long-term outcomes

Low-Intensity Motivational Intervention Shows Durable Benefits 5 Years After Stroke: Insights from the TaCAS Long-Term Follow-Up

By MedXY 01/21/2026

The TaCAS long-term follow-up study reveals that a simple, conversation-based intervention can sustain improvements in physical health and independence for up to six years post-stroke, highlighting the lasting impact of patient-centered motivational strategies in chronic recovery.

Critical Care news Public Health

The Long Shadow of the ICU: Identifying High-Risk Functional Trajectories in Older Survivors

By MedXY 12/26/2025

A large-scale longitudinal study reveals that ICU survivors aged 60–79 face significantly higher 5-year excess mortality and functional decline compared to the general population, whereas outcomes for nonagenarians converge with their peers, highlighting a critical window for geriatric intervention and advance care planning.

news Radiology Urology

Five-Year Safety of Avoiding Biopsy After Negative MRI in Prostate Cancer Pathways

By MedXY 12/17/2025

Long-term data show RAPID MRI-directed pathway safely avoids unnecessary biopsies while maintaining low rates of clinically significant prostate cancer.

Critical Care news Rehabilitation Medicine

Early Neuromuscular Electrical Stimulation Plus Mobilization Improves 6‑Month Function and Quality of Life After Critical Illness

By MedXY 12/14/2025

In a randomized, blinded trial of 74 mechanically ventilated ICU patients, adding early NMES to an early mobilization program started within 48 hours improved functional status, independence, mobility, and quality of life up to 6 months after discharge versus mobilization alone.

Critical Care news Respiratory

Five-Year Survival and Quality of Life After ECMO: Good Long-Term Outcomes but Persistent Functional Burden

By MedXY 12/11/2025

A large prospective Dutch cohort reports 36% five-year survival after ECMO with generally satisfactory health-related quality of life (median EQ-5D 0.82) but ongoing problems with pain, mobility, activities, and work capacity.

Critical Care news

Simple Discharge Subtypes Predict 3‑Month Mortality and 1‑Year Disability After Sepsis: Validation in the CLOVERS Cohort

By MedXY 12/09/2025

A parsimonious discharge‑subtype algorithm applied to CLOVERS trial survivors stratified patients by 3‑month mortality and 12‑month functional outcomes, offering a pragmatic tool to target post‑hospital recovery resources.

Critical Care Nephrology news

Hospital Acute Kidney Injury Strongly Linked to Long-Term Death, Dialysis, and CKD: Meta-Analysis of Matched-Control Studies

By MedXY 12/09/2025

A meta-analysis of 14 matched-control studies (n=1,058,109) finds that survivors of in-hospital AKI face higher long-term mortality, greater subsequent dialysis need, and elevated risk of CKD versus matched controls.

Cardiology news

Seven-Year Outcomes of TAVR vs. Surgical Aortic Valve Replacement in Low-Risk Patients: Insights from PARTNER 3

By MedXY 10/31/2025

At 7 years, transcatheter and surgical aortic valve replacement show comparable outcomes including survival, stroke, and valve durability among low-risk patients with severe aortic stenosis, affirming TAVR's long-term efficacy.

Allergy & Immunology Hematology-Oncology news

Long-Term Safety and Efficacy of Gene Therapy for Adenosine Deaminase Deficiency

By MedXY 10/25/2025

This study demonstrates the long-term effectiveness and safety of autologous gene therapy for treating ADA deficiency, showing sustained immune function and minimal adverse effects over a median follow-up of 7.5 years.

Cardiology Neurology Orthopedics

Long-Term Outcomes of Extracranial Vertebral Artery Reconstruction in Managing Symptomatic Vertebral Artery In-Stent Restenosis or Occlusion

By MedXY 10/24/2025

This study evaluates the efficacy of vertebral artery reconstruction surgery versus medical therapy in reducing stroke recurrence and improving neurological outcomes over a ten-year period.

Dentistry Family Medicine & Nutrition news Otorhinolaryngology

Long-Term Outcomes of Oral Implant Rehabilitation in Patients with Disabilities Under General Anesthesia: A 14-Year Cohort Study

By MedXY 10/24/2025

This study evaluates the safety, effectiveness, and longevity of implant-supported prostheses in disabled patients treated under general anesthesia over 14 years.

Diabetes & Endocrinology General Surgery news

Long-Term Comparative Outcomes of Gastric Bypass and Sleeve Gastrectomy in Type 2 Diabetes: Evidence from a Swedish Matched Cohort Study

By MedXY 10/19/2025

A Swedish nationwide study reveals Roux-en-Y gastric bypass yields superior long-term benefits in type 2 diabetes remission and reduced mortality compared to sleeve gastrectomy, despite higher risks of nutritional deficiencies and psychiatric complications.

Psychiatry Public Health Specialties

Early Adolescent Mental Well-Being as a Predictor of Long-Term Health Outcomes

By MedXY 10/18/2025

This study highlights how poor mental well-being during adolescence predicts increased risks of mental illness, risky behaviors, and mortality in young adulthood, emphasizing the urgency for early identification and intervention.

Cardiology news

Long-Term Outcomes of Transcatheter Versus Surgical Aortic Valve Replacement: A Meta-Analysis of Time-to-Event Data

By MedXY 10/12/2025

This meta-analysis evaluates 5-year outcomes comparing TAVI and SAVR across risk profiles, revealing early advantages with TAVI that level off long-term, with no significant difference at 5 years.

news Orthopedics

Evaluating Long-Term Outcomes of Contemporary Arthroscopic Bankart Repair in Traumatic Anterior Shoulder Instability: Insights From a 10-Year Follow-Up Study

By MedXY 10/10/2025

This study examines long-term outcomes of a modern arthroscopic Bankart repair technique for traumatic anterior shoulder instability over a minimum 10-year follow-up, highlighting recurrence rates, risk factors, and functional results.

General Surgery news

Assessing the Long-Term Risk of Mesh Removal Due to Infection After Elective Ventral Hernia Repair

By MedXY 10/10/2025

A decade-long Medicare study shows low overall risk of mesh removal from infection after open ventral hernia repair, with a slightly higher risk in patients experiencing early wound complications.

Clinical Updates news Psychiatry Specialties

Balancing Risks and Benefits: Early Antipsychotic Dose Reduction Versus Maintenance After First-Episode Psychosis Remission

By MedXY 10/01/2025

A randomized clinical trial reveals early dose reduction of antipsychotics after first-episode psychosis remission increases short-term relapse risk and lowers quality of life, but may improve long-term functioning over four years.

Neurology news

Sustained Symptom Control over Five Years: Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson Disease

By MedXY 09/26/2025

Five-year follow-up from the INTREPID trial confirms that subthalamic nucleus deep brain stimulation significantly improves motor symptoms, reduces dyskinesia, lowers medication needs, and enhances daily living activities in moderate to advanced Parkinson disease patients, with an acceptable safety profile.

Clinical Updates Gastroenterology news Specialties

Early Control of Ulcerative Colitis and Its Impact on Long-Term Outcomes: Insights from the UNIFI Phase 3 Study

By MedXY 08/26/2025

Achieving disease clearance early after induction therapy with ustekinumab in ulcerative colitis patients predicts sustained clinical remission, symptom control, and improved quality of life over four years.

Clinical Updates Neurology news Specialties

Nine-Year Outcomes After Lacunar and Mild Cortical Ischemic Stroke: Long-Term Functional, Cognitive, and Vascular Impacts

By MedXY 08/26/2025

This longitudinal study reveals persistent cognitive, physical, and vascular challenges up to 9 years after minor lacunar or cortical ischemic stroke, emphasizing different risks and recovery patterns by stroke subtype.