prognosis – Medxy AI

Ultrasensitive Circulating Tumor DNA as a Superior Biomarker for Remission Assessment in Large B-cell Lymphoma

By MedXY 09/10/2025

Detection of circulating tumor DNA (ctDNA) provides a highly prognostic method for assessing remission in large B-cell lymphoma, outperforming conventional imaging and promising improved patient outcomes.

Clinical Updates Wellness & Lifestyle

Prognostic Role of HER2 Amplification and Mutations in Metastatic Colorectal Cancer: Insights from Eight Randomized Trials

By MedXY 09/10/2025

HER2 amplification/mutation in RAS/BRAF wild-type metastatic colorectal cancer is a negative prognostic factor but does not predict differential benefit from bevacizumab or anti-EGFR therapies, based on analysis of 1,604 patients across eight randomized trials.

Clinical Updates Wellness & Lifestyle

Unraveling the Prognostic Impact of Co-Occurring High-Risk Cytogenetic Abnormalities in Multiple Myeloma

By MedXY 09/09/2025

A meta-analysis of 24 trials involving 13,926 patients establishes that concurrent high-risk cytogenetic abnormalities markedly worsen progression-free and overall survival in both newly diagnosed and relapsed multiple myeloma, underscoring the need for targeted therapeutic strategies.

Clinical Updates Wellness & Lifestyle

Top Ten Essential Tips for Palliative Care Clinicians Consulting in Intensive Care Units

By MedXY 09/07/2025

This article provides ten practical tips for palliative care clinicians to optimize consultation effectiveness in ICUs, emphasizing collaboration, communication, cultural respect, conflict resolution, and transition planning to improve patient and family outcomes.

Clinical Updates Wellness & Lifestyle

Exercise Echocardiography for Cardiac Output Reserve in Fontan Physiology: Feasibility, Reproducibility, and Prognostic Insights

By MedXY 09/06/2025

Exercise echocardiography reliably assesses cardiac output reserve in adults with Fontan circulation, revealing impaired reserve linked to congestion and adverse cardiovascular events, thereby offering valuable prognostic information beyond conventional measures.

Clinical Updates Wellness & Lifestyle

T-ICAHT: A New Grading System for Thrombocytopenia After CAR T-cell Therapy with Prognostic Significance

By MedXY 08/29/2025

A novel grading system, T-ICAHT, quantifies thrombocytopenia after CAR T-cell therapy, revealing its prevalence and prognostic impact, highlighting its value in patient management and outcome prediction across hematologic malignancies.

Clinical Updates Wellness & Lifestyle

Anticoagulant therapy for cancer-associated splanchnic vein thrombosis: Outcomes during a one-year follow-up period

By MedXY 08/26/2025

This study evaluates one-year outcomes in cancer-associated splanchnic vein thrombosis, showing anticoagulation increases recanalization and bleeding risk but offers no survival benefit, highlighting tumor thrombus and metastasis as key mortality predictors.

Clinical Updates Wellness & Lifestyle

Clinical Presentation, Management, and Outcomes of 11,132 Liposarcoma Patients: Insights from the NETSARC+ Registry

By MedXY 08/22/2025

The NETSARC+ registry study comprehensively characterizes liposarcoma histotypes, revealing diverse clinical presentations, management strategies, and prognoses, with dedifferentiated liposarcoma having the poorest survival and age-sex specific prognostic differences.

Clinical Updates Wellness & Lifestyle

Hypervitaminosis B12 and Mortality Risk: Unraveling the Controversy Through a Global Systematic Review and Meta-Analysis

By MedXY 08/18/2025

A comprehensive meta-analysis reveals that elevated serum vitamin B12 levels do not conclusively predict increased all-cause mortality risk in adults, highlighting the complexity and heterogeneity of existing research.

Clinical Updates Wellness & Lifestyle

Dual Biomarker Strategy: Enhancing Prognosis in Acute Heart Failure with CA125 and NT-proBNP in Vietnam

By MedXY 08/08/2025

Combining CA125 with NT-proBNP significantly improves prediction of cardiovascular and all-cause mortality, as well as rehospitalization risk in patients with acute heart failure.

$Explainable Artificial Intelligence for Predicting Refractory Ulcerative Colitis: Insights from a Japanese Nationwide Registry$

Clinical Updates Wellness & Lifestyle

Explainable Artificial Intelligence for Predicting Refractory Ulcerative Colitis: Insights from a Japanese Nationwide Registry

By MedXY 08/07/2025

A machine learning model using nationwide registry data accurately predicts long-term remission in refractory ulcerative colitis and identifies key prognostic factors such as pseudopolyps.

Clinical Updates Wellness & Lifestyle

Type II Cryoglobulinemic Vasculitis: A Marker of Severe Prognosis in Primary Sjögren Disease

By MedXY 08/06/2025

A French multicenter study identifies type II cryoglobulinemic vasculitis in primary Sjögren disease as a strong predictor of lymphoma and mortality, necessitating enhanced clinical vigilance.

Clinical Updates Wellness & Lifestyle

Young COPD: Prevalence and Prognostic Impact in Adults Under 50 Years

By MedXY 08/05/2025

COPD in adults under 50 affects 4.5% of this population and is linked to increased risks of early mortality and serious cardiopulmonary events, underscoring the need for early identification and intervention.