epilepsy – Medxy AI

Impaired Sleep Homeostasis and Respiratory Instability: Identifying Novel Biomarkers for Sudden Unexpected Death in Epilepsy

By MedXY 12/23/2025

This case-control study identifies altered slow-wave activity progression and increased respiratory variability during NREM sleep as significant biomarkers for SUDEP risk, providing a potential framework for objective clinical screening and risk stratification in epilepsy patients.

Neurology news

Do Behavioural, Self-Management, and Service Delivery Models Improve Outcomes in Adults with Epilepsy?

By MedXY 12/17/2025

A Cochrane review finds limited and low- to moderate-certainty evidence that behavioural, self-management, or service delivery interventions improve seizure control or quality of life in adults with epilepsy.

Neurology news Pediatrics

Limited Evidence for Behavioural and Service Delivery Interventions in Childhood Epilepsy: Urgent Need for Robust Trials

By MedXY 12/16/2025

Current evidence for behavioural and service delivery interventions in childhood epilepsy is scarce and of low quality, highlighting an urgent need for rigorous, long-term trials.

Neurology news Public Health

Geographic Clusters of Late-Life Epilepsy in US Medicare: Sleep and Mobility as Key Contextual Drivers

By MedXY 11/25/2025

A Medicare cohort study mapped incident epilepsy among older adults across the contiguous US and linked high-incidence areas to social and environmental determinants—most strongly insufficient sleep and lack of household vehicle access—suggesting targets for policy and prevention.

Neurology news

Decoding SUDEP: Key Risk Markers and the Role of Peri-Ictal Apnoea in Epilepsy Mortality

By MedXY 10/10/2025

A decade-long prospective study identifies living alone, convulsive seizure frequency, and peri-ictal apnoea as pivotal predictors for sudden unexpected death in epilepsy (SUDEP), highlighting the potential of cardiorespiratory monitoring in risk assessment.

Diabetes & Endocrinology Family Medicine & Nutrition Neurology news Pediatrics Specialties

Unraveling the Gut-Brain Axis: Microbiota and Metabolite Shifts Predict Seizure Reduction in Children on the Ketogenic Diet

By MedXY 08/08/2025

Serum metabolome and gut microbiota changes during ketogenic diet therapy correlate with seizure reduction in drug-resistant pediatric epilepsy, implicating plasmalogens and specific gut microbes in anti-seizure effects.