Reevaluating Beta-Blocker Therapy Post-Myocardial Infarction with Preserved Ejection Fraction: Insights from Recent Trials and Meta-Analyses

Reevaluating Beta-Blocker Therapy Post-Myocardial Infarction with Preserved Ejection Fraction: Insights from Recent Trials and Meta-Analyses

Recent evidence challenges the routine use of long-term beta-blockers after myocardial infarction in patients with preserved ejection fraction, highlighting comparable outcomes with or without therapy and raising safety and efficacy considerations in contemporary practice.
Safety of Beta Blocker Withdrawal After Myocardial Infarction Without Reduced Ejection Fraction: Insights from the REBOOT Trial Post Hoc Analysis

Safety of Beta Blocker Withdrawal After Myocardial Infarction Without Reduced Ejection Fraction: Insights from the REBOOT Trial Post Hoc Analysis

Post hoc analysis of the REBOOT trial shows that withholding or withdrawing beta blockers after myocardial infarction in patients with preserved LVEF (>40%) does not increase short-term or recurrent ischaemic events, challenging current universal beta blocker recommendations.