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Decade-Long Insights into Deferred Versus Immediate Stenting in STEMI Patients: DANAMI-3-DEFER Trial Findings
Posted inCardiology Specialties

Decade-Long Insights into Deferred Versus Immediate Stenting in STEMI Patients: DANAMI-3-DEFER Trial Findings

Posted by MedXY By MedXY 08/17/2025
The 10-year DANAMI-3-DEFER study compared deferred stenting to immediate stenting in STEMI, showing no mortality benefit but reduced heart failure hospitalizations with deferred stenting.
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Early TAVR Benefits in Asymptomatic Severe Aortic Stenosis: Insights from Cardiac Biomarker Analysis in the EARLY TAVR Trial
Posted inCardiology news Specialties

Early TAVR Benefits in Asymptomatic Severe Aortic Stenosis: Insights from Cardiac Biomarker Analysis in the EARLY TAVR Trial

Posted by MedXY By MedXY 08/17/2025
Cardiac biomarkers NT-proBNP and hs-cTnT predict higher risk in asymptomatic severe aortic stenosis, but early TAVR benefits patients regardless of biomarker levels, with greater relative advantage seen in those with lower biomarker concentrations.
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Oral Semaglutide in Type 2 Diabetes: Efficacy and Safety with and without SGLT2 Inhibitors from the SOUL Trial
Posted inCardiology Diabetes & Endocrinology news Specialties

Oral Semaglutide in Type 2 Diabetes: Efficacy and Safety with and without SGLT2 Inhibitors from the SOUL Trial

Posted by MedXY By MedXY 08/17/2025
The SOUL trial demonstrates that oral semaglutide significantly reduces major cardiovascular events in type 2 diabetes patients, independently of concurrent SGLT2 inhibitor use, with a favorable safety profile.
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Advancements in Transcatheter Edge-to-Edge Repair for Severe Tricuspid Regurgitation: Insights from the TRILUMINATE Pivotal Trial
Posted inCardiology Specialties

Advancements in Transcatheter Edge-to-Edge Repair for Severe Tricuspid Regurgitation: Insights from the TRILUMINATE Pivotal Trial

Posted by MedXY By MedXY 08/17/2025
Transcatheter edge-to-edge repair (TEER) offers a safe, effective option to reduce tricuspid regurgitation severity, improve quality of life, and lower heart failure hospitalizations up to two years, including in patients with cardiac implantable electronic device leads.
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Inclisiran Shows Promise for Adolescents with Homozygous Familial Hypercholesterolemia: Results from the ORION-13 Trial
Posted inCardiology Specialties

Inclisiran Shows Promise for Adolescents with Homozygous Familial Hypercholesterolemia: Results from the ORION-13 Trial

Posted by MedXY By MedXY 08/17/2025
The ORION-13 trial demonstrates that inclisiran significantly lowers LDL cholesterol by 33.3% and is safe and well tolerated in adolescents with homozygous familial hypercholesterolemia, addressing an unmet pediatric treatment need.
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Renal Denervation Shows Sustained Blood Pressure Reduction and Safety Over 24 Months in SPYRAL HTN-ON MED Trial
Posted inCardiology Clinical Updates General Surgery news Specialties

Renal Denervation Shows Sustained Blood Pressure Reduction and Safety Over 24 Months in SPYRAL HTN-ON MED Trial

Posted by MedXY By MedXY 08/17/2025
The SPYRAL HTN-ON MED trial demonstrates that renal denervation provides significant long-term reductions in both ambulatory and office systolic blood pressure with good safety, supporting its role in managing hypertension.
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Higher Risk of Major Gastrointestinal Bleeding with Edoxaban vs Warfarin After TAVR: Insights from the ENVISAGE-TAVI AF Trial
Posted inCardiology news Specialties

Higher Risk of Major Gastrointestinal Bleeding with Edoxaban vs Warfarin After TAVR: Insights from the ENVISAGE-TAVI AF Trial

Posted by MedXY By MedXY 08/17/2025
The ENVISAGE-TAVI AF trial found that patients with atrial fibrillation undergoing TAVR had a higher incidence of major gastrointestinal bleeding when treated with edoxaban compared to warfarin, highlighting the importance of risk factor identification.
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Edoxaban as a Safe and Effective Anticoagulant Early After Bioprosthetic Valve Replacement: Insights from the ENBALV Trial
Posted inCardiology Specialties

Edoxaban as a Safe and Effective Anticoagulant Early After Bioprosthetic Valve Replacement: Insights from the ENBALV Trial

Posted by MedXY By MedXY 08/17/2025
The ENBALV randomized trial demonstrates that edoxaban offers a potential safe and efficacious alternative to warfarin for anticoagulation within three months after surgical bioprosthetic valve replacement, with comparable thromboembolic event rates and a distinct safety profile.
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ADVANTAGE AF Phase 2: Evaluating Pulsed Field Ablation for Persistent Atrial Fibrillation Using Continuous ECG Monitoring
Posted inCardiology news Specialties

ADVANTAGE AF Phase 2: Evaluating Pulsed Field Ablation for Persistent Atrial Fibrillation Using Continuous ECG Monitoring

Posted by MedXY By MedXY 08/17/2025
The ADVANTAGE AF Phase 2 study demonstrates pulsed field ablation's safety and efficacy for persistent atrial fibrillation, introducing continuous cardiac monitoring to better assess arrhythmia burden and outcomes over one year.
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Long-Term Safety of Subcutaneous vs. Transvenous ICDs: Results from the PRAETORIAN-XL Trial
Posted inCardiology Specialties

Long-Term Safety of Subcutaneous vs. Transvenous ICDs: Results from the PRAETORIAN-XL Trial

Posted by MedXY By MedXY 08/17/2025
The PRAETORIAN-XL trial shows subcutaneous ICDs have fewer major and lead-related complications than transvenous ICDs over 8 years, suggesting S-ICD as a safer option for patients without pacing needs.
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Optimizing Sedation for Pulsed-Field Ablation in Atrial Fibrillation: Results of the COOPERATIVE-PFA Trial
Posted inCardiology news Specialties

Optimizing Sedation for Pulsed-Field Ablation in Atrial Fibrillation: Results of the COOPERATIVE-PFA Trial

Posted by MedXY By MedXY 08/17/2025
This randomized trial compares sedation regimens for pulsed-field ablation in atrial fibrillation, finding remimazolam-ketamine deep analgosedation superior to propofol-opioid approaches in reducing hypoxemia and hypotension.
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High-Dose Statins and Their Impact on the Progression of Small Abdominal Aortic Aneurysms: Insights from a 5-Year Danish Cohort Study
Posted inCardiology Clinical Updates news Specialties

High-Dose Statins and Their Impact on the Progression of Small Abdominal Aortic Aneurysms: Insights from a 5-Year Danish Cohort Study

Posted by MedXY By MedXY 08/17/2025
This 5-year prospective cohort study reveals that high-dose statin therapy significantly slows abdominal aortic aneurysm growth and reduces the risks of repair, rupture, and death in men, suggesting benefits beyond traditional cardiovascular risk management.
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Unraveling the Link Between Somatic JAK2V617F Mutation and Ascending Aortic Aneurysms: Evidence from a Large-Scale Cardiovascular Screening
Posted innews Rheumatology Specialties

Unraveling the Link Between Somatic JAK2V617F Mutation and Ascending Aortic Aneurysms: Evidence from a Large-Scale Cardiovascular Screening

Posted by MedXY By MedXY 08/17/2025
A multicenter Danish study reveals a strong independent association between somatic JAK2V617F mutation—especially its variant allele frequency—and risk of ascending aortic aneurysms, suggesting targeted screening strategies.
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Evaluating Electronic Nudges to Enhance Guideline-Directed Therapy in Chronic Kidney Disease: Insights from the NUDGE-CKD Trial
Posted inAI Clinical Updates Nephrology news Specialties

Evaluating Electronic Nudges to Enhance Guideline-Directed Therapy in Chronic Kidney Disease: Insights from the NUDGE-CKD Trial

Posted by MedXY By MedXY 08/16/2025
The NUDGE-CKD trial found that electronic letter-based nudges to patients with chronic kidney disease and their general practitioners did not significantly improve initiation of guideline-recommended medications over usual care.
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Abelacimab vs. Rivaroxaban in Atrial Fibrillation Patients on Antiplatelet Therapy: Insights from the AZALEA-TIMI 71 Trial
Posted inCardiology Clinical Updates news Specialties

Abelacimab vs. Rivaroxaban in Atrial Fibrillation Patients on Antiplatelet Therapy: Insights from the AZALEA-TIMI 71 Trial

Posted by MedXY By MedXY 08/16/2025
The AZALEA-TIMI 71 trial shows abelacimab, a novel factor XI inhibitor, reduces bleeding risk compared to rivaroxaban in atrial fibrillation patients on antiplatelet therapy, suggesting a safer anticoagulation alternative.
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High-Risk Plaques in Non-Culprit Lesions: Comparative Outcomes After NSTEMI and STEMI
Posted inCardiology Clinical Updates news Specialties

High-Risk Plaques in Non-Culprit Lesions: Comparative Outcomes After NSTEMI and STEMI

Posted by MedXY By MedXY 08/16/2025
This study examines the morphology of high-risk plaques in non-culprit coronary lesions among NSTEMI and STEMI patients and their impact on clinical outcomes, suggesting comparable prevalence of high-risk features but differing plaque characteristics between these groups.
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Enhancing Cardiovascular Risk Prediction and Outcomes with Coronary CT Angiography: Insights from the PROMISE and SCOT-HEART Trials
Posted inCardiology news Specialties

Enhancing Cardiovascular Risk Prediction and Outcomes with Coronary CT Angiography: Insights from the PROMISE and SCOT-HEART Trials

Posted by MedXY By MedXY 08/16/2025
Coronary CTA, guided by clinical risk models and advanced radiomic plaque analysis, improves prediction and prevention of myocardial infarction in patients with new-onset chest pain, particularly in those with low clinical likelihood of coronary artery disease.
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Semaglutide’s Impact on Cardiovascular Outcomes Across Chronic Kidney Disease Stages in Type 2 Diabetes: Insights from the FLOW Trial
Posted inCardiology Diabetes & Endocrinology Nephrology Specialties

Semaglutide’s Impact on Cardiovascular Outcomes Across Chronic Kidney Disease Stages in Type 2 Diabetes: Insights from the FLOW Trial

Posted by MedXY By MedXY 08/16/2025
The FLOW trial demonstrates that semaglutide significantly lowers cardiovascular risks and mortality in type 2 diabetes patients with chronic kidney disease, independently of CKD severity.
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Revolutionizing Acute Myocardial Infarction Diagnosis: Insights from a New Clinical Classification Using Cardiac Imaging
Posted inCardiology Clinical Updates news Radiology Specialties

Revolutionizing Acute Myocardial Infarction Diagnosis: Insights from a New Clinical Classification Using Cardiac Imaging

Posted by MedXY By MedXY 08/16/2025
A novel clinical classification incorporating cardiac imaging refines diagnosis of acute myocardial infarction, distinguishing spontaneous, secondary, and non-infarction cases, improving risk stratification and guiding targeted treatment.
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Pregnancies Following Peri-Partum Cardiomyopathy: Insights from the ESC EuroObservational Research Programme
Posted inCardiology OB/GYN & Women's Health Specialties

Pregnancies Following Peri-Partum Cardiomyopathy: Insights from the ESC EuroObservational Research Programme

Posted by MedXY By MedXY 08/16/2025
This study analyses maternal and neonatal outcomes in subsequent pregnancies after peri-partum cardiomyopathy (PPCM), revealing lower than expected maternal risks and suggesting potential reclassification of pregnancy risk categories based on ventricular function.
Read More

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  • Safety First: Concurrent Metastases-Directed Stereotactic Radiotherapy and Biological Therapy Show Low Risk of Severe Adverse Events
  • Environmental Cardiotoxicity: PM2.5 and Ozone Exposure Double the Risk of Cardiac Dysfunction in Breast Cancer Patients
  • Docetaxel Rechallenge vs Cabazitaxel: Choosing the Right Taxane Sequence in Metastatic Castration-Resistant Prostate Cancer
  • Moving Beyond Birthdays: Five-Year Absolute Risk-Based Screening Outperforms Age-Based Mammography
  • Beyond the Count: How Product Factors and High Thresholds Shape Pediatric Platelet Transfusion Outcomes
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