resuscitation – Medxy AI

Albumin Replacement in Septic Shock: Safety Confirmed but Survival Benefit Remains Elusive

By MedXY 02/23/2026

The ARISS randomized clinical trial found that 20% albumin supplementation to maintain serum levels ≥3.0 g/dL is safe in septic shock but does not significantly improve 90-day survival compared to standard crystalloids, though the study's early termination limits its definitive power.

Critical Care news Pediatrics

Rethinking Oxygen Strategies for Preterm Infant Resuscitation: Evidence from TORPIDO, IPD-MA, and DCC Trials

By MedXY 12/16/2025

Recent trials and meta-analyses challenge assumptions about optimal initial oxygen levels for preterm resuscitation.

Critical Care news

Targeting Tissue Perfusion and Lower MAP in Septic Shock Did Not Improve 30‑Day Perfusion-Free Survival: Results from the TARTARE-2S Randomized Trial

By MedXY 12/10/2025

In the TARTARE-2S trial, a tissue-perfusion–guided resuscitation strategy that permitted lower MAP (50–65 mm Hg) did not increase days alive with normalized lactate and without vasopressors at 30 days versus standard-of-care MAP-guided treatment in septic shock.