Medxy AI – Page 55

Long-Term Exposure to Air and Road Traffic Noise Pollution Increases Risk of Valvular Heart Disease: Insights from a UK Biobank Prospective Study

By MedXY 10/23/2025

This review synthesizes recent evidence linking long-term air and noise pollution exposure with increased incidence of valvular heart disease, highlighting findings from a large UK Biobank cohort study, underlying mechanisms, and clinical implications.

Clinical Updates Psychiatry Public Health

Long-Term Exposure to Air Pollution and Road Traffic Noise: Associations with Antidepressant Medication Dispensing in Swedish Adults

By MedXY 10/23/2025

This review synthesizes evidence linking long-term air pollution and road traffic noise exposure with antidepressant medication dispensing, highlighting sex-specific associations and implications for mental health prevention strategies.

Psychiatry Public Health Specialties

Long-Term PM2.5 Exposure and Mental Health Disparities: Insights from the All of Us Research Program

By MedXY 10/22/2025

This prospective study reveals that prolonged exposure to fine particulate matter (PM2.5) significantly elevates risks of depression and anxiety, disproportionately affecting Black populations due to systemic inequities. Findings call for targeted environmental and public health interventions.

Psychiatry Specialties

Reducing Suicide Risk in Bipolar Disorder: The Impact of Lithium, Valproate, and Atypical Antipsychotics in Long-Term Treatment

By MedXY 10/22/2025

This study reveals that long-term treatment with lithium or valproate significantly lowers suicide risks in bipolar disorder patients. Combining atypical antipsychotics with these mood stabilizers further reduces suicide incidence, offering critical insights for managing high-risk individuals.

news Oncology

Enhancing Fertility Preservation and Ovarian Function in Young Women with Breast Cancer: Insights from International Prospective Studies

By MedXY 10/22/2025

This article reviews a joint analysis of the Joven & Fuerte and PREFER studies, highlighting disparities in fertility preservation strategies among Mexican and Italian young women with breast cancer, and discusses implications for clinical practice.

Diabetes & Endocrinology OB/GYN & Women's Health Specialties

Navigating the Frontiers of Premature Ovarian Insufficiency Research: Insights from the Top 100 Influential Articles

By MedXY 10/22/2025

A comprehensive bibliometric analysis of the 100 most-cited articles in premature ovarian insufficiency reveals key research trends, leading contributors, and emerging scientific directions in genetics, cardiovascular disease, and immunology.

Diabetes & Endocrinology HIV/AIDS Internal Medicine Specialties

Nucleoside Reverse Transcriptase Inhibitors: A Novel Therapeutic Avenue Against Inflammaging and Age-Related Diseases

By MedXY 10/22/2025

NRTIs, traditionally used in HIV and HBV treatment, demonstrate promising anti-inflammatory effects that may reduce the incidence of age-related diseases by inhibiting inflammaging processes associated with endogenous retroelements.

HIV/AIDS Infectious Diseases news

Accelerated Epigenetic Aging in HIV: Insights from a Systematic Review

By MedXY 10/22/2025

Systematic review evidence supports accelerated epigenetic aging in people living with HIV compared to uninfected individuals, highlighting the need for further research considering antiretroviral therapy and confounding factors.

Infectious Diseases Public Health Specialties

Tomatine: A Novel Natural Adjuvant Enhancing mRNA Vaccine Efficacy in Cancer and Infectious Diseases

By MedXY 10/22/2025

Tomatine, a natural compound incorporated into mRNA vaccine nanocarriers, significantly enhances antigen expression and innate immune activation, boosting adaptive immunity against tumors and SARS-CoV-2, underscoring its potential as a versatile vaccine adjuvant.

Infectious Diseases news Public Health

Decoding Multidrug-Resistant Tuberculosis in Hainan Island: Linking Genotypes to Resistance Levels for Optimized Treatment

By MedXY 10/22/2025

This study elucidates drug resistance patterns and genotype-phenotype correlations in multidrug-resistant Mycobacterium tuberculosis strains from Hainan Island, China, revealing implications for tailored MIC-based therapies.

news

解码海南岛耐多药结核病：基因型与耐药水平关联以优化治疗

By MedXY 10/22/2025

本研究阐明了来自中国海南岛的耐多药结核分枝杆菌株的耐药模式和基因型-表型相关性，揭示了基于最小抑菌浓度（MIC）的个体化治疗策略的潜在意义。

Infectious Diseases news Respiratory

Unraveling Mixed Infections and Heteroresistance in Multidrug-Resistant Tuberculosis: Insights from a Genomic Study in Shanghai

By MedXY 10/22/2025

A genomic epidemiological study reveals that mixed infections and heteroresistance are prevalent among multidrug-resistant tuberculosis cases in Shanghai, complicating diagnosis and treatment.

HIV/AIDS Infectious Diseases Specialties

Long-Term Health Risks in HIV Patients with Immune Non-Response Despite Antiretroviral Therapy

By MedXY 10/22/2025

Immune non-response despite ART in people with HIV significantly increases risk of both AIDS-defining and non-AIDS-defining comorbidities, underscoring the need for enhanced risk assessment beyond CD4+ T-cell counts.

Dermatology HIV/AIDS Specialties

Evolving Dermatologic Landscape in HIV: Prevalence, Incidence, and Risk Factors in the Modern ART Era from the DC Cohort

By MedXY 10/22/2025

Despite advances in antiretroviral therapy, dermatologic diseases remain prevalent in people with HIV, with incidence declining yet significant disparities persisting related to immune status, demographics, and structural factors.

Neurology news

ESCAPE-NEXT Trial: Nerinetide Fails to Improve Functional Outcomes in Acute Ischaemic Stroke Patients Undergoing Endovascular Thrombectomy Without Prior Thrombolysis

By MedXY 10/22/2025

The ESCAPE-NEXT trial evaluated nerinetide for acute ischaemic stroke patients undergoing thrombectomy without prior thrombolysis. Nerinetide showed no significant improvement in functional outcomes or safety concerns, highlighting the need for further research into optimal patient selection and treatment timing.

Ophthalmology Specialties

Intravenous Alteplase Versus Oral Aspirin in Acute Central Retinal Artery Occlusion: Insights from the THEIA Phase 3 Trial and Contextual Evidence

By MedXY 10/22/2025

THEIA trial evaluated intravenous alteplase against oral aspirin in acute CRAO within 4.5 hours; no significant visual improvement difference was found, emphasizing the need for further research and meta-analyses to clarify thrombolysis benefits.

Cardiology Neurology Specialties

Long-Term Stroke Risk in Healthy Women: The Predictive Role of hsCRP, LDL Cholesterol, and Lipoprotein(a)

By MedXY 10/22/2025

A 30-year prospective study reveals that elevated hsCRP, LDL cholesterol, and lipoprotein(a) levels independently and collectively increase the risk of ischaemic stroke in healthy women, advocating for early biomarker screening in stroke prevention.

news

健康女性の長期脳卒中リスク：hsCRP、LDLコレステロール、リポタンパク質(a)の予測役割

By MedXY 10/22/2025

30年間の前向き研究では、hsCRP、LDLコレステロール、リポタンパク質(a)の上昇が、健康な女性の虚血性脳卒中のリスクを独立してかつ共同で増加させることを明らかにしました。この結果は、脳卒中予防における早期バイオマーカー検査の重要性を示しています。

Infectious Diseases Public Health Specialties

Unmasking the Silent Spread: Screening Asymptomatic Tuberculosis in Household Contacts in South Africa

By MedXY 10/22/2025

This study reveals that over 80% of tuberculosis cases among South African household contacts are asymptomatic and often missed by symptom and chest X-ray screening, highlighting the need for improved diagnostic strategies to detect subclinical TB.

Infectious Diseases news Pediatrics

Outpatient Versus Inpatient Care for Young Infants with Single Low-Risk PSBI Signs: Insights from a Multicentre Trial in Sub-Saharan Africa and South Asia

By MedXY 10/22/2025

A randomized trial found outpatient treatment of young infants with a single low-mortality-risk sign of possible serious bacterial infection is non-inferior to inpatient care, with lower mortality rates and comparable safety.

Long-Term Exposure to Air and Road Traffic Noise Pollution Increases Risk of Valvular Heart Disease: Insights from a UK Biobank Prospective Study

Long-Term Exposure to Air Pollution and Road Traffic Noise: Associations with Antidepressant Medication Dispensing in Swedish Adults

Long-Term PM2.5 Exposure and Mental Health Disparities: Insights from the All of Us Research Program

Reducing Suicide Risk in Bipolar Disorder: The Impact of Lithium, Valproate, and Atypical Antipsychotics in Long-Term Treatment

Enhancing Fertility Preservation and Ovarian Function in Young Women with Breast Cancer: Insights from International Prospective Studies

Navigating the Frontiers of Premature Ovarian Insufficiency Research: Insights from the Top 100 Influential Articles

Accelerated Epigenetic Aging in HIV: Insights from a Systematic Review

Tomatine: A Novel Natural Adjuvant Enhancing mRNA Vaccine Efficacy in Cancer and Infectious Diseases

Decoding Multidrug-Resistant Tuberculosis in Hainan Island: Linking Genotypes to Resistance Levels for Optimized Treatment

解码海南岛耐多药结核病：基因型与耐药水平关联以优化治疗

Unraveling Mixed Infections and Heteroresistance in Multidrug-Resistant Tuberculosis: Insights from a Genomic Study in Shanghai

Long-Term Health Risks in HIV Patients with Immune Non-Response Despite Antiretroviral Therapy

Evolving Dermatologic Landscape in HIV: Prevalence, Incidence, and Risk Factors in the Modern ART Era from the DC Cohort

ESCAPE-NEXT Trial: Nerinetide Fails to Improve Functional Outcomes in Acute Ischaemic Stroke Patients Undergoing Endovascular Thrombectomy Without Prior Thrombolysis

Intravenous Alteplase Versus Oral Aspirin in Acute Central Retinal Artery Occlusion: Insights from the THEIA Phase 3 Trial and Contextual Evidence

Long-Term Stroke Risk in Healthy Women: The Predictive Role of hsCRP, LDL Cholesterol, and Lipoprotein(a)

健康女性の長期脳卒中リスク：hsCRP、LDLコレステロール、リポタンパク質(a)の予測役割

Unmasking the Silent Spread: Screening Asymptomatic Tuberculosis in Household Contacts in South Africa

Outpatient Versus Inpatient Care for Young Infants with Single Low-Risk PSBI Signs: Insights from a Multicentre Trial in Sub-Saharan Africa and South Asia

Why Our Strength and Fitness Peak in Our 20s–30s — and How Exercise Can Push Back the Clock

Heart Failure Mortality: The Resilient Challenge in an Era of Declining Cardiovascular Deaths

Moving Beyond Injectables: SOR102 Shows Promise as an Oral Dual-Inhibitor for Ulcerative Colitis

Transdiagnostic Prediction Model Accurately Identifies Risk for Psychotic and Bipolar Disorders in Clinical Practice