Consistent Improvement in Walking Function Across Diabetes Profiles with Semaglutide in Peripheral Artery Disease: Lessons from the STRIDE Trial
Posted inClinical Updates Diabetes & Endocrinology news Specialties

Consistent Improvement in Walking Function Across Diabetes Profiles with Semaglutide in Peripheral Artery Disease: Lessons from the STRIDE Trial

The STRIDE trial demonstrates that once-weekly semaglutide significantly enhances walking capacity in patients with symptomatic peripheral artery disease and type 2 diabetes, irrespective of baseline diabetes duration, BMI, HbA1c levels, or diabetes medication use.
Top Ten Research Priorities in Menopause: A Comprehensive Evidence-Based Review
Posted inClinical Updates news OB/GYN & Women's Health Specialties

Top Ten Research Priorities in Menopause: A Comprehensive Evidence-Based Review

This review synthesizes the Menopause Priority Setting Partnership findings, highlighting the top ten evidence-based research priorities addressing non-hormonal treatments, lifestyle interventions, cognitive and sleep changes, hormone therapy duration, global experiences, breast cancer management, dementia risk, and personalized hormone therapy safety.
Surgical Management of Left-Sided Infective Endocarditis: Insights from the Nationwide NIDUS Registry
Posted inCardiology Clinical Updates General Surgery news Specialties

Surgical Management of Left-Sided Infective Endocarditis: Insights from the Nationwide NIDUS Registry

A nationwide Danish study reveals that while 40% of left-sided infective endocarditis patients have surgical indications, only half undergo surgery. Those receiving surgery are younger, less comorbid, and show improved survival, underscoring the need for refined risk assessment in high-risk cases.
Targeted Reduction of Sitting Time Versus Increased Sit-to-Stand Transitions: Effects on Blood Pressure and Glucose Regulation in Postmenopausal Women
Posted inCardiology Clinical Updates Diabetes & Endocrinology Family Medicine & Nutrition news OB/GYN & Women's Health Specialties

Targeted Reduction of Sitting Time Versus Increased Sit-to-Stand Transitions: Effects on Blood Pressure and Glucose Regulation in Postmenopausal Women

A 3-month randomized trial in overweight postmenopausal women found that increasing sit-to-stand transitions significantly reduces diastolic blood pressure, while reducing total sitting time alone does not improve blood pressure or glucoregulatory measures.
High-Dose vs Standard-Dose Influenza Vaccine in Older Adults: Insights from the DANFLU-2 Randomized Clinical Trial
Posted inClinical Updates Internal Medicine news Public Health Respiratory Specialties

High-Dose vs Standard-Dose Influenza Vaccine in Older Adults: Insights from the DANFLU-2 Randomized Clinical Trial

The DANFLU-2 trial demonstrates that high-dose influenza vaccine reduces cardiovascular and cardiorespiratory hospitalizations compared to standard-dose in adults ≥65 years, with similar benefits across subgroups including heart failure and atherosclerotic cardiovascular disease.
Real-World Insights into Clinical Presentation and Surgical Outcomes of Mitral Regurgitation from the MITRACURE Registry
Posted inCardiology Clinical Updates General Surgery news Specialties

Real-World Insights into Clinical Presentation and Surgical Outcomes of Mitral Regurgitation from the MITRACURE Registry

The MITRACURE international registry reveals that mitral valve surgery patients often present late in disease progression with advanced symptoms, showing modest repair rates and notable in-hospital mortality, underscoring the need for earlier intervention and improved management strategies.