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Personalised T-Cell Activation Shows Promise in Overcoming Minimal Residual Disease in Chronic Lymphocytic Leukaemia
Posted inHematology-Oncology news

Personalised T-Cell Activation Shows Promise in Overcoming Minimal Residual Disease in Chronic Lymphocytic Leukaemia

Posted by MedXY By MedXY 02/18/2026
A Phase 1 study demonstrates that iTAC-XS15-CLL01, a personalised multipeptide T-cell activator, induces robust immune responses in 95% of CLL patients on BTK inhibitors, offering a potential path to sustainable cancer control and eradication of minimal residual disease.
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Fenebrutinib Achieves 69% Reduction in New Brain Lesions for Relapsing Multiple Sclerosis: Insights from the FENopta Phase 2 Trial
Posted inNeurology news Rheumatology

Fenebrutinib Achieves 69% Reduction in New Brain Lesions for Relapsing Multiple Sclerosis: Insights from the FENopta Phase 2 Trial

Posted by MedXY By MedXY 12/23/2025
The Phase 2 FENopta trial demonstrates that fenebrutinib, a highly selective, reversible BTK inhibitor, significantly reduces MRI disease activity by 69% in relapsing multiple sclerosis while maintaining a favorable safety profile over 48 weeks.
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  • Predicting Ocular Relapse in Sarcoid Uveitis: Macular Edema and Baseline Inflammation as Critical Prognostic Markers
  • Liquid Biopsy Predicts Recurrence in HPV-Independent Head and Neck Cancer Months Before Imaging
  • In-Lab vs. At-Home Sleep Studies: Determining Minimum Recording Time and the Role of Positional Sleep Apnea
  • Navigating the Adhesion Maze: How Previous Abdominal Surgeries Impact Bariatric Outcomes
  • Wearable TEAS Outperforms Metoclopramide in Managing Moderate to Severe Postoperative Nausea and Vomiting
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