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Personalized Prediction of Platelet Transfusion Outcomes in Preterm Infants with Severe Thrombocytopenia
Posted inHematology-Oncology Pediatrics Specialties

Personalized Prediction of Platelet Transfusion Outcomes in Preterm Infants with Severe Thrombocytopenia

Posted by By MedXY 10/14/2025
A dynamic model predicts individualized risk of major bleeding or death with or without prophylactic platelet transfusion in preterm infants, allowing tailored clinical decisions based on evolving patient status.
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Evaluating Early Intratracheal Budesonide to Reduce Bronchopulmonary Dysplasia in Extremely Preterm Infants: Insights from the BiB Randomized Clinical Trial
Posted innews Pediatrics Respiratory

Evaluating Early Intratracheal Budesonide to Reduce Bronchopulmonary Dysplasia in Extremely Preterm Infants: Insights from the BiB Randomized Clinical Trial

Posted by By MedXY 10/10/2025
The BiB trial showed that adding budesonide to surfactant did not reduce bronchopulmonary dysplasia or death in extremely preterm infants but was associated with increased hyperglycemia risk.
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Enhanced Respiratory Support in Very Preterm Infants: Nasal Mask CPAP Outperforms Face Mask at Birth
Posted innews Pediatrics Specialties

Enhanced Respiratory Support in Very Preterm Infants: Nasal Mask CPAP Outperforms Face Mask at Birth

Posted by By MedXY 09/21/2025
An open-label RCT demonstrates that nasal mask CPAP at birth increases CPAP success rates and reduces the need for positive pressure ventilation compared to face mask CPAP in very preterm infants, with comparable safety profiles.
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Deferred Cord Clamping with High Oxygen in Extremely Preterm Infants: Enhancing Early Oxygenation Without Added Morbidity
Posted inClinical Updates news Pediatrics Specialties

Deferred Cord Clamping with High Oxygen in Extremely Preterm Infants: Enhancing Early Oxygenation Without Added Morbidity

Posted by By MedXY 09/10/2025
This review examines randomized clinical evidence that 100% oxygen during deferred cord clamping improves early oxygen saturation in extremely preterm infants without increasing morbidity, highlighting implications for neonatal resuscitation practice.
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Darbepoetin in Preterm Infants: Enhancing Red Cell Mass without Neurodevelopmental Benefit
Posted inClinical Updates news Pediatrics Specialties

Darbepoetin in Preterm Infants: Enhancing Red Cell Mass without Neurodevelopmental Benefit

Posted by By MedXY 08/04/2025
Weekly darbepoetin in extremely preterm infants increases red cell mass and reduces transfusion needs, but does not improve cognitive outcomes at 22-26 months' corrected age.
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Supplemental Donor Milk versus Infant Formula for Moderate to Late Preterm Infants: Implications from a Multisite Randomized Trial
Posted inClinical Updates Family Medicine & Nutrition news Pediatrics Specialties

Supplemental Donor Milk versus Infant Formula for Moderate to Late Preterm Infants: Implications from a Multisite Randomized Trial

Posted by By MedXY 08/04/2025
A multisite RCT found no difference in time to full enteral feeds between donor human milk and formula in moderate to late preterm infants, but formula was associated with faster weight regain.
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Perinatal Antibiotic Exposure Alters Neonatal Gut Microbiota in Preterm Infants: Clinical Implications for Infection Risk and Microbial Maturation
Posted inClinical Updates news

Perinatal Antibiotic Exposure Alters Neonatal Gut Microbiota in Preterm Infants: Clinical Implications for Infection Risk and Microbial Maturation

Posted by By MedXY 08/04/2025
Perinatal antibiotic exposure in preterm infants disrupts gut microbiota composition, increasing pathogenic bacteria and reducing beneficial species, with implications for infection risk and the protective role of breastfeeding.
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