cognitive impairment

Elevated Cardiac Biomarkers Serve as Early Indicators of Structural Brain Damage and Cognitive Decline: Insights from the Hamburg City Health Study

By MedXY 12/25/2025

The Hamburg City Health Study reveals that elevated NT-proBNP and hs-cTnI are significantly linked to neurodegeneration and vascular brain injury. These cardiac biomarkers offer a non-invasive pathway for identifying patients at high risk for cognitive impairment and structural brain changes.

Neurology news Oncology

Chemoendocrine Therapy Linked to Greater Cognitive Decline in Breast Cancer Patients, Regardless of Menopausal Status

By MedXY 12/17/2025

A secondary analysis of the RxPONDER trial finds chemoendocrine therapy causes more lasting cognitive impairment than endocrine therapy alone in both pre- and postmenopausal women.

news Psychiatry

Large Phase 3 Trials Show No Cognitive Benefit with Iclepertin in Schizophrenia — What the CONNEX Programme Teaches Us About Treating CIAS

By MedXY 11/30/2025

Three multinational phase 3 trials found no clinically meaningful cognitive benefit of the GlyT1 inhibitor iclepertin versus placebo in schizophrenia, though the drug was well tolerated. Results highlight methodological and biological challenges in developing treatments for cognitive impairment associated with schizophrenia.

Neurology news Psychiatry

Cognitive Control Deficits in Specific Problematic Internet Uses: Insights From Clinically Validated Neurocognitive Assessments

By MedXY 10/30/2025

This study reveals distinct impairments in executive functions and inhibitory control across types of problematic internet use, highlighting the need for tailored interventions to address self-control deficits in internet addiction.

General Surgery Neurology Rehabilitation Medicine Specialties

Impact of Early Extracranial Surgery on One-Year Outcomes After Traumatic Brain Injury: Insights from the TRACK-TBI Study

By MedXY 10/21/2025

Early extracranial surgery following moderate-severe traumatic brain injury or positive CT findings is linked to worse cognitive, functional, and quality of life outcomes at one year, highlighting the need to refine surgical timing and post-injury interventions.

Clinical Updates Neurology news Specialties

Microbiome Virulence Signatures in the Oral-Gut-Brain Axis: New Insights into Parkinson’s Disease and Cognitive Decline

By MedXY 09/29/2025

This study reveals how virulence factors in oral and gut microbiomes and their translocation affect cognitive impairment in Parkinson’s disease, highlighting novel biomarker potential and the importance of the oral-gut-brain axis for early diagnosis and therapeutic strategies.

Neurology news Psychiatry Specialties

Impact of Screening and Care for Emotional and Cognitive Problems on Post-Ischemic Stroke Outcomes: Insights from a Dutch Multicenter Cluster-Randomized Trial

By MedXY 09/04/2025

A multicenter trial assessing emotional and cognitive screening post-ischemic stroke found no improvement in societal participation at 1 year, though modest early benefits in anxiety and quality of life were noted.

Medical News Neurology news Specialties

Legacy of Leaded Gasoline: New Evidence Links Childhood and Adult Exposure to Cognitive Impairment in Older Adults

By MedXY 07/30/2025

Recent studies confirm that both childhood and adult lead exposure, especially from gasoline and industrial sources, are associated with increased risk for cognitive decline and dementia in later life.