influenza vaccine

High-Dose vs Standard-Dose Influenza Vaccine and Cardiovascular Outcomes in Older Adults: Insights from the DANFLU-2 Randomized Clinical Trial and Related Evidence

By MedXY 09/27/2025

This review synthesizes evidence on high-dose versus standard-dose influenza vaccines for cardiovascular outcomes in older adults, focusing on the large DANFLU-2 trial and complementary studies, highlighting modest cardiovascular benefits and implications for clinical practice.

Clinical Updates Wellness & Lifestyle

High-Dose vs Standard-Dose Influenza Vaccine in Older Adults: Insights from the DANFLU-2 Randomized Clinical Trial

By MedXY 09/06/2025

The DANFLU-2 trial demonstrates that high-dose influenza vaccine reduces cardiovascular and cardiorespiratory hospitalizations compared to standard-dose in adults ≥65 years, with similar benefits across subgroups including heart failure and atherosclerotic cardiovascular disease.

Clinical Updates Wellness & Lifestyle

Enhanced Protection in Heart Failure: High-Dose Influenza Vaccine Outperforms Standard Dose in the DANFLU-2 Trial

By MedXY 09/06/2025

The DANFLU-2 trial reveals that high-dose influenza vaccine significantly reduces hospitalization for influenza and cardiovascular events in older adults, including those with heart failure, compared to the standard-dose vaccine.

Clinical Updates Wellness & Lifestyle

PANDA II Trial Confirms Influenza Vaccination as Essential Intervention for Acute Heart Failure Patients

By MedXY 09/03/2025

The PANDA II study demonstrates that influenza vaccination significantly reduces mortality and rehospitalization in acute heart failure patients, supporting its inclusion as a standard component of heart failure management worldwide.

Clinical Updates Wellness & Lifestyle

High-Dose Influenza Vaccines Cut Hospitalizations: Landmark Trials Shape Cardiovascular Prevention

By MedXY 08/30/2025

Two massive randomized trials show high-dose flu vaccines reduce influenza-related and cardiorespiratory hospitalizations in older adults, reinforcing vaccination as a vital cardiovascular prevention strategy.

Medical News Wellness & Lifestyle

Comparing the Effectiveness of Influenza Vaccines: Subunit Vaccine vs. Split-Virion Vaccine

By MedXY 08/04/2025

A prospective study shows split-virion vaccines offer significantly higher protection against influenza than subunit vaccines in adults 50 and older, highlighting the importance of vaccine selection.