maternal vaccination

Maternal Vaccination and Infant Whole-Cell Pertussis Series Synergize for Superior Mucosal Immunity

By MedXY 01/24/2026

A phase 4 trial in The Gambia reveals that maternal Tdap-IPV vaccination provides early mucosal IgG to infants, while the DTwP primary series induces significantly stronger mucosal antibody and T-cell responses than DTaP, despite maternal antibody interference.

Infectious Diseases news Pediatrics

Nirsevimab Outperforms Maternal Vaccination in Reducing Severe RSV Outcomes: Insights from Comparative Real-World Evidence

By MedXY 12/23/2025

Recent real-world data from the US and France indicate that while both maternal RSV vaccination and nirsevimab are effective, nirsevimab may offer superior protection against hospitalization and intensive care admission for infants in their first respiratory syncytial virus season.

Pediatrics Public Health Specialties

Maternal Bivalent Prefusion F RSV Vaccine Significantly Reduces Infant Hospitalisation in UK: Real-World Evidence from a Multicentre Study

By MedXY 08/22/2025

A UK-wide multicentre study shows maternal bivalent RSV prefusion F vaccination reduces infant hospitalisation for RSV-associated ALRI by up to 72%, confirming real-world effectiveness matching clinical trials.