PCOS – Medxy AI

Undiagnosed Hyperandrogenism in Type 1 Diabetes: Clinical Evidence, Mechanisms, and Screening Implications

By MedXY 12/27/2025

Recent evidence reveals that one in four premenopausal women with Type 1 diabetes (T1D) suffers from undiagnosed androgen excess disorders, primarily the classic PCOS phenotype, necessitating routine screening and a recalibration of reproductive healthcare in diabetic management.

Diabetes & Endocrinology news OB/GYN & Women's Health

One in Four Premenopausal Women with Type 1 Diabetes Faces Undiagnosed Androgen Excess Disorders

By MedXY 12/27/2025

A cross-sectional study reveals that 26% of women with Type 1 Diabetes suffer from undiagnosed androgen excess, primarily PCOS. The findings emphasize the role of iatrogenic hyperinsulinism and advocate for routine screening, especially for those with premenarcheal diabetes onset.

Diabetes & Endocrinology news

PCOS as a Biological Model for Reproductive Longevity: Enhanced Ovarian Reserve and ART Success in Aging Asian Women

By MedXY 12/25/2025

A retrospective study of 1,249 Asian women reveals that those with PCOS maintain superior ovarian reserve and stable cumulative pregnancy rates via ART even after age 36, suggesting PCOS may serve as a biological model for extended reproductive longevity.

Diabetes & Endocrinology news

Liraglutide Plus Metformin in Overweight/Obese PCOS: Greater Metabolic and Hormonal Benefits Than Metformin Alone

By MedXY 11/17/2025

A 2025 meta-analysis of 19 RCTs (n=1657) found liraglutide combined with metformin improved glycaemia, insulin resistance, BMI, sex hormones and lipids versus metformin alone in overweight or obese women with PCOS; evidence certainty was low due to heterogeneity and risk of bias.

Diabetes & Endocrinology news

Liraglutide Plus Metformin in Overweight/Obese PCOS: Greater Metabolic and Hormonal Benefits Than Metformin Alone

By MedXY 11/17/2025

Diabetes & Endocrinology news

Tirzepatide Produces Large Real‑World Weight Loss in Women with PCOS

By MedXY 11/14/2025

A large retrospective real‑world cohort (n=4241) of women with PCOS and overweight/obesity treated with tirzepatide experienced mean 18.8% weight loss at 10 months (90% lost ≥10%); digital engagement amplified outcomes. The data are promising but require randomized, biomarker‑driven studies to define metabolic and reproductive benefits and safety in this population.

Diabetes & Endocrinology news OB/GYN & Women's Health Specialties

Enhanced Therapeutic Benefits of Combined Metformin and Curcumin in Women with Polycystic Ovary Syndrome: Results from a Factorial Clinical Trial

By MedXY 09/16/2025

A 12-week randomized trial demonstrates that combining metformin and nanocurcumin significantly improves lipid metabolism, glucose regulation, hormonal balance, and body metrics in women with PCOS, surpassing effects seen with either agent alone or placebo.

Clinical Updates news OB/GYN & Women's Health Specialties

Enhanced Therapeutic Outcomes in Overweight/Obese Women with PCOS: Combining Metformin and Semaglutide

By MedXY 09/16/2025

Combination therapy with metformin and semaglutide improves weight loss, metabolic parameters, menstrual function, and natural pregnancy rates in overweight/obese women with PCOS compared to metformin alone.

news OB/GYN & Women's Health Specialties

Gut Microbiota and Pregnancy Risks: the Connection in Polycystic Ovary Syndrome

By MedXY 07/29/2025

Scientific findings link imbalances in gut microbiota and metabolic markers to pregnancy complications in women with PCOS.

news OB/GYN & Women's Health Specialties

Exploring Sexual Function in Women with PCOS: Insights from Recent Research

By MedXY 07/28/2025

A systematic review assesses sexual function in women with PCOS, revealing impaired psychosexual function and calling for more diverse and comprehensive studies.

news OB/GYN & Women's Health Specialties

Navigating the Complex World of PCOS: A Gender-Diverse Perspective

By MedXY 07/28/2025

Exploring the unique experiences of gender-diverse individuals with PCOS and its impact on gender identity.

news OB/GYN & Women's Health Specialties

Understanding Idiopathic Hirsutism: A Misnomer in Medical Science?

By MedXY 07/28/2025

Idiopathic hirsutism, characterized by excessive hair growth, may not be truly idiopathic. Research suggests underlying androgen mechanisms could redefine its classification.