neurodegeneration

Diabetes and Dementia Biomarkers: Less Alzheimer’s Pathology but More Non‑AD Neurodegeneration in Cognitively Normal Adults

By MedXY 11/04/2025

A pan‑European analysis (n=5,550) found diabetes was associated with lower odds of amyloid and p‑tau pathology in cognitively impaired patients, but with markers of neurodegeneration (total tau, medial temporal atrophy) in cognitively normal individuals without amyloid — suggesting non‑AD pathways link diabetes to cognitive decline.

Neurology news

Advances in Alzheimer’s Diagnosis: A Comprehensive Review of CSF and Blood Biomarkers

By MedXY 10/20/2025

This article reviews a systematic meta-analysis of 15 cerebrospinal fluid and blood biomarkers for Alzheimer's disease, highlighting robust diagnostic performance of core markers T-tau, P-tau, and Aβ42 in clinical practice and research.

Neurology news

Simvastatin Fails to Slow Disability Progression in Secondary Progressive Multiple Sclerosis: Insights from the Phase 3 MS-STAT2 Trial

By MedXY 10/10/2025

In a large phase 3 trial, simvastatin 80 mg daily did not reduce disability progression in secondary progressive multiple sclerosis, challenging prior phase 2 results and underscoring the complexity of neurodegeneration in SPMS.

Neurology news Public Health

Unraveling the Link Between Traumatic Brain Injury and ALS Risk: Insights From a Large UK Cohort Study

By MedXY 10/05/2025

A large retrospective cohort study reveals a transient association between traumatic brain injury (TBI) and elevated amyotrophic lateral sclerosis (ALS) risk, suggesting early ALS symptoms may predispose to injury rather than TBI causing ALS.

Family Medicine & Nutrition Medical News news

Reversing Brain Aging in Just 24 Hours: The Powerful Synergy of Nicotinamide and Green Tea

By MedXY 09/20/2025

A groundbreaking study reveals that nicotinamide and green tea polyphenols can restore brain energy and cellular cleanup mechanisms within 24 hours, potentially reversing neurodegeneration and improving cognitive function.

Clinical Updates Family Medicine & Nutrition Neurology news Radiology Specialties

Physical Exercise Slows Neurodegeneration and Cognitive Decline in Early Parkinson Disease: Insights from Longitudinal MRI Analysis

By MedXY 08/24/2025

Regular physical activity in early Parkinson disease patients is linked to slower brain atrophy in temporoparietal and limbic regions, mediating better preservation of memory and attention over four years.

Cardiology Diabetes & Endocrinology Family Medicine & Nutrition Neurology news Specialties

Clinical Therapeutic Value of Curcumin Supplementation in Cardiovascular Disease, Diabetes, Cognitive Function, Aging, and Neurodegenerative Disorders: A Synthesis of Recent Evidence

By MedXY 08/18/2025

Current evidence supports curcumin supplementation for reducing cardiovascular risk factors and preventing type 2 diabetes progression, with emerging potential in cognitive decline and aging-related degenerative diseases.

Family Medicine & Nutrition Medical News Neurology news Specialties

Can Preventing Herpes Reduce Dementia Risk? New Science Links Cold Sores, Shingles, and Alzheimer’s Disease

By MedXY 08/04/2025

Emerging research reveals a compelling connection between common herpes viruses and dementia risk, with vaccination and antiviral treatments showing promise for prevention.

Medical News Neurology news Specialties

Can Preventing Herpes Reduce Dementia Risk? New Science Links Cold Sores, Shingles, and Alzheimer’s Disease

By MedXY 08/04/2025

Emerging research reveals a compelling connection between common herpes viruses and dementia risk, with vaccination and antiviral treatments showing promise for prevention.

Neurology news Specialties

Understanding and Managing Alzheimer’s Disease: A Comprehensive Guide

By MedXY 08/03/2025

An in-depth overview of Alzheimer's disease, covering its causes, symptoms, diagnosis, treatment options, and caregiving strategies.