Subglottic Suction and Polyurethane Cuffs Fail to Improve Outcomes in Emergency Intubation: Insights from the PreVent 2 Trial

Subglottic Suction and Polyurethane Cuffs Fail to Improve Outcomes in Emergency Intubation: Insights from the PreVent 2 Trial

The PreVent 2 trial demonstrates that specialized endotracheal tubes with subglottic suction and polyurethane cuffs do not significantly reduce ventilator-associated complications or improve 6-month laryngeal, cognitive, or quality-of-life outcomes compared to standard PVC tubes in emergency settings.
ICU Structure and Care Processes Drive VAP and CLABSI Burden in Brazilian ICUs: Insights from the IMPACTO‑MR Nested Cohort

ICU Structure and Care Processes Drive VAP and CLABSI Burden in Brazilian ICUs: Insights from the IMPACTO‑MR Nested Cohort

A large multicenter Brazilian cohort found that ICU-level structure and process measures — staffing, prevention protocols, hand hygiene training, visitation policies, and specific clinical roles — explain substantial between-hospital variability and are associated with lower VAP and CLABSI rates.