Medxy AI

Equally Effective Dual Therapy Combinations for Hypertension in Indian Patients: Insights from a Landmark Randomized Trial

By MedXY 09/19/2025

This multicenter randomized trial in India shows that three dual antihypertensive combinations—amlodipine-perindopril, perindopril-indapamide, and amlodipine-indapamide—are equally effective and well-tolerated for 24-hour blood pressure control in South Asian adults.

Clinical Updates Wellness & Lifestyle

Amiloride vs Spironolactone for Resistant Hypertension: A New Alternative Backed by Randomized Trial Evidence

By MedXY 09/19/2025

A recent randomized clinical trial demonstrates amiloride's noninferiority to spironolactone in lowering systolic blood pressure in resistant hypertension, offering a promising alternative therapy.

Clinical Updates Wellness & Lifestyle

Opt-Out vs Opt-In Behavioral Framing in Remote Blood Pressure Monitoring: Insights from a Pragmatic Randomized Clinical Trial

By MedXY 09/19/2025

A randomized clinical trial evaluating behavioral economic framing for remote blood pressure monitoring found no significant difference in patient enrollment or retention between opt-out and opt-in approaches, though both improved blood pressure control compared to usual care.

Clinical Updates Wellness & Lifestyle

Enhancing Hospitalist Care of Undifferentiated Dyspnea with Cardiopulmonary Point-of-Care Ultrasonography: Reducing Length of Stay and Costs

By MedXY 09/19/2025

Implementation of cardiopulmonary POCUS in hospitalist management of undifferentiated dyspnea significantly reduces hospital length of stay and costs, though adoption remains limited, highlighting the need for sustained training and support.

Clinical Updates Wellness & Lifestyle

Evaluating the Long-Term Effects of Cocoa Extract Supplementation on the Development of Hypertension: Insights from the COSMOS Trial

By MedXY 09/19/2025

The large-scale COSMOS trial reveals that while long-term cocoa extract supplementation does not reduce overall incident hypertension in older adults, it significantly lowers risk among individuals with normal baseline systolic blood pressure.

Clinical Updates Wellness & Lifestyle

Henagliflozin and Aging Biomarkers in Type 2 Diabetes: A Groundbreaking Multicenter Trial Reveals Promising Anti-Aging Effects

By MedXY 09/18/2025

A randomized placebo-controlled trial demonstrates that henagliflozin improves telomere length and multiple aging biomarkers in patients with type 2 diabetes, suggesting potential anti-aging benefits beyond glucose control.

Clinical Updates Wellness & Lifestyle

Advancing Care in Older Adult T-Cell Leukemia/Lymphoma: Phase 2 Trial of Moga-CHOP-14 Combination Therapy

By MedXY 09/18/2025

A phase 2 study demonstrated that combining mogamulizumab with CHOP chemotherapy improves progression-free survival in older patients with adult T-cell leukemia/lymphoma, highlighting a promising first-line option.

Clinical Updates Wellness & Lifestyle

Fulmetibant’s Role in Diabetic Neuropathic Pain: Insights from the Phase 2a BRADiNP Study

By MedXY 09/18/2025

The BRADiNP study found that fulmetibant, a bradykinin-1 receptor antagonist, failed to significantly reduce diabetic neuropathic pain compared to placebo, despite favorable safety profiles, highlighting challenges in translating preclinical success to clinical efficacy.

Clinical Updates Wellness & Lifestyle

Lobeglitazone as an Effective and Safe Addition to Metformin and Sitagliptin Therapy in Type 2 Diabetes: Results from a 52-Week Multicentre Phase III Trial

By MedXY 09/18/2025

This phase III trial showed that adding lobeglitazone to metformin and sitagliptin significantly improves glycaemic control and insulin sensitivity with favorable safety over 52 weeks in Korean patients with type 2 diabetes inadequately controlled by dual therapy.

Wellness & Lifestyle

Why Losing Weight Can Worsen Fatty Liver Disease: The Crucial Role of Balanced Nutrition

By MedXY 09/18/2025

Losing weight doesn't always mean improving fatty liver disease. Discover why strict diets lacking essential proteins can worsen liver health and learn practical dietary strategies to manage and reverse fatty liver effectively.

Wellness & Lifestyle

Nourishing Your Thyroid: How Common Vegetables Support Thyroid Health Through Selenium and More

By MedXY 09/18/2025

Thyroid health depends on balanced nutrition, including selenium from everyday vegetables like tomatoes. Discover six key vegetables that support thyroid function and debunk myths about diet and thyroid disease.

Clinical Updates Wellness & Lifestyle

Repurposing Antihypertensive Drug Trazosin to Delay Vascular Aging: A Breakthrough in Atherosclerosis Management

By MedXY 09/18/2025

New research identifies transcription factor ATF3 as a key regulator of vascular smooth muscle cell aging and reveals low-dose trazosin, a commonly used antihypertensive, as a potential therapy to delay vascular aging and atherosclerosis progression via autophagy enhancement.

Wellness & Lifestyle

From Plate to Progress: Five Scientifically Proven Diets to Help Manage Obesity Effectively

By MedXY 09/18/2025

Explore five scientifically supported dietary patterns that aid effective weight loss for individuals struggling with obesity, emphasizing balanced nutrition and sustainable lifestyle changes.

Medical News Wellness & Lifestyle

Navigating the 2025 Best Diets: Tailored Eating Plans for Weight Loss, Hypertension, Menopause, and More

By MedXY 09/18/2025

The 2025 Best Diets ranking identifies optimal eating plans tailored to specific health needs, such as weight loss, high blood pressure, menopause, and digestive health, emphasizing scientifically backed, sustainable dietary patterns.

Wellness & Lifestyle

Unlocking the Secrets of the Best Diets: A 2025 Guide to Health, Weight Control, and Brain Protection

By MedXY 09/18/2025

Explore the 2025 top diet rankings highlighting Mediterranean, DASH, Flexible Vegetarian, and Brain-boosting diets, tailored for controlling blood pressure, aiding weight loss, and preventing dementia.

Medical News Wellness & Lifestyle

Does Drinking More Than 3.5 Cups of Milk Weekly Raise Liver Cancer Risk? Unpacking the Facts Behind the Rumor

By MedXY 09/18/2025

A recent Harvard study linking high milk consumption to increased liver cancer risk has sparked confusion. This article clarifies the scientific evidence, dispels misconceptions, and offers guidance on healthy milk consumption based on current research and dietary guidelines.

Medical News Wellness & Lifestyle

Coenzyme Q10: A Natural Ally Against Ovarian Aging and a Booster for Female Fertility

By MedXY 09/18/2025

Scientific evidence highlights coenzyme Q10 supplementation as a promising intervention to combat ovarian aging, improve oocyte quality, and enhance female fertility, especially for women over 35 or with compromised ovarian reserve.

Clinical Updates Wellness & Lifestyle

Neutrophil Counts and Type 2 Diabetes Remission: Long-Term Benefits of Mediterranean Diet in Coronary Heart Disease Patients from the CORDIOPREV Study

By MedXY 09/18/2025

Lower neutrophil counts predict greater type 2 diabetes remission with a Mediterranean diet in coronary heart disease patients, highlighting immune involvement in metabolic improvement over 5 years.

Wellness & Lifestyle

Why Do Kids Grind Their Teeth at Night? Understanding Pediatric Bruxism

By MedXY 09/18/2025

Children's nighttime teeth grinding, or bruxism, is common and often caused by various physiological, dental, health, emotional, genetic, and behavioral factors. This article explores its causes, misconceptions, clinical implications, and management strategies.

Clinical Updates Wellness & Lifestyle

Impact of Mediterranean Diet and Physical Activity on Bone Health in Older Adults: Insights from the PREDIMED-Plus Trial

By MedXY 09/18/2025

A 3-year randomized trial reveals that a weight-loss Mediterranean diet combined with physical activity helps prevent bone mineral density decline in older women with metabolic syndrome.

Equally Effective Dual Therapy Combinations for Hypertension in Indian Patients: Insights from a Landmark Randomized Trial

Amiloride vs Spironolactone for Resistant Hypertension: A New Alternative Backed by Randomized Trial Evidence

Opt-Out vs Opt-In Behavioral Framing in Remote Blood Pressure Monitoring: Insights from a Pragmatic Randomized Clinical Trial

Enhancing Hospitalist Care of Undifferentiated Dyspnea with Cardiopulmonary Point-of-Care Ultrasonography: Reducing Length of Stay and Costs

Evaluating the Long-Term Effects of Cocoa Extract Supplementation on the Development of Hypertension: Insights from the COSMOS Trial

Henagliflozin and Aging Biomarkers in Type 2 Diabetes: A Groundbreaking Multicenter Trial Reveals Promising Anti-Aging Effects

Advancing Care in Older Adult T-Cell Leukemia/Lymphoma: Phase 2 Trial of Moga-CHOP-14 Combination Therapy

Fulmetibant’s Role in Diabetic Neuropathic Pain: Insights from the Phase 2a BRADiNP Study

Lobeglitazone as an Effective and Safe Addition to Metformin and Sitagliptin Therapy in Type 2 Diabetes: Results from a 52-Week Multicentre Phase III Trial

Why Losing Weight Can Worsen Fatty Liver Disease: The Crucial Role of Balanced Nutrition

Nourishing Your Thyroid: How Common Vegetables Support Thyroid Health Through Selenium and More

Repurposing Antihypertensive Drug Trazosin to Delay Vascular Aging: A Breakthrough in Atherosclerosis Management

From Plate to Progress: Five Scientifically Proven Diets to Help Manage Obesity Effectively

Navigating the 2025 Best Diets: Tailored Eating Plans for Weight Loss, Hypertension, Menopause, and More

Unlocking the Secrets of the Best Diets: A 2025 Guide to Health, Weight Control, and Brain Protection

Does Drinking More Than 3.5 Cups of Milk Weekly Raise Liver Cancer Risk? Unpacking the Facts Behind the Rumor

Coenzyme Q10: A Natural Ally Against Ovarian Aging and a Booster for Female Fertility

Neutrophil Counts and Type 2 Diabetes Remission: Long-Term Benefits of Mediterranean Diet in Coronary Heart Disease Patients from the CORDIOPREV Study

Why Do Kids Grind Their Teeth at Night? Understanding Pediatric Bruxism

Impact of Mediterranean Diet and Physical Activity on Bone Health in Older Adults: Insights from the PREDIMED-Plus Trial

Efficacy of Bictegravir-Based Regimen vs. Ritonavir-Boosted Protease Inhibitors in HIV Patients on Second-Line Therapy in Haiti: Insights from a Randomized Non-Inferiority Trial

Hiệu quả của phác đồ dựa trên Bictegravir so với các chất ức chế protease được tăng cường bằng Ritonavir ở bệnh nhân HIV đang điều trị tuyến thứ hai tại Haiti: Những hiểu biết từ một thử nghiệm không thua kém ngẫu nhiên

Four Fruits You Shouldn’t Skimp On This Summer: Nature’s Skin-Boosting Superfoods

The Double-Edged Sword of Curcumin: How Excessive Turmeric Supplements Can Harm Your Liver