Waist Size Proves Key to Assessing Liver Health
Waist circumference is a superior predictor of metabolic liver diseases, outperforming BMI and other body metrics in assessing MASLD, MASH, and liver stiffness risks.
Posted inCardiology Clinical Updates news Pediatrics Specialties
Silent Damage: Blood Pressure and Subclinical Cardiovascular Injury in Adolescents—Insights from the SHIP AHOY Study
The SHIP AHOY Study demonstrates that even modest elevations in blood pressure during adolescence are linked to a greater burden of subclinical target organ injury, underscoring the importance of early detection and intervention.
Posted inClinical Updates news Oncology Specialties
Decoding Oncology Trial Endpoints: OS, DFS, PFS, ORR, CR, PR, SD, PD, and DCR Explained
This article demystifies key clinical trial efficacy endpoints in oncology, including OS, DFS, PFS, ORR, CR, PR, SD, PD, and DCR, providing clinicians with a practical guide to their definitions, roles, and interpretation.
Posted inClinical Updates news Oncology Specialties
Beyond Negative: Quantitative Fecal Hemoglobin Levels Refine Colorectal Cancer Risk Stratification in FIT-based Screening
New meta-analysis reveals a strong dose-response relationship between fecal hemoglobin concentration and colorectal neoplasia risk, even among FIT-negative individuals, supporting personalized screening intervals.
Posted inClinical Updates news Oncology Specialties
Overcoming PD-1 Inhibitor Resistance: Six Emerging Strategies from the 2025 ASCO Annual Meeting
PD-1 inhibitor resistance is a major hurdle in cancer immunotherapy. Six leading combination strategies—including chemotherapy, anti-angiogenic agents, radiotherapy, novel checkpoint inhibitors, microbiome modulation, and ADCs—offer new hope for overcoming resistance and improving patient outcomes.
Posted inCardiology Clinical Updates news Specialties
Unveiling Altered Blood Pressure Reflexes in Women with Endometriosis: Implications for Cardiovascular Health
Women with endometriosis exhibit blunted blood pressure responses to physiological stress, challenging prior assumptions about their cardiovascular risk profile. Aspirin, a COX inhibitor, does not modify these attenuated responses.
Posted inClinical Updates news Respiratory Specialties
AI-Enhanced Spirometry Interpretation in Primary Care: Evidence from a Randomized Controlled Trial
AI decision support significantly improves primary care clinicians’ accuracy in spirometry diagnosis, especially for COPD, addressing a key gap in respiratory disease management.
Posted inCardiology Clinical Updates news Specialties
Hypertension and the Gut Microbiome: New Frontiers in Blood Pressure Management
Emerging evidence links gut microbiome alterations to hypertension, offering novel therapeutic opportunities. Interventions like dietary fiber, probiotics, and even fecal microbiota transplantation show promise for patients with treatment-resistant hypertension.
Posted inCardiology Clinical Updates news Specialties
Rethinking Hypertension: Beyond the Kidney-Centered Paradigm
Emerging evidence points to a multifactorial etiology of primary hypertension, challenging the traditional kidney-centric perspective and highlighting the need for integrated approaches in prevention and management.
Posted inClinical Updates news Nursing & care Specialties
Benchmarking Autonomous AI Doctors: Real-World Validation Against Board-Certified Clinicians in Virtual Acute Care
A landmark study quantitatively benchmarks a multi-agent LLM-based AI system against board-certified clinicians in real-world virtual acute care, revealing near-equivalent diagnostic and therapeutic performance with superior documentation safety and consistency.
Posted inFamily Medicine & Nutrition news Specialties
40 Essential Health Tips You Should Know
Discover 40 essential health tips to prevent diseases, safely use medication, maintain a nutritious diet, and adopt healthy lifestyle habits.
Posted inInfectious Diseases news Specialties
Common Infectious Diseases in Summer and Their Prevention
An overview of common infectious diseases during summer, their symptoms, transmission, and preventive measures to protect public health.
Summer Heat and Your Body’s Messages: Understanding Signals to Prevent Heatstroke
Learn how your body responds to high temperatures and how to recognize signs of heat stress to prevent heatstroke during summer heatwaves.
Posted innews Orthopedics Specialties
How People with Gout Can Eat for Better Health
Guidance on dietary management for gout patients focusing on purine intake, hydration, and balanced nutrition to prevent flare-ups and promote health.
Posted inCardiology news Specialties
How Should People with Hypertension Eat for Better Health? — Dietary Guidelines for Hypertensive Patients
This article provides practical dietary and lifestyle recommendations to help individuals with hypertension manage their condition and reduce cardiovascular risks.
Posted inMedical News news Oncology Specialties
Alcohol Intake and Pancreatic Cancer: New Global Data Clarifies the Risk
A large pooled analysis across continents confirms a linear, dose-dependent association between alcohol consumption and pancreatic cancer risk—independent of smoking status and with significant public health implications.
Posted inClinical Updates news Oncology Specialties
Tibremciclib Sets New Benchmark in Advanced HR+/HER2- Breast Cancer: Near Tripling of Progression-Free Survival
The TIFFANY phase 3 trial demonstrates tibremciclib plus fulvestrant extends progression-free survival nearly threefold in advanced HR+/HER2- breast cancer following endocrine therapy, with a 63% risk reduction for progression or death and manageable safety.
Posted inClinical Updates news Oncology Specialties
A New Era in Refractory Neuroblastoma: First-in-Class Triple Therapy Achieves 75% Disease Control in Children
A phase I trial published in JCO demonstrates that a novel combination of MIBG, dinutuximab, and vorinostat achieves up to 75% disease control in relapsed/refractory neuroblastoma, offering new hope for high-risk pediatric patients.
Posted inClinical Updates news Oncology Specialties
Eradication of Helicobacter pylori Significantly Reduces Gastric Cancer Incidence and Mortality, with Clearer Benefits in High-Risk Populations
A comprehensive meta-analysis confirms that Helicobacter pylori eradication reduces gastric cancer risk and related deaths, especially benefiting high-risk groups, supporting widespread screening and treatment.
Intermediate-Dose Cytarabine Matches High-Dose Efficacy with Fewer Side Effects in Postinduction AML Therapy
A major RCT shows intermediate-dose cytarabine is noninferior to high-dose as postinduction therapy in AML, with similar survival and lower toxicity.