blood-based biomarkers

Advances in Alzheimer’s Diagnosis: A Comprehensive Review of CSF and Blood Biomarkers

By MedXY 10/20/2025

This article reviews a systematic meta-analysis of 15 cerebrospinal fluid and blood biomarkers for Alzheimer's disease, highlighting robust diagnostic performance of core markers T-tau, P-tau, and Aβ42 in clinical practice and research.

Nephrology Neurology news

Assessing the Role of Kidney Function in Alzheimer’s Disease Blood Biomarker Interpretation and Amyloid-β Positivity Prediction

By MedXY 10/20/2025

Kidney function influences certain Alzheimer's disease blood biomarker levels but, within normal to mild impairment ranges, does not improve prediction of amyloid-β positivity, supporting the clinical utility of blood biomarkers in AD diagnosis regardless of renal status.

Internal Medicine Neurology news

Unraveling Blood-Based Biomarkers in Neurodegenerative Diseases: Insights from the Young Finns Study on Intergenerational and Metabolic Influences

By MedXY 10/20/2025

This cohort study from the Young Finns Study elucidates factors influencing blood-based biomarkers for neurodegenerative diseases, highlighting age, APOE ε4 genotype, kidney function, metabolic parameters, and notable intergenerational associations.