testosterone – Medxy AI

Testosterone and Weight Loss: Decoding the Link Between Sex Hormones and Cardiovascular Risk in Men with Type 2 Diabetes

By MedXY 03/09/2026

A longitudinal analysis of the Look AHEAD trial demonstrates that baseline testosterone and weight loss-induced changes in SHBG significantly modulate cardiovascular risk in men with type 2 diabetes, highlighting the critical role of hormonal health in metabolic management.

news Orthopedics Rehabilitation Medicine

Higher Endogenous Testosterone Is Associated with Lower Risk of Knee Osteoarthritis in Women

By MedXY 11/02/2025

In a large UK Biobank cohort, higher circulating testosterone was associated with lower prevalent and incident knee osteoarthritis (KOA) in middle-aged and older women, while SHBG and estradiol showed no clear associations.

Clinical Updates news Specialties Urology

Testosterone Therapy in Middle-Aged and Older Men with Hypogonadism: Balancing Clinical Benefits and Risks

By MedXY 08/07/2025

Testosterone therapy offers modest benefits for sexual function, anemia, and bone health in older men with hypogonadism, but increases risks of venous thromboembolism, fractures, and arrhythmias. Careful patient selection and individualized risk-benefit assessment are essential.