biomarker – Medxy AI

A viral clonality evenness score accurately identifies HTLV‑1 carriers at high risk of adult T‑cell leukaemia

By MedXY 11/27/2025

A clonality evenness score (VCE) derived from HTLV‑1 integration sequencing discriminates asymptomatic carriers who later develop adult T‑cell leukaemia from those who do not, outperforming proviral load alone in individual-level prediction in a Japanese longitudinal cohort.

news

Revolutionizing Endometriosis Diagnosis: Validation of a Saliva-Based microRNA Signature

By MedXY 10/30/2025

A prospective multicenter study validates the high accuracy of a saliva microRNA signature for noninvasive endometriosis diagnosis, demonstrating superior performance to imaging modalities and promising clinical utility.

Gastroenterology news Oncology

Proteogenomic Insights into Personalized Adjuvant Chemotherapy for Extrahepatic Cholangiocarcinoma

By MedXY 10/28/2025

Comprehensive proteogenomic profiling in resected extrahepatic cholangiocarcinoma reveals predictive biomarkers for tailoring adjuvant chemotherapy, offering a precision medicine approach to improve patient outcomes.

Critical Care Gastroenterology news

RIPK3 as a Prognostic Biomarker in Acute Decompensation of Cirrhosis: Advancing Risk Stratification and Therapeutic Targeting

By MedXY 10/28/2025

RIPK3-associated necroptosis critically drives organ failure and mortality in acute decompensation and ACLF, with its plasma levels robustly predicting outcomes and improving prognostic models to guide personalized therapies.

Medical News Neurology Pathology & Lab Medicine

Blood Test Breakthrough: Detecting ALS Over a Decade Before Symptoms Emerge

By MedXY 09/04/2025

New research identifies a protein signature in blood that detects ALS years before symptoms, challenging previous perceptions and offering hope for early diagnosis and intervention.