Medxy AI – Page 111

Unraveling the Link Between General Intelligence and Alcohol Use Disorder Risk

By MedXY 10/01/2025

This article reviews emerging evidence on how general intelligence and cognitive performance relate to the risk of alcohol use disorder, integrating large-scale population data, genetic analyses, and the role of educational attainment across national contexts.

Clinical Updates Oncology Specialties

Deciphering the Role of Intratumoral Microbiota in Breast Cancer: Pathogenesis to Precision Therapeutics

By MedXY 09/30/2025

Intratumoral microbiota significantly influence breast cancer development, progression, and therapeutic response. Their diverse composition across subtypes presents diagnostic and prognostic opportunities. Emerging strategies target these microbes to improve treatment efficacy and overcome resistance.

Clinical Updates Oncology

Novel Heparanase Inhibitor LMW-DSS Shows Promise in Preventing Breast Cancer Metastasis by Targeting Migration and Angiogenesis

By MedXY 09/30/2025

Low-molecular-weight dextran sulfate sodium (LMW-DSS), a new heparanase inhibitor, effectively prevents breast cancer metastasis in mice by inhibiting cancer cell migration and angiogenesis, offering a promising therapeutic approach with minimal bleeding risk.

Clinical Updates Oncology Specialties

Advancing Immunotherapy in Head and Neck Cancer: A Curcumin-Based Polymer Prodrug Nanoplatform Targeting Cancer Stemness and Tumor Microenvironment

By MedXY 09/29/2025

A novel curcumin-based polymer prodrug nanoplatform enhances immunotherapy in head and neck cancer by targeting tumor cell stemness and reversing immunosuppression via synergistic photothermal, photodynamic, and ferroptosis mechanisms.

Neurology Pediatrics Psychiatry Specialties

Unraveling ADHD: Gut Microbial Signatures and the Role of SCFA Deficiency in Symptom Pathogenesis

By MedXY 09/29/2025

Recent research reveals distinct gut microbial and metabolic profiles linked to ADHD symptoms, highlighting short-chain fatty acid deficiency as a key mechanism driving hyperactivity and inattention.

Clinical Updates Neurology Specialties

Early-Life Gut Microbiome Maturity: A Key Regulator of Blood-Brain Barrier Integrity and Cognitive Development

By MedXY 09/29/2025

This study demonstrates that the maturity of the early-life gut microbiome influences blood-brain barrier integrity and cognitive functions, highlighting a novel therapeutic target for neurodevelopmental disorders.

Medical News Pediatrics Psychiatry Specialties

Restoring Cognitive Function After Adolescent Alcohol Exposure: The Promise of Synbiotic Therapy Targeting the Microbiota-Gut-Brain Axis

By MedXY 09/29/2025

A synbiotic intervention reverses alcohol-induced cognitive deficits in adolescent mice by modulating gut microbiota and brain metabolism, suggesting potential therapeutic avenues for alcohol-related neurobehavioral impairments.

Clinical Updates Neurology Specialties

NLRP3 Inflammasome and Gut Microbiota-Brain Axis: Emerging Insights into White Matter Injury After Intracerebral Hemorrhage

By MedXY 09/29/2025

This article explores how gut microbiota dysbiosis and NLRP3 inflammasome activation contribute to secondary white matter injury post-intracerebral hemorrhage, outlining mechanisms and potential therapeutic strategies.

Diabetes & Endocrinology Family Medicine & Nutrition news Specialties

Preserving Bone Quality in Older Adults with Obesity Through Lifestyle Intervention: Insights from the LIMB-Q Trial

By MedXY 09/29/2025

The LIMB-Q trial demonstrates that intensive lifestyle interventions combining weight management and exercise preserve bone quality in older adults with obesity, despite significant weight loss, highlighting a promising approach for mitigating osteoporosis risk during aging.

Allergy & Immunology Medical News news Pediatrics Public Health Specialties

In-Home Firearm Homicides Among Children and Adolescents: Understanding a Hidden Crisis

By MedXY 09/29/2025

Nearly one-quarter of firearm-related homicides of US children and adolescents occur at home, particularly affecting younger children, with domestic violence and child abuse as major factors.

Allergy & Immunology Clinical Updates news OB/GYN & Women's Health Specialties

Menopause and Multiple Sclerosis: Evaluating the Impact on Disability Progression

By MedXY 09/29/2025

A comprehensive analysis reveals that menopause does not significantly alter the risk of disability progression in women with relapse-onset multiple sclerosis, underscoring the complexity of reproductive aging's role in disease trajectory.

Pediatrics Public Health Respiratory Specialties

Understanding RSV: Why Immunization Is a Game-Changer for Infants and Vulnerable Adults

By MedXY 09/29/2025

Respiratory Syncytial Virus (RSV) poses serious risks to infants and older adults. Since 2023, RSV immunizations have drastically reduced hospitalizations and deaths. This article explains RSV, symptoms, immunization options, and prevention strategies.

OB/GYN & Women's Health Oncology Specialties

Seventeen Years On: Robust Population-Level Effectiveness and Herd Protection from HPV Vaccination in High-Risk Young Women

By MedXY 09/29/2025

Seventeen years after HPV vaccine introduction, substantial reductions in vaccine-type HPV prevalence confirm strong effectiveness and herd protection among vaccinated and unvaccinated sexually experienced adolescent girls and young women at high risk for HPV.

Clinical Updates Neurology news Specialties

Microbiome Virulence Signatures in the Oral-Gut-Brain Axis: New Insights into Parkinson’s Disease and Cognitive Decline

By MedXY 09/29/2025

This study reveals how virulence factors in oral and gut microbiomes and their translocation affect cognitive impairment in Parkinson’s disease, highlighting novel biomarker potential and the importance of the oral-gut-brain axis for early diagnosis and therapeutic strategies.

Clinical Updates news Ophthalmology Specialties

Nonmedical Factors Impacting Quality of Care in Newly Diagnosed Primary Open-Angle Glaucoma Patients

By MedXY 09/28/2025

This study reveals that socioeconomic status, residential location, and household composition significantly affect treatment outcomes and follow-up in newly diagnosed POAG patients, highlighting the need for targeted strategies to improve glaucoma care equity.

Diabetes & Endocrinology news Ophthalmology Specialties

Acute Angle Closure Incidence in a Large Countywide Safety Net Teleretinal Screening Program: Safety of Pharmacologic Dilation in Diabetic Retinopathy Screening

By MedXY 09/28/2025

This review synthesizes evidence on the incidence of acute angle closure (AAC) following pharmacologic pupillary dilation in a large teleretinal screening program, confirming the very low risk and supporting dilation safety in diverse populations.

AI Hematology-Oncology Medical News news Specialties

Evaluating Anemia-Related YouTube Videos: Reliable Education or Misinformation Risk?

By MedXY 09/28/2025

A recent study assessed the quality, reliability, and popularity of anemia-related videos on YouTube, revealing moderate variability and highlighting the importance of health professionals' involvement to ensure accurate online content.

AI Clinical Updates news Specialties

Evaluating the Clinical Generalizability of FDA-Approved AI-Enabled Medical Devices: Insights and Implications

By MedXY 09/28/2025

A comprehensive analysis of 903 FDA-approved AI medical devices reveals limited clinical performance data and demographic inclusivity, underscoring the need for ongoing evaluation to ensure safe, effective clinical application.

Clinical Updates news Pediatrics Specialties

Clinical Long-Read Sequencing: A Game-Changer in Pediatric Genetic Disease Diagnosis

By MedXY 09/28/2025

Clinical long-read sequencing (LRS) demonstrates superior diagnostic yield and shorter turnaround times compared to standard genetic testing in pediatric genetic diseases, consolidating multiple tests into one comprehensive assay and identifying complex variants missed by traditional methods.

Unraveling the Link Between General Intelligence and Alcohol Use Disorder Risk

Deciphering the Role of Intratumoral Microbiota in Breast Cancer: Pathogenesis to Precision Therapeutics

Novel Heparanase Inhibitor LMW-DSS Shows Promise in Preventing Breast Cancer Metastasis by Targeting Migration and Angiogenesis

Advancing Immunotherapy in Head and Neck Cancer: A Curcumin-Based Polymer Prodrug Nanoplatform Targeting Cancer Stemness and Tumor Microenvironment

Unraveling ADHD: Gut Microbial Signatures and the Role of SCFA Deficiency in Symptom Pathogenesis

Early-Life Gut Microbiome Maturity: A Key Regulator of Blood-Brain Barrier Integrity and Cognitive Development

Restoring Cognitive Function After Adolescent Alcohol Exposure: The Promise of Synbiotic Therapy Targeting the Microbiota-Gut-Brain Axis

NLRP3 Inflammasome and Gut Microbiota-Brain Axis: Emerging Insights into White Matter Injury After Intracerebral Hemorrhage

Preserving Bone Quality in Older Adults with Obesity Through Lifestyle Intervention: Insights from the LIMB-Q Trial

In-Home Firearm Homicides Among Children and Adolescents: Understanding a Hidden Crisis

Menopause and Multiple Sclerosis: Evaluating the Impact on Disability Progression

Understanding RSV: Why Immunization Is a Game-Changer for Infants and Vulnerable Adults

Seventeen Years On: Robust Population-Level Effectiveness and Herd Protection from HPV Vaccination in High-Risk Young Women

Microbiome Virulence Signatures in the Oral-Gut-Brain Axis: New Insights into Parkinson’s Disease and Cognitive Decline

Nonmedical Factors Impacting Quality of Care in Newly Diagnosed Primary Open-Angle Glaucoma Patients

Acute Angle Closure Incidence in a Large Countywide Safety Net Teleretinal Screening Program: Safety of Pharmacologic Dilation in Diabetic Retinopathy Screening

Evaluating Anemia-Related YouTube Videos: Reliable Education or Misinformation Risk?

Evaluating the Clinical Generalizability of FDA-Approved AI-Enabled Medical Devices: Insights and Implications

Clinical Long-Read Sequencing: A Game-Changer in Pediatric Genetic Disease Diagnosis

Mapping the European Cancer Landscape: A 1.7 Million Patient Study Reveals Survival Gaps and Comorbidity Patterns

Prenatal Maternal Depression as a Critical Developmental Risk Factor: Large-Scale IPD Meta-Analysis of 76,514 Children

The Tart Cherry Revolution: A Deep Dive into the Science of Longevity, Recovery, and Restorative Sleep

Restoring Movement: How Polylaminin is Revolutionizing Spinal Cord Injury Treatment