Traumatic Brain Injury

Rising Hospital Mortality and Escalating Rates of Life-Sustaining Therapy Withdrawal in Critically Ill TBI Patients: A 15-Year Analysis

By MedXY 12/19/2025

A 15-year observational study of over 45,000 TBI patients reveals a significant increase in hospital mortality and a tripling of life-sustaining therapy withdrawal, alongside rising rates of hypoxaemia, raising urgent questions about ethical frameworks and neurocritical care management.

Critical Care Emergency Medicine Neurology news

Prehospital Postintubation Hypotension Strongly Linked to 30‑Day Mortality After Severe Traumatic Brain Injury — Especially in Isolated TBI

By MedXY 12/15/2025

A multicenter cohort study of 555 patients with severe TBI who underwent prehospital rapid sequence induction found postintubation hypotension (SBP <90 mmHg within 10 minutes) in 19.1%, which was associated with higher 30‑day mortality (AOR 1.70). The association was markedly stronger in isolated TBI (AOR 13.55).

General Surgery Neurology Rehabilitation Medicine Specialties

Impact of Early Extracranial Surgery on One-Year Outcomes After Traumatic Brain Injury: Insights from the TRACK-TBI Study

By MedXY 10/21/2025

Early extracranial surgery following moderate-severe traumatic brain injury or positive CT findings is linked to worse cognitive, functional, and quality of life outcomes at one year, highlighting the need to refine surgical timing and post-injury interventions.

Emergency Medicine news Psychiatry

Which Mental-Health Steps Should Trauma Teams Prioritize? A Practical Synthesis of New Guideline Recommendations

By MedXY 10/10/2025

A systematic synthesis of clinical practice guideline recommendations for preventing and managing mental disorders after traumatic injury, with prioritized, implementable actions for acute and early recovery care.

Neurology news Public Health

Unraveling the Link Between Traumatic Brain Injury and ALS Risk: Insights From a Large UK Cohort Study

By MedXY 10/05/2025

A large retrospective cohort study reveals a transient association between traumatic brain injury (TBI) and elevated amyotrophic lateral sclerosis (ALS) risk, suggesting early ALS symptoms may predispose to injury rather than TBI causing ALS.

Neurology news

Balancing Act in Traumatic Acute Subdural Hematoma: Acute Surgery vs Conservative Management

By MedXY 10/04/2025

A multicenter study found no superior outcomes between acute surgical evacuation and conservative treatment for traumatic acute subdural hematoma, suggesting conservative management may be appropriate when surgical equipoise exists.

Neurology news Specialties

Sex-Specific Brain Volume Loss After Traumatic Brain Injury: Greater Impact in Older Women

By MedXY 07/31/2025

A study from the Framingham Heart Study cohort reveals that traumatic brain injury (TBI) is linked to significant brain volume loss in older women but not men, highlighting sex-specific vulnerability to neurodegeneration post-TBI.