Pregnancy – Medxy AI

Pregnancy DMT Management in Multiple Sclerosis Increases Relapse Risk — Anti‑CD20 Before Conception Is Most Protective

By MedXY 12/11/2025

A large French registry study shows that how disease-modifying therapies (DMTs) are managed during pregnancy meaningfully affects relapse rates in relapsing‑onset MS; prolonged natalizumab interruption and fingolimod use carry the highest risks, while preconception anti‑CD20 strategies are most protective.

news Public Health

Wildfire Smoke During Pregnancy Linked to Higher Preterm Birth Risk in the US West: ECHO Cohort Analysis Shows Intensity, Duration, and Timing Matter

By MedXY 11/23/2025

A nationwide ECHO analysis found wildfire-specific PM2.5 exposure was associated with increased odds of preterm birth in the US West, with stronger effects for higher concentration, longer smoke waves, and mid-to-late pregnancy exposures.

news Pediatrics

Maternal Paracetamol in Pregnancy and Child Neurodevelopment: Current Evidence Does Not Establish a Clear Causal Link

By MedXY 11/22/2025

An umbrella review of systematic reviews finds low to critically low confidence in studies linking prenatal paracetamol exposure to autism or ADHD; sibling-controlled analyses largely attenuate associations. Clinical guidance: use lowest effective dose for clear indications and avoid unnecessary prolonged use.

HIV/AIDS news OB/GYN & Women's Health

Dapivirine Ring and Oral PrEP in Pregnancy: MTN-042/DELIVER Shows Infant Safety Through 12 Months

By MedXY 11/12/2025

A randomized phase 3b trial found no infant safety signals attributable to in-utero exposure to the dapivirine vaginal ring or oral tenofovir–emtricitabine PrEP over 12 months of follow-up, supporting use of both options for HIV prevention in pregnancy.

news Psychiatry

Treatment Retention in Opioid Use Disorder During Pregnancy: Buprenorphine vs Methadone Discontinuation Patterns

By MedXY 10/30/2025

This nationwide cohort study reveals higher discontinuation rates of buprenorphine than methadone during pregnancy and up to one year postpartum, highlighting significant challenges in treatment retention for opioid use disorder in pregnant patients.

Diabetes & Endocrinology OB/GYN & Women's Health

Closed-Loop Insulin Delivery in Type 1 Diabetes During Pregnancy: Insights from the CIRCUIT Randomized Clinical Trial and Contemporary Evidence

By MedXY 10/24/2025

The CIRCUIT trial demonstrates that closed-loop insulin delivery significantly improves glycemic control during pregnancy in type 1 diabetes, increasing time in pregnancy-specific glucose range and reducing hypoglycemia risks relative to standard care.

OB/GYN & Women's Health Psychiatry Specialties

Hyperemesis Gravidarum and Depression: Unveiling the Bidirectional Link

By MedXY 10/18/2025

This comprehensive review examines the recent Finnish study highlighting the complex relationship between hyperemesis gravidarum and depression, emphasizing clinical implications for integrated mental health screening during reproductive care.

Allergy & Immunology Clinical Updates OB/GYN & Women's Health

Pregnancy and Disease Outcomes in Women with Moderate to Severe Multiple Sclerosis Disability

By MedXY 09/24/2025

This study evaluates how pregnancy affects relapse rates and long-term disability in women with moderate to severe multiple sclerosis (MS), showing pregnancy reduces relapse during gestation without worsening long-term disability progression.

Clinical Updates OB/GYN & Women's Health Oncology Specialties

Breastfeeding After Hormone Receptor-Positive Breast Cancer: Insights From the POSITIVE Trial

By MedXY 09/09/2025

The POSITIVE trial reveals that two thirds of women with early hormone receptor-positive breast cancer successfully breastfed post-treatment, without a significant increase in cancer recurrence risk, offering reassurance to women considering pregnancy and breastfeeding after breast cancer.

Diabetes & Endocrinology news OB/GYN & Women's Health Specialties

Impact of Maternal Trace Element Levels on Neonatal Growth Among Diabetic and Non-Diabetic Pregnancies

By MedXY 08/30/2025

A case–control study reveals that elevated copper levels in diabetic pregnant women negatively affect newborn weight and head circumference, while chromium correlates positively with birth length. Smoking exposure adversely impacts infants’ weight, underscoring maternal trace element status and lifestyle as key determinants of neonatal outcomes.

Clinical Updates news OB/GYN & Women's Health Specialties

The Microcirculation in Pregnancy: Guardian of Health or Victim of Preeclampsia?

By MedXY 08/13/2025

This article explores how microcirculation functions as a key regulator in normal pregnancy but is compromised in preeclampsia, revealing early hemodynamic mechanisms behind gestational hypertension.

Family Medicine & Nutrition news Specialties

Seven Groups Who Should Avoid Fish Oil: Essential Precautions You Must Know

By MedXY 08/08/2025

Fish oil offers health benefits but is not suitable for everyone. Learn about the seven groups who should avoid fish oil to prevent health risks and ensure safe supplement use.

Allergy & Immunology news OB/GYN & Women's Health Specialties

Managing Allergies During Pregnancy: Key Tips for Expectant Mothers

By MedXY 08/06/2025

Explore how pregnant women can manage allergies to pollen, dust mites, and pet dander effectively to ensure health and comfort for themselves and their babies.

news OB/GYN & Women's Health Specialties

How to Manage Irritability and Mood Swings During Pregnancy

By MedXY 08/06/2025

Pregnancy can cause mood swings and irritability due to hormonal changes. This article explores causes and practical strategies to manage emotional ups and downs for expectant mothers.

Allergy & Immunology Clinical Updates news Rheumatology Specialties

Therapeutic Strategies for Disease-Modifying Therapy Management in Pregnant Women With Multiple Sclerosis: Relapse Risk and Clinical Implications

By MedXY 08/04/2025

Managing disease-modifying therapies (DMTs) during pregnancy in women with multiple sclerosis significantly affects relapse risk, with anti-CD20 strategies demonstrating superior protection compared to other approaches.

Clinical Updates news OB/GYN & Women's Health Pediatrics Specialties

Trimethoprim–Sulfamethoxazole in Pregnancy: No Impact on Birth Weight in a Zimbabwean RCT

By MedXY 08/01/2025

A large randomized trial in Zimbabwe found that trimethoprim–sulfamethoxazole prophylaxis during pregnancy did not significantly increase birth weight or reduce adverse outcomes.

Medical News news Public Health Specialties

CDC Retracts Universal COVID-19 Vaccination Recommendation for Pregnancy: Clinical Context, Evidence, and Implications

By MedXY 07/30/2025

The CDC no longer universally recommends COVID-19 vaccination during pregnancy, prompting debate among clinicians as the FDA shifts vaccine composition to target the JN.1 variant. This article analyzes the evidence, rationale, and clinical implications.

Clinical Updates news OB/GYN & Women's Health Specialties

Evolving Patterns in Antiseizure Drug Use During Pregnancy: Safer Choices and New Uncertainties

By MedXY 07/30/2025

A decade-long French study reveals declining prenatal exposure to high-risk antiseizure drugs, increased use of safer alternatives, and a notable rise in prescriptions for newer drugs with uncertain safety profiles.

Medical News OB/GYN & Women's Health Psychiatry Specialties

FDA Panel Reviews SSRI Use During Pregnancy: Balancing Fetal Risks and Maternal Mental Health

By MedXY 07/29/2025

An FDA expert panel debates the risks and benefits of SSRI antidepressants in pregnancy, emphasizing the need to weigh untreated depression risks against potential drug-related fetal outcomes.

news OB/GYN & Women's Health Specialties

Gut Microbiota and Pregnancy Risks: the Connection in Polycystic Ovary Syndrome

By MedXY 07/29/2025

Scientific findings link imbalances in gut microbiota and metabolic markers to pregnancy complications in women with PCOS.