin Combined with Nivolumab in Refractory Solid Tumors: Safety, Dosage, and Preliminary Efficacy

Oral Metformin in Non-Muscle-Invasive Bladder Cancer: Insights from a Phase II Marker Lesion Study

Optimizing Anesthesia in Elderly NSCLC Patients: Impact of Midazolam and Dexmedetomidine Co-Administration on Hemodynamics and Stress Response

Why Do Chimpanzees Rarely Get Cancer? Unveiling a Key Evolutionary Difference That Could Revolutionize Immunotherapy

How Micronutrients Have Shaped Human DNA: Insights from Global Genetic Adaptations

Sudden Death Is Not So Sudden: Understanding, Preventing, and Responding to Cardiac Arrest

The Ginger Miracle? Exploring the Anti-Aging Potential of Ginger and What the Science Really Says

Citrate: The New Molecular Key to Reversing Vascular Aging and Combating Cardiovascular Disease

Enhanced Gait Rehabilitation in Chronic Stroke: Combining High-Intensity Interval Training with Robot-Assisted Gait Therapy

Enhanced Adenoma Detection in Water Exchange Colonoscopy Using AI: Insights from a Two-Center Randomized Trial

Advancing Clinical Care with AI Agents: Systematic Review of Performance and Integration in Medicine

Do Active People Really Live Longer? Twin Study Reveals the Complex Truth About Exercise, Aging, and Longevity

Evaluating AI-Enhanced EMG Reporting: Insights from a Randomized Controlled Trial

Harnessing AI for Personalized Depression Treatment: Insights from the AID-ME Cluster Randomized Trial

Unraveling the Complexity of Lung Cancer Screening: Comparative Insights from Two Landmark Trials

Evaluating Diagnocat AI: Accuracy in Detecting Periapical Radiolucencies on CBCT Scans of Molars

Harnessing AI in Surgical Education: Deep Language Learning Model-Based Simulation Enhances Undergraduate History-Taking Skills

Enhancing Dental Diagnostics: The Role of AI Assistance in Detecting Periapical Radiolucencies

Enhancing Surgical History-Taking Skills in Medical Students Using AI-Driven Simulated Patients: A Randomized Controlled Trial

Immunogenicity and Safety of the VLA15 Lyme Borreliosis Vaccine Across Age Groups: A Phase 2 Randomised Controlled Trial and Integrative Review

MACRO Trial Insights: Endoscopic Sinus Surgery Outperforms Clarithromycin in Chronic Rhinosinusitis Management

Adjunctive Corticosteroids in Severe Pneumocystis jirovecii Pneumonia Among HIV-negative Patients: Insights from a Multicentre Randomised Trial

Evaluating BDLC Regimen in Pre-XDR Tuberculosis: Findings from the endTB-Q Phase 3 Trial