Morning or Evening? The Science Behind The Best Time to Exercise for Weight Loss and Muscle Growth
Discover how exercising at 7 AM or 7 PM can boost weight loss and muscle growth, tailored to your body's rhythms and lifestyle.
Ankle Pumps: The Simple Yet Powerful Exercise for Circulation, Strength, and Recovery
Ankle pumps are a versatile exercise beneficial for blood circulation, muscle strengthening, injury prevention, and rehabilitation. This comprehensive guide explains their science, usage, and practical tips for all ages and health conditions.
Posted inOncology Radiology Specialties
Mupirocin Nasal Ointment Significantly Reduces Severe Acute Radiation Oral Mucositis in Nasopharyngeal Cancer Patients: Insights from a Phase 3 Trial
A phase 3 trial demonstrates that mupirocin nasal ointment used for bacterial decolonization effectively lowers severe acute radiation oral mucositis rates, improves quality of life, and reduces Staphylococcus aureus colonization in nasopharyngeal cancer patients undergoing radiotherapy.
Posted inOncology Specialties
Long-Term Durability of Active Surveillance in Small, Low-Risk Papillary Thyroid Cancer: Age-Related Outcomes and Clinical Implications
Active surveillance is a durable management strategy for small, low-risk papillary thyroid cancer, especially among older adults who show significantly lower crossover rates to surgery.
Posted inNephrology Oncology Specialties
Predicting Chronic Kidney Disease After Cisplatin Treatment: Insights from Population-Level Data
Cisplatin chemotherapy is associated with predictable kidney function decline, with pre-treatment eGFR effectively forecasting chronic kidney disease risk post-treatment. Simple models outperform complex approaches, offering practical clinical decision tools.
Posted inPediatrics Public Health Specialties
Maternal Bivalent Prefusion F RSV Vaccine Significantly Reduces Infant Hospitalisation in UK: Real-World Evidence from a Multicentre Study
A UK-wide multicentre study shows maternal bivalent RSV prefusion F vaccination reduces infant hospitalisation for RSV-associated ALRI by up to 72%, confirming real-world effectiveness matching clinical trials.
Posted inOB/GYN & Women's Health Specialties
Unraveling Menopause: Symptom Prevalence and Severity Across the Transition—Insights from the Australian Women’s Midlife Years (AMY) Study
The AMY Study highlights vasomotor symptoms, particularly hot flushes, as key indicators of perimenopause onset, challenging traditional cycle-based definitions and underscoring the need for tailored symptom management across diverse reproductive stages.
Posted inPsychiatry Specialties
Clozapine and Infection Risk in Schizophrenia: Insights from a Hong Kong Population Study
This study reveals an increased risk of infections among schizophrenia patients treated with clozapine compared to olanzapine, highlighting the need for vigilant infection monitoring and preventive care.
Posted inNeurology Specialties
Apitegromab (SAPPHIRE): phase 3 trial shows modest motor gains in non‑ambulatory type 2/3 spinal muscular atrophy on SMN therapies
The SAPPHIRE phase 3 trial found that adding apitegromab to nusinersen or risdiplam produced a small but statistically significant improvement in motor function in children aged 2–12, with a safety profile similar to placebo.
Posted inNeurology Specialties
Unlocking Dementia Prevention in Brazil: Impact of 14 Modifiable Risk Factors on Reduction Potential
Nearly 60% of dementia cases in Brazil could be prevented by addressing 14 modifiable risk factors, highlighting a crucial public health opportunity in a middle-income country setting.
Posted inGeneral Surgery Specialties
Reevaluating the Necessity of Nasogastric Tubes After Oesophagectomy: Insights from a Nordic Multicentre Trial
A comprehensive Nordic trial reveals that postoperative nasogastric tube removal may increase anastomotic leak risk after oesophagectomy, suggesting continued use of NG tubes for patient safety.
Posted inDiabetes & Endocrinology Specialties
What’s New in Diabetes Care 2024: Key Recommendations from the ADA Standards of Care
A practical, clinician-friendly summary of the American Diabetes Association’s 2024 Standards of Care, highlighting new recommendations on GLP-1/GIP therapy, SGLT2 inhibitors, continuous glucose monitoring, and individualized care.
Posted inGeneral Surgery Oncology Specialties
Clinical Presentation, Management, and Outcomes of 11,132 Liposarcoma Patients: Insights from the NETSARC+ Registry
The NETSARC+ registry study comprehensively characterizes liposarcoma histotypes, revealing diverse clinical presentations, management strategies, and prognoses, with dedifferentiated liposarcoma having the poorest survival and age-sex specific prognostic differences.
Posted inClinical Updates Specialties
Safety and Efficacy of Rotigotine in Frontotemporal Dementia: Insights from a Phase 2 Double-Blind Multicenter Trial
This phase 2 trial found no significant cognitive or behavioral benefits of rotigotine in bvFTD patients over 24 weeks, highlighting the challenges in dopaminergic therapy for frontotemporal dementia.
Posted inOncology Public Health Specialties
Socioeconomic Disparities in Intrahepatic Cholangiocarcinoma in Sweden: Incidence, Treatment, and Survival in a Universal Healthcare Context
A nationwide Swedish study reveals significant socioeconomic disparities in intrahepatic cholangiocarcinoma incidence, treatment access, and survival despite universal healthcare coverage, underscoring persistent health inequities linked to income.
Posted inCardiology Specialties
Sex-Specific Genetic Insights into Dilated Cardiomyopathy: The Key Role of Desmoplakin Variants
Desmoplakin gene variants confer a higher risk and penetrance of dilated cardiomyopathy in females, contrasting with male-predominant risks from other genes like TTN. This discovery underscores sex-specific mechanisms in DCM susceptibility and prognosis.
Posted inFamily Medicine & Nutrition Specialties
The Hidden Power of Ankle Pump Exercises: A Simple Way to Prevent Blood Clots
Discover how ankle pump exercises, an easy and efficient way to boost circulation, can help prevent blood clots, especially for those with sedentary lifestyles.
PANLAR 2025 Recommendations for Polyarticular Juvenile Idiopathic Arthritis in Latin America — Practical, Evidence-Based Guidance for Resource-Variable Settings
PANLAR’s 2025 evidence-based recommendations for non-systemic polyarticular JIA emphasize early treat-to-target care using methotrexate, targeted escalation to biologics when needed, region-sensitive alternatives (leflunomide, triple nbDMARD therapy), and limited steroid bridging to improve outcomes in Latin America.
Posted inDiabetes & Endocrinology Specialties
ADA Standards of Care 2024: A Clinician-Friendly Guide to the New Cardiorenal‑Metabolic Era in Diabetes Care
The ADA's 2024 Standards refocus diabetes care around cardiorenal protection, expanded use of GLP‑1 and SGLT2 therapies, wider adoption of glucose‑sensing technology, and integrated obesity management.
Posted inCardiology Specialties
Clinical Outcomes of Conduction System Pacing vs Right Ventricular Septal Pacing in Atrioventricular Block: Insights from the CSPACE Randomized Controlled Trial
This review synthesizes evidence from the CSPACE RCT demonstrating superior clinical outcomes of conduction system pacing over right ventricular septal pacing in AV block patients, emphasizing reduced pacing-induced cardiomyopathy and CRT upgrade rates.