randomized clinical trial – Page 2

Smart-T Digital Intervention Enhances Smoking Cessation Among Low-Income Adults: Insights from a Randomized Clinical Trial

By MedXY 09/11/2025

The Smart-T smartphone intervention significantly improves 7-day smoking abstinence at 26 weeks in low-income adults, outperforming the standard QuitGuide app when combined with nicotine replacement therapy.

Clinical Updates news Psychiatry Specialties

Cannabidiol Use and Liver Enzyme Elevations: Insights from a Randomized Clinical Trial in Healthy Adults

By MedXY 09/11/2025

A 4-week randomized trial shows that low-dose cannabidiol (CBD) may cause transient liver enzyme elevations in healthy adults, emphasizing the need for vigilance and further safety assessment of consumer CBD products.

Clinical Updates news

Metformin and COVID-19 Symptom Resolution: Evidence from the ACTIV-6 Randomized Clinical Trial

By MedXY 09/11/2025

This review synthesizes recent evidence from the ACTIV-6 trial showing metformin does not significantly reduce symptom duration in low-risk adults with COVID-19, addressing safety, clinical outcomes, and translational insights.

General Surgery news OB/GYN & Women's Health Specialties

Open Anterior Mesh Repair Versus Modified Technique for Groin Hernia in Women: Insights from a Ugandan Randomized Trial

By MedXY 09/11/2025

A randomized clinical trial in Uganda compared standard open anterior mesh repair with a modified technique addressing femoral hernias, demonstrating both methods as safe and effective options for women's groin hernia repair in low-resource settings.

Clinical Updates Infectious Diseases Respiratory Specialties

Evaluating Germicidal UV Light to Reduce Respiratory Infections in Long-Term Care: Insights from a South Australian Randomized Trial

By MedXY 09/10/2025

A randomized clinical trial in South Australian long-term care facilities found germicidal UV light appliances did not significantly reduce acute respiratory infection rates per cycle but modestly lowered total infections over time, suggesting a supportive role in infection control.

Clinical Updates Dermatology news Nursing & care Pediatrics Specialties

Daily Emollient Use in Infants: A Promising Strategy to Prevent Pediatric Atopic Dermatitis

By MedXY 09/03/2025

A large pragmatic trial demonstrates that daily emollient application starting before 9 weeks of age significantly reduces the risk of atopic dermatitis by 24 months in infants not selected for high risk, offering a feasible preventive approach in pediatric dermatology.

Cardiology Clinical Updates General Surgery news Specialties

Reducing Infection Risk in Repeat CIED Surgery with Iodine-Impregnated Drapes: Insights from a Randomized Clinical Trial

By MedXY 08/31/2025

A randomized trial demonstrates that iodine-impregnated drapes significantly reduce pocket contamination and cardiac implantable electronic device infections in repeat surgeries, offering a simple, cost-effective prophylactic intervention.

Clinical Updates Pediatrics Public Health Specialties

Varenicline Significantly Enhances Nicotine Vaping Cessation in Youth: Insights from a Landmark Randomized Clinical Trial

By MedXY 08/25/2025

A randomized clinical trial demonstrates that varenicline, combined with behavioral counseling, markedly improves nicotine vaping cessation rates in youth aged 16-25 who vape daily and do not regularly smoke tobacco.

Clinical Updates Oncology Radiology Specialties

Sequential Chemoradiotherapy vs Induction Plus Concurrent Chemoradiotherapy in Locoregionally Advanced Nasopharyngeal Carcinoma: Efficacy and Safety Insights from a Phase 3 Randomized Trial

By MedXY 08/23/2025

A multicenter phase 3 trial demonstrates that sequential chemoradiotherapy is noninferior to induction plus concurrent chemoradiotherapy for stage III/IVA nasopharyngeal carcinoma with fewer acute toxicities.

AI news Psychiatry Public Health Specialties

Digital Therapeutics in Suicide Prevention: Evidence and Clinical Implications of a Smartphone-Based CBT Intervention

By MedXY 08/20/2025

Smartphone-delivered cognitive-behavioral therapy (CBT) via a digital therapeutic app significantly reduces recurrent suicide attempts and sustains reduction in suicidal ideation among adults with prior suicide attempts.

Clinical Updates Neurology news Orthopedics Specialties

Modern Pain Neuroscience Approach Versus Usual Care in Chronic Whiplash Disorders: Evidence from a Randomized Clinical Trial

By MedXY 08/19/2025

This review analyzes a randomized clinical trial comparing modern pain neuroscience approach and usual care physiotherapy in chronic whiplash disorders, highlighting immediate and 12-month improvements, cost-effectiveness, and benefits in anxiety and central sensitization symptoms with MPNA.