CT perfusion – Medxy AI

Evaluating CT Perfusion and Angiography as Ancillary Tests for Brain Death Diagnosis: Insights from a Multicenter Canadian Study

By MedXY 10/27/2025

A large Canadian prospective study assessed brain CT perfusion and angiography for confirming death by neurologic criteria, highlighting high sensitivity but suboptimal specificity, emphasizing cautious use alongside clinical examination.

Neurology news Radiology Specialties

Noncontrast CT vs CT Perfusion Imaging in Acute Stroke: Comparative Insights from Recent Trials and Systematic Review

By MedXY 08/17/2025

Recent evidence from randomized trials and meta-analyses suggests that noncontrast CT (NCCT) offers comparable outcome prediction to CT perfusion (CTP) for selecting patients with acute ischemic stroke, including basilar artery occlusion, for endovascular therapy (EVT).

Clinical Updates Neurology news Specialties

JAMA: Extending Intravenous Alteplase to 24 Hours in Imaging‑Selected Ischemic Stroke (HOPE Trial)

By MedXY 08/10/2025

The HOPE randomized trial shows that CT‑perfusion–selected patients treated with intravenous alteplase at 4.5–24 hours (no planned thrombectomy) had higher 90‑day functional independence (40.3% vs 26.3%), with increased symptomatic intracranial hemorrhage but no higher mortality.