cardiometabolic health

Six Months of Intermittent Fasting: Potent Lipid Lowering but Limited Impact on Vascular and Glycemic Markers

By MedXY 01/20/2026

A randomized controlled trial investigates the 6-month effects of intermittent fasting on overweight adults, revealing significant improvements in lipid profiles and body composition despite neutral effects on blood pressure and glucose metabolism, alongside novel transcriptomic insights into GLP-1 signaling.

Cardiology Diabetes & Endocrinology news

Obesity as a Chronic Condition: Weight Regain Following Tirzepatide Withdrawal Reverses Vital Cardiometabolic Gains （SURMOUNT-4 trail）

By MedXY 01/01/2026

A post hoc analysis of the SURMOUNT-4 trial reveals that withdrawing tirzepatide leads to significant weight regain and a proportional reversal of improvements in blood pressure, glycemic control, and lipid profiles, reinforcing the necessity for long-term obesity management.

Cardiology Diabetes & Endocrinology news

Beyond the Heart: Why Metabolic Gains Are the True Drivers of GLP-1RA Cardioprotection

By MedXY 12/30/2025

A robust Mendelian randomization study demonstrates that the reduced risk of myocardial infarction associated with GLP-1 receptor agonists is primarily mediated by improvements in HbA1c, BMI, and lipid profiles, rather than direct cardiac effects.

Cardiology Family Medicine & Nutrition news Specialties

Divergent Impacts of Low- and High-Protein Fasting-Mimicking Diets on Cardiometabolic Health and Autophagy

By MedXY 08/30/2025

A 7-day randomized study shows that both low- and high-protein fasting-mimicking diets improve cardiometabolic health and autophagy, with high-protein variants uniquely enhancing visceral fat reduction, lipid profiles, heart rate variability, and gut microbiome diversity.

Cardiology Public Health Respiratory Specialties

Ventilation Hoods During Cooking Significantly Reduce PM2.5 Exposure and Improve Cardiometabolic and Pulmonary Health: Evidence from a Cluster-Randomized Trial in Rural China

By MedXY 08/30/2025

A community-based intervention using ventilation hoods during cooking reduced 24-hour PM2.5 exposure by nearly 30% and improved cardiometabolic and pulmonary health markers in rural Chinese villages reliant on wood fuel.

Cardiology Family Medicine & Nutrition Medical News Neurology news Psychiatry Specialties

Irregular Sleep Patterns: Unveiling Hidden Health Risks Across Metabolic, Cardiovascular, and Mental Domains

By MedXY 08/08/2025

Recent studies link irregular sleep to higher risks of type 2 diabetes, cardiometabolic diseases, all-cause mortality, and depression. Consistent sleep timing may offer crucial protection against these adverse outcomes.