asthma – Medxy AI

Unveiling Diverse Inflammatory Pathways in Residual Pediatric Asthma Exacerbations Under Mepolizumab Therapy

By MedXY 10/27/2025

This study reveals multiple distinct molecular mechanisms, including epithelial and macrophage pathways, that contribute to residual asthma exacerbations in children treated with mepolizumab, highlighting the complexity of airway inflammation.

news Pediatrics Respiratory

Budesonide-Formoterol Reliever Therapy Demonstrates Superiority over Salbutamol in Children with Mild Asthma: Insights from the CARE Trial

By MedXY 10/10/2025

The CARE trial shows that budesonide-formoterol reliever monotherapy significantly reduces asthma attack rates compared to salbutamol in children aged 5-15 years with mild asthma, with comparable safety over 52 weeks.

Allergy & Immunology news Respiratory

Persistent Use of Green Cleaning Products Linked to Increased Asthma Risk: Implications for Clinical Practice

By MedXY 10/09/2025

Longitudinal data from the French NutriNet-Santé cohort reveal that persistent and increased use of green cleaning products is associated with a modest but significant rise in asthma symptoms, underscoring the need for cautious use and patient counseling.

Allergy & Immunology Cardiology Respiratory Specialties

Asthma and the Risk of Degenerative Valvular Heart Disease: Insights from a Large Prospective Cohort Study

By MedXY 08/21/2025

This study demonstrates that asthma modestly increases the risk of degenerative valvular heart diseases, highlighting the need for cardiovascular vigilance in asthmatic individuals.

Allergy & Immunology Clinical Updates Neurology news Psychiatry Respiratory Specialties

Empowering Parents: Acceptance and Commitment Therapy for Children With Asthma and ADHD

By MedXY 08/04/2025

A randomized clinical trial demonstrates that an Acceptance and Commitment Therapy-based parenting program reduces health care use, improves asthma control, and alleviates ADHD symptoms in children with both conditions.

news Respiratory Specialties

As-Needed Albuterol–Budesonide Therapy in Mild Asthma: Clinical Impact and Comparative Evidence

By MedXY 08/01/2025

As-needed albuterol–budesonide significantly reduces severe exacerbations in mild asthma compared to albuterol alone, with comparable safety. Two pivotal trials confirm efficacy across lung function and exacerbation outcomes.

Allergy & Immunology Clinical Updates news Specialties

Cockroach Immunotherapy Modulates Key T-Cell Responses Regardless of Allergen Extract Abundance

By MedXY 07/30/2025

A randomized trial finds that subcutaneous cockroach immunotherapy effectively downregulates dominant T-cell responses in pediatric asthma, independent of allergen abundance in the therapeutic extract.

Allergy & Immunology Clinical Updates news Respiratory Specialties

Digital Self-Management Tools Enhance Asthma Control

By MedXY 07/30/2025

A randomized trial shows that a smartphone-based asthma self-management program improves symptom control in adults, though its effectiveness is attenuated in African American participants.