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PLCOm2012 Risk-Based Selection Outperforms NELSON Criteria for Lung Cancer Detection in Germany: Findings from the HANSE Cohort
Posted innews Oncology Respiratory

PLCOm2012 Risk-Based Selection Outperforms NELSON Criteria for Lung Cancer Detection in Germany: Findings from the HANSE Cohort

Posted by By MedXY 11/26/2025
In HANSE, PLCOm2012 (6‑year risk ≥1.58%) selected more lung cancers and yielded a lower number needed to screen than NELSON criteria, supporting risk-model selection for CT screening programs, with caveats on generalisability and mortality endpoints.
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Unraveling the Complexity of Lung Cancer Screening: Comparative Insights from Two Landmark Trials
Posted inClinical Updates news Oncology Specialties

Unraveling the Complexity of Lung Cancer Screening: Comparative Insights from Two Landmark Trials

Posted by By MedXY 09/14/2025
Lung cancer screening reduces mortality but varies by risk factors, sex, and cancer histology. Analysis of NELSON and NLST trials highlights histology-driven heterogeneity and suggests broader screening criteria may improve outcomes.
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