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ION224: A Promising Antisense Oligonucleotide Therapy for Metabolic Dysfunction-Associated Steatohepatitis (MASH)
Posted inClinical Updates Wellness & Lifestyle

ION224: A Promising Antisense Oligonucleotide Therapy for Metabolic Dysfunction-Associated Steatohepatitis (MASH)

Posted by By MedXY 08/27/2025
The phase 2 ION224-CS2 trial demonstrates that ION224, a DGAT2 antisense oligonucleotide, safely improves liver histology in MASH patients independent of weight loss, offering a potential new therapeutic approach.
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