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Comparative Effectiveness of Long-Acting Injectable Versus Oral Antipsychotics in Older Adults with Schizophrenia: Insights from Hong Kong’s Population-Based Study
Posted inInternal Medicine Psychiatry Specialties

Comparative Effectiveness of Long-Acting Injectable Versus Oral Antipsychotics in Older Adults with Schizophrenia: Insights from Hong Kong’s Population-Based Study

Posted by MedXY By MedXY 10/18/2025
This study compares long-acting injectable to oral antipsychotics in older schizophrenia patients, highlighting benefits in relapse prevention and mortality reduction, with specific considerations for adverse effects.
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Enhancing Patient Experience in DLBCL: Insights from PROs and Clinician-Reported AEs in the Phase 3 POLARIX Trial
Posted inHematology-Oncology news

Enhancing Patient Experience in DLBCL: Insights from PROs and Clinician-Reported AEs in the Phase 3 POLARIX Trial

Posted by MedXY By MedXY 10/14/2025
The POLARIX trial demonstrates superior progression-free survival with Pola-R-CHP in untreated DLBCL, highlighting the utility of patient-reported outcomes alongside clinician-reported adverse events to capture symptom burden and quality of life comprehensively.
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Balancing Benefits and Harms of Intensive Blood Pressure Control Across Cardiovascular Risk Levels
Posted inCardiology Clinical Updates news Specialties

Balancing Benefits and Harms of Intensive Blood Pressure Control Across Cardiovascular Risk Levels

Posted by MedXY By MedXY 08/12/2025
Intensive blood pressure control reduces cardiovascular events across all risk levels, with greater absolute benefits in higher-risk patients despite increased adverse events, supporting tailored treatment based on cardiovascular risk.
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Testosterone Therapy in Middle-Aged and Older Men with Hypogonadism: Balancing Clinical Benefits and Risks
Posted inClinical Updates news Specialties Urology

Testosterone Therapy in Middle-Aged and Older Men with Hypogonadism: Balancing Clinical Benefits and Risks

Posted by MedXY By MedXY 08/07/2025
Testosterone therapy offers modest benefits for sexual function, anemia, and bone health in older men with hypogonadism, but increases risks of venous thromboembolism, fractures, and arrhythmias. Careful patient selection and individualized risk-benefit assessment are essential.
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Mini Copper IUDs: Efficacy, Safety, and Continuation Compared to Standard Devices
Posted inClinical Updates news OB/GYN & Women's Health Specialties

Mini Copper IUDs: Efficacy, Safety, and Continuation Compared to Standard Devices

Posted by MedXY By MedXY 08/05/2025
A large randomized trial demonstrates that the NTCu380 Mini copper IUD offers comparable contraceptive efficacy to the standard TCu380A, with fewer side effects leading to discontinuation, especially in nulliparous women.
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  • Early Inpatient Initiation of 1-Month TB Preventive Therapy Proves Non-Inferior for Patients with Advanced HIV and Cryptococcal Meningitis
  • Systematic Complication Management Boosts Long-Term Survival in Pancreatic Cancer: Insights from the PORSCH Trial
  • Surgical Fixation Offers No Clinical Benefit and Zero Cost-Effectiveness for Pediatric Medial Epicondyle Fractures: Results from the SCIENCE Trial
  • Selective TRPC6 Inhibition Emerges as a Novel Therapeutic Paradigm for Focal Segmental Glomerulosclerosis
  • Doravirine and Islatravir Combination Proves Non-Inferior to B/F/TAF: A New Era for Two-Drug HIV Maintenance
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