A randomized trial shows that a smartphone-based asthma self-management program improves symptom control in adults, though its effectiveness is attenuated in African American participants.
A new, function-driven definition of “clinical obesity” dramatically lowers global obesity prevalence rates compared to BMI-based estimates, raising implications for disease surveillance, prevention, and healthcare policy.
A 29-year genomic study reveals increasing genetic diversity and prevalence of triazole-resistant Aspergillus fumigatus, raising concerns for clinical management and highlighting the need for novel diagnostics and antifungal strategies.
Discovery of genetically conserved, mutation-intolerant HIV peptides in rebound virus during analytic treatment interruption highlights new avenues for mRNA vaccine development and functional HIV cure strategies.
Massachusetts General Hospital leads the 2025-2026 US News psychiatric hospital rankings. Rankings highlight excellence in psychiatric care, but methodological nuances and clinical implications warrant closer examination.
Patients with inflammatory bowel disease (IBD), particularly those with primary sclerosing cholangitis (PSC) or early-onset disease, face a substantially increased risk of colorectal cancer (CRC), emphasizing the need for vigilant surveillance.
Antibody-drug conjugates (ADCs) have transformed breast cancer therapy but bring notable toxicity risks. This review examines the clinical evidence, adverse event management, and future directions for optimizing ADC use.
Once-weekly lonapegsomatropin (Skytrofa) is now FDA-approved for adult growth hormone deficiency, offering a more convenient alternative to daily injections with demonstrated efficacy and safety.
Emerging evidence links subclinical primary aldosteronism to significantly increased cardiovascular risk, even in normotensive individuals, highlighting the need for refined screening and personalized hypertension management.
Audit reveals major misclassification in hospital coding for myocardial infarction types, risking flawed epidemiology, reimbursement, and patient care.
A 12-week randomized trial finds that increasing daily sit-to-stand transitions reduces diastolic blood pressure in sedentary, overweight, or obese postmenopausal women but does not significantly affect glucose regulation.
Explore the methodology and significance of the 2025-2026 U.S. News Best Hospitals rankings, featuring top-performing hospitals nationwide and the criteria driving their recognition.
Emerging research reveals that prenatal exposure to fine particulate air pollution (PM2.5) may significantly increase a child’s risk of developing obesity, spotlighting pregnancy as a critical window for future health.
A groundbreaking trial highlights how hybrid closed-loop systems improve glycemic control for pregnant women with type 1 diabetes, offering enhanced maternal and fetal health outcomes.